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韓國營養學會誌 = The Korean journal of nutrition. v.27 no.8, 1994년, pp.819 - 827   피인용횟수: 26

메밀급여가 Streptozotocin유발 당뇨쥐의 장기무게 및 당질과 지질대사에 미치는 영향
Effects of Buckwheat on Organ Weight, Glucose and Lipid Metabolism in Streptozotocin-Induced Diabetic Rats

이정선    (한림대학교 한국영양연구소  );
  • 초록

    The present study was undertaken to evaluate the effects of 50% buckwheat diet on the body weight, organ weight, urine albumin, urine glucose, plasma glucose and plasma lipid in normal rats and diabetic rats treated with streptozotocin(STZ). The food intake, body weight, the level of urine glucose in diabetic buckwheat groups were not significantly different with diabetic control group. The level of urine albumin was lower in raw and steam buckwheat group than in the diabetic control group. Compared to the normal control group, liver and kidney weights were heavier in the diabetic groups. Pancreas weight was heavier diabetic buckwheat groups than in normal and diabetic control groups. Fasting plasma glucose level of diabetic buckwheat groups significantly decreased by 18-37% compared with the diabetic control group. Plasma triglyceride level of diabetic buckwheat groups significantly decreased by 34-50% compared with the diabetic control group. Plasma total cholesterol level of diabetic buckwheat groups decreased by 15-27% compared with the diabetic control group. The level of HDL-cholesterol was not affected by buckwheat diet. These results indicate that buckwheat is an effective therapeutic regimen for the control of metabolic derangements in diabetics.


  • 주제어

    buckwheat .   diabetic rat .   plasma glucose .   plasma lipid.  

  • 이 논문을 인용한 문헌 (26)

    1. 1995. "Effects of Buckwheat Diet on Serum Glucose and Lipid Metabolism in NIDDM" 韓國營養學會誌 = The Korean journal of nutrition., 28(9): 809~816     
    2. 1996. "Effects of Buckwheat on the Activities of Pancreatic Digestive Enzymes in Streptozotocin-Induced Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 25(5): 831~838     
    3. 1996. "Effects of Raw Soy Flour and Magnesium on Serum Glucose and Lipid Metabolism in Streptozotocin-Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 25(6): 963~968     
    4. 1997. "The Effect of Trichosanithes kirilowii Max. Subfractions on the Insulin Activity in Streptozotocin Induced Diabetic Rats and Their Acute Toxicity" 韓國營養學會誌 = The Korean journal of nutrition., 30(1): 25~31     
    5. 1997. "Effects of Mushroom Protein -bound Polysaccharides on Blood Glucose Levels and Energy Metabolism in Streptozotocin-Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 30(7): 743~750     
    6. 1998. "Effects of Dietary Fiber Sourecs on Lipid Metabolism and Kidney Function in Rats Fed High Cholesterol Diet" 東아시아食生活學會誌 = Journal of the East Asian Society of Dietary Life, 8(2): 107~115     
    7. 1998. "Effect of Royal Jelly on Therapy and Prevention of Streptozotocin Induced Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 27(6): 1267~1272     
    8. 1998. "Effects of Raw Soy Flour(yellow and black) on Serum Protein Concentrations and Enzyme Activity in Streptozotocin-Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 27(4): 724~730     
    9. 1998. "Effect of Raw Soy Flour(yellow and black) on Serum Glucose and Lipid Concentration in Streptozotocin-induced Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 27(2): 313~318     
    10. 1998. "Effects of Silkworm Powder on Blood Glucose and Lipid Levels in NIDDM(Type II) Patients" 韓國營養學會誌 = The Korean journal of nutrition., 31(7): 1139~1150     
    11. 1998. "A Study of Folk Remedies in Type II Diabetic Patients" 韓國營養學會誌 = The Korean journal of nutrition., 31(7): 1151~1157     
    12. 1999. "Effects of Tea Fungus/Kombucha Beverage on Serum Protein Levels and Enzyme Activity in Streptozotocin-Induced Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 28(5): 1137~1143     
    13. 1999. "Effect of Tea Fungus/Kombucha Beverage on Lipid Metabolism in Streptozotocin-induced Diabetic Male Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 28(3): 613~618     
    14. 1999. "Noodle Making Characteristics of Buckwheat Composite Flours" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 28(2): 383~389     
    15. 1999. "Effects of Legume Supplementation on the Gastrointestinal Function and Diabetic Symptoms in Streptozotocin-Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 32(6): 617~627     
    16. 2000. "The Effect of BuOH Fraction of Polygonatum odoratum with Selenium on Blood Glucose Level and Lipid Peroxidation in Streptozotocin Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 33(7): 703~711     
    17. 2001. "The Effect of Each Fraction of Methanol Extract of Alisma canaliculatum on Blood Glucose Levels and Lipid Metabolism in Streptozotocin Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 34(6): 619~625     
    18. 2002. "Effects of Dietary Mushroom on Blood Glucose Levels, Lipid Concentrations and Glutathione Enzymes in Streptozotocin-Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 35(2): 183~191     
    19. 2002. "Effects of Tea Fungus/Kombucha Beverage on Lipid Metabolism and Protein Level in Diabetic Female Rats" 생명과학회지 = Journal of life science, 12(6): 661~668     
    20. 2003. "Effects of Edible and Medicinal Plants Intake on Blood Glucose, Glycogen and Protein Levels in Streptozotocin Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 36(10): 981~989     
    21. 2004. "Hypoglycemic and Antioxidative Effects of Dietary Sea-Tangle Extracts Supplementation in Streptozotocin-Induced Diabetic Rats" 韓國營養學會誌 = The Korean journal of nutrition., 37(1): 5~14     
    22. 2004. "Monitoring on the Tea with Steaming and Drying Process of Germinated Buckwheat" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 33(1): 212~217     
    23. 2004. "Dietary Effect of Hemicellulose from Shiitake Mushroom(Lentinus edodes) on Blood Glucose and Cholesterol Content in Rats" 東아시아食生活學會誌 = Journal of the East Asian Society of Dietary Life, 14(3): 243~250     
    24. Kim, Ji-Eun ; Joo, Sung-Il ; Seo, Ji-Hyun ; Lee, Sam-Pin 2009. "Antioxidant and α-Glucosidase Inhibitory Effect of Tartary Buckwheat Extract Obtained by the Treatment of Different Solvents and Enzymes" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 38(8): 989~995     
    25. Jung, Un-Ju ; Lee, Jeong-Sun ; Bok, Song-Hae ; Choi, Myung-Sook 2011. "Effects of Extracts of Persimmon Leaf, Buckwheat Leaf, and Chinese Matrimony Vine Leaf on Body Fat and Lipid Metabolism in Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 40(9): 1215~1226     
    26. Han, Hye Kyoung 2012. "Effect of Artemisia iwayomogi Ethanol Extract on Hypoglycemic and Antioxidant Activities in Diabetic Rats" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 41(12): 1716~1726     

