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Synthetic study and biological properties of phenyl pyrimido[1,2-c]thienopyrimidinone derivatives and their analogs 원문보기

  • 저자

    이혁주

  • 학위수여기관

    목원대학교 대학원

  • 학위구분

    국내석사

  • 학과

    화학과

  • 지도교수

    송양헌

  • 발행년도

    2014

  • 총페이지

    114 p.

  • 키워드

    phenyl pyrimido[1 2-c]thienopyrimidinone;

  • 언어

    kor

  • 원문 URL

    http://www.riss.kr/link?id=T13534575&outLink=K  

  • 초록

    According to recent studies, the compounds including 4H-pyrido[1,2-a]- pyrimidine-4-one in molecule show diverse pharmacological activities such as anti HIV-1 agent, antiplasmodial falcipain-2 inhibitor and metabotropic glutamate receptor 5(mGlu5). In this study, a new synthetic method for phenyl pyrimido- [1,2-c]thienopyrimidinone and its various derivatives derived from pyrimidinone was developed and their biological activities were evaluated.


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