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Usefulness of contrast-enhanced ultrasonography as a planning modality for radiofrequecy alblation of hepatocellular carcinoma: comparison with gray-scale ultrasonography 원문보기

  • 저자

    김소희

  • 학위수여기관

    고려대학교 대학원

  • 학위구분

    국내석사

  • 학과

    의학과 영상의학전공

  • 지도교수

    최재웅

  • 발행년도

    2014

  • 총페이지

    iv, 34 p.

  • 키워드

    HCC + contrast-enhanced ultrasound;

  • 언어

    eng

  • 원문 URL

    http://www.riss.kr/link?id=T13541914&outLink=K  

  • 초록

    Purpose Radiofrequency ablation (RFA) is not feasible when hepatocellular carcinoma (HCC) is poorly defined or invisible on conventional gray-scale ultrasonography (GSUS). Recent introduction of contrast-enhanced ultrasonography (CEUS) help diagnose HCC by showing its typical enhancement pattern. The purpose of this study is to demonstrate the added value of CEUS as a RFA planning modality for HCC compared with conventional GSUS. Methods and Materials Total sixty-four HCCs from 57 patients (men:women=41:16; mean age, 62.6) who have undergone GSUS & CEUS for RFA planning on 2011 were retrospectively reviewed. Sonographic contrast agent was used for CEUS after conventional GSUS. Two radiologists reviewed the recorded images of GSUS and CEUS in consensus. On GSUS, the size, location, & echogenicity of each HCC were reviewed. Also the definition of HCC on GSUS was categorized to clearly-visible, equivocal, and invisible. HCC visible with typical enhancement pattern on CEUS were recorded. Results The mean size of HCCs was 1.8 cm (range, 0.9-4.8 cm). Among 64 HCCs, hyperechoic nodules were 11; isoechoic, 24; hypoechoic, 22; and mixed echogenicity, 7 on GSUS. Among the 24 isoechoic nodules, three nodules were clearly visible due to hypoechoic rim on GSUS, two were equivocal, and 19 were invisible. One hypoechoic nodule and two mixed nodule were equivocal on GSUS. Total 40 nodules were clearly visible, 5 were equivocal, and 19 were invisible. By performing CEUS, 11 out of 19 invisible, isoechoic nodules and 5 out of 5 equivocal nodules were identified. Forty out of 64 nodules were identified on GSUS, however 56 out of 64 nodules were identified by performing GSUS and CEUS (detection rate: 62.5% vs 87.5%, p-value


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