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Studies on Effects of Increased Serum Creatinine Level in Latent Phase 원문보기

  • 저자

    MinwooLee

  • 학위수여기관

    고려대학교 대학원

  • 학위구분

    국내석사

  • 학과

    의생명융합과학과

  • 지도교수

    김성욱

  • 발행년도

    2014

  • 총페이지

    30 p.

  • 키워드

    Creatinine Latent phase Cesarean section Failure to progress;

  • 언어

    eng

  • 원문 URL

    http://www.riss.kr/link?id=T13541884&outLink=K  

  • 초록

    Background: The objective of this study was to evaluate the association between serum creatinine level in the latent phase of labor and risks of cesarean section due to failure to progress. Methods: Women admitted in latent phase, defined as contractions at less than 4cm cervical dilatation at 37 to 42 weeks, with a single gestation and vertex presentation were recruited. We enrolled both women who had vaginal deliveries and women who underwent cesarean section due to failure to progress. Failure to progress included both arrest of dilatation and arrest of descent. Serum creatinine levels were measured at admission. Women who initially had normal serum creatinine levels (less than 0.8 mg/dL) were included. Ultimately, we enrolled 203 women, 46 (%) of whom had a primary cesarean section due to failure to progress. Results: Women who had a cesarean delivery due to failure to progress had higher creatinine levels than women who had vaginal deliveries (0.55 ± 0.09 vs. 0.51 ± 0.10, p = 0.024). In multivariate logistic analysis controlling for age, gestational age, parity, cervical dilatation, neonatal sex, and birth weight, women with serum creatinine levels in the fourth quartile showed an increased risk for cesarean delivery due to failure to progress (odds ratio 3.20, 95% confidence interval 1.08-9.52) compared to women with serum creatinine levels in the first quartile. Conclusions: Increased serum creatinine level in the latent phase was associated with an increased risk of cesarean section due to failure to progress.


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