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급성 심장사의 원인질환에 따른 면역조직화학염색의 유용성 원문보기
Usefulness of immunohistochemistry in various types of sudden cardiac death

  • 저자

    김진석

  • 학위수여기관

    경북대학교 대학원

  • 학위구분

    국내박사

  • 학과

    의학과 법의학전공

  • 지도교수

  • 발행년도

    2004

  • 총페이지

    27, iip.

  • 키워드

    면역조직화학염색 원인질환 급성 심장사;

  • 언어

    kor

  • 원문 URL

    http://www.riss.kr/link?id=T10045598&outLink=K  

  • 초록

    Postmortem diagnosis of early myocardial infarction is still a puzzling problem in forensic pathology practice, especially in sudden cardiac death. This study was undertaken to evaluate the distribution patterns of several immunohistochemical markers in various types of sudden cardiac death; 27 cases of obstructive coronary atherosclerosis(SCD-CAD) including 13 cases of critical coronary atherosclerosis, 6 cases of atherosclerotic heart disease and 8 cases of acute myocardial infarction, 26 cases of sudden cardiac death with obvious other causes(SCD-miscellaneous) including hypertensive heart disease, arrhythmogenic right ventricular cardiomyopathy, etc. and 14 cases of sudden cardiac death without any myocardial changes and/or minimal coronary atherosclerosis(SCD-unknown). 10 cases of unnatural death were included in control group. Imnunohistochemical reactivity and the severity of reactivity loss were evaluated. The immunoreactivity against myoglobin and troponin C were excellent, and their reactivity loss were statistically significant in SCD-CAD compared to control group, SCD-unknown and SCD-miscellaneous(p


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