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  • 이정선 (15)

    1. 1991 "수유기간의 경과에 따른 한국인 인유의 칼슘 및 인 함량의 변화" 韓國營養學會誌 = The Korean journal of nutrition. 24 (3): 206~218    
    2. 1991 "한국산 야생 및 재배동백종자의 지방산 조성" 한국유화학회지 = Journal of oil & applied science 8 (1): 51~54    
    3. 1995 "메밀의 다당류 추출과 구성당 분석" 한국식품과학회지 = Korean journal of food science and technology 27 (6): 860~865    
    4. 1995 "In vitro에서 메밀 다당분획이 casein 가수분해에 미치는 영향" 한국식품과학회지 = Korean journal of food science and technology 27 (6): 866~870    
    5. 1995 "메밀식이가 제 2형 당뇨환자의 혈당과 혈중지질 대사에 미치는 영향" 韓國營養學會誌 = The Korean journal of nutrition. 28 (9): 809~816    
    6. 1996 "In vitro에서 메밀의 다당류가 소화효소 활성에 미치는 영향" 한국식품과학회지 = Korean journal of food science and technology 28 (1): 34~39    
    7. 1996 "강원도 화천지역에 거주하는 40대 이상 주민의 혈청지질 농도 및 이와 관련된 요인 분석" 韓國營養學會誌 = The Korean journal of nutrition. 29 (9): 1035~1041    
    8. 1996 "메밀급여가 Streptozotocin 유발 당뇨쥐의 췌장 소화효소 활성에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 25 (5): 831~838    
    9. 1997 "치커리추출물 첨가가 in vitro 전분가수분해율 및 정상성인의 혈당반응에 미치는 영향" 한국식품과학회지 = Korean journal of food science and technology 29 (6): 1295~1303    
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