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쯔쯔가무시병 환자의 중증도와 관련된 상부 위장관 내시경 소견 및 예측 인자들에 관한 연구 원문보기
Upper Gastrointestinal Endoscopic Features and Predictable Factors for Clinical Severity in the Patients with Tsutsugamushi Disease

  • 저자

    박정호

  • 학위수여기관

    慶尙大學校 大學院

  • 학위구분

    국내석사

  • 학과

    의학과

  • 지도교수

  • 발행년도

    2004

  • 총페이지

    29p.

  • 키워드

    쯔쯔가무시병 위장관 내시경 의학;

  • 언어

    kor

  • 원문 URL

    http://www.riss.kr/link?id=T10060314&outLink=K  

  • 초록

    Background/Aims: Scrub typhus is a febrile zoonosis resulting from infection with Orientia tsutsugamushi. Attentions for tsutsugamushi disease are growing about its ecologic, epidemiologic and clinical characteristics according to increasing patients and these studies were helpful to understand the pathophysiology and many clinical features of Tsutsugamushi disease. Although scrub typhus has been treated successfully with the introduction of effective antibiotics, life-threatening serious complications including gastrointestinal bleeding were still remained. The author here intended to describe different endoscopic characteristics of the gastrointestinal manifestation of Tsutsugamushi disease, and then to evaluate the clinical significance of upper gastrointestinal endoscopic feature and clinical severity index (CSI) as the predictable factors for clinical severity of Tsutsugamushi disease. Methods: One hundred and forty two patients who were diagnosed as Tsutsugamushi disease at Masan-Samsung Hospital from January 2001 to December 2002 were enrolled. Patients were recommended to be taken upper gastrointestinal endoscopy irrespective of abdominal symptoms. Three patients were excluded because of non-steroidal anti-inflammatory drugs usage, and 40 patients were classified into 5 degrees by endoscopic findings. All patients were classified by CSI based on clinical symptoms and laboratory findings. Correlations among CSI, hospital stay, and endoscopic grade were analyzed. Results: The older patients (p=0.0018) and the patients with lower serum hemoglobin (p=0.0049), lower serum albumin (p


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