흰쥐의 외안부 풀리 평활근의 분포와 신경지배
(The) Distribution and Innervation of the Extraocular Pulley Smooth Muscle in the rat
흰쥐 외안부 풀리 평활근 신경지배;
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Extraocular rectus musle pulleys are important determinants of orbital biomechanics in animals including human. So, the author evaluated the structure, distribution and innervation of the extraocular pulley smooth muscle in the rat, a species with a less complex visuomotor repertoire than primates. The adult Sprague-Dawley rat was perfused transcardially with physiological saline followed by 4% paraformaldehyde. The orbits were removed en bloc, then paraffin processed and serially sectioned for Hematoxylin-Eosin and Masson's trichrome stain. The distribution and innervation of the extraocular pulley smooth muscle was confirmed by immunohistochemistry with human smooth muscle (SM) α-actin, tyrosine hydroxylase (TH) and neuronal nitric oxide synthase (nNOS). The author found that the pulley's structure consist of focal condensations of elastin and collagenous connective tissue in relationship to the rectus muscle in the equatorial Tenon's fascia. Especially, the pulley smooth muscles related to medial rectus muscle were immunostained to TH and nNOS suggesting dopaminergic innervation. The data suggest that the extraocular pulley smooth muscle in the rat orbit is innervated by dopaminergic and nitroxidergic system.