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Diethylnitrosamine 투여 후 5-fluorouracil 처리에 의한 랫트간의 기능학적 및 형태학적 변화 원문보기
Functional and morphological changes of the livers by 5-fluorouracil treatment on diethylnitrosamine-treated rat

  • 저자

    권지인

  • 학위수여기관

    慶尙大學校 大學院

  • 학위구분

    국내석사

  • 학과

    수의학과

  • 지도교수

  • 발행년도

    2004

  • 총페이지

    ii, 25p.

  • 키워드

    DIETHYLNITROSAMINE 5-FLUOROURACIL처리 랫트간 수의학;

  • 언어

    kor

  • 원문 URL

    http://www.riss.kr/link?id=T10059986&outLink=K  

  • 초록

    5-Fluorouracil (5-FU) is one of the most widely used anticancer agent for digestive cancers including hepatocellular carcinoma, and is known to affect the cell cycle and induce apoptosis of cancer cells. In the present study, female Sprague-Dawley rats were given drinking water containing 0.01% diethylnitrosamine (DEN) for 6 weeks. We examined functional and morphological changes of livers by 5-FU treatments on DEN-treated rat. The DEN-treated rats compared to 5-FU-treated rats after DEN treatment for 6 weeks. The serum total protein and triglyceride were significantly (P


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