속발성으로 발생한 인체유두종바이러스 연관 두경부 이차암 1예
A Case of Metachronous Human Papilloma Virus-Associated Squamous Cell Carcinomas in Head and Neck
Synchronous or metachronous head and neck cancer is known to occur in up to 20% of patients, negatively affecting long-term prognosis. We experienced a case of metachronous head and neck cancers in a Human papillomavirus (HPV)-positive patient without a history of smoking, initially presenting with as a cancer of unknown primary (CUP), and then with a contralateral tonsil cancer with metastatic lymphadenopathy five years later. This report highlights the clinical usefulness of HPV typing to determine the optimal extent of surgery and the follow-up strategy in CUP. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(3):233-7
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