囊腫 手術 前後에 있어서 血中 Alkaline Phosphatase의 變化에 對한 硏究
Change of Serum Alkaline Phosphatase in Cyst Enucleation of the Jaw
낭종 수술 Alkaline Phosphatase;
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This study was to analyze the variation of levels of alkaline phosphatase before and after enucleation of jaw cysts combined with bone grafting, and to evaluate biochemically the effectiveness of the early detection of bony healing and infection as a prognostic marker. Eighteen patients (13 males, 5 females) with cystic lesions of the jaw were divided into two groups. The bone graft group underwent enucleation and bone graft. The control group underwent only enucleation. Levels of ALP on both groups were measured preoperatively and 4 weeks postoperatively. The more discriminating results were obtained in the bone graft group. The results were as follows : 1. Levels of ALP after enucleation of jaw cysts were decreased in all patients regardless bone graft. 2. The bone graft group showed more marked decrease in variation of levels of ALP than the control group. This should be considered as a result of increased osteoblastic activity and new bone formation. 3. Such variation could be used as a prognostic marker for bone healing after cyst enucleation. In the cost/benefit ratio, measurement of ALP activity could be useful as a convenient procedure in routine clinical practice.