본문 바로가기
HOME> 논문 > 논문 검색상세

학위논문 상세정보

락탐화합물의 고리확장연구 : 입체선택성과 Mechanism에 관한 연구 원문보기

  • 저자

    최경민

  • 학위수여기관

    昌原大學校

  • 학위구분

    국내석사

  • 학과

    化學科化學專攻

  • 지도교수

  • 발행년도

    2002

  • 총페이지

    vi, 58 p.

  • 키워드

  • 언어

    kor

  • 원문 URL

    http://www.riss.kr/link?id=T8936000&outLink=K  

  • 초록

    The ring expansion chemistry is one of the most important methods to prepare five- and six-membered hetero cyclic compounds. we have studied about γ-lactam ring expansion with steroselectivity from β-lactam derivative. To do this chemistry, proton of N-benzyl group in β-lactam derivatives is eliminated by LDA and make carbanion. This anion make unstable 4-membered lactam intermediate, and then the ring is opened by homo cleavage or hetero cleavage for releasing ring strain, followed by recyclization to insert one carbon to make γ-lactam ring with stereoselectivity in β-, γ- positions.


 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역