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韓國營養學會誌 = The Korean journal of nutrition. v.27 no.2, 1994년, pp.127 - 140   피인용횟수: 1

식이 Cholesterol의 수준에 따라 우유가 흰쥐의 Cholesterol 대사에 미치는 영향
Effect of Milk on Cholesterol Metabolism of Rats with Different Levels of Dietary Cholesterol

최명숙    (경북대학교 식품영양학과  );
  • 초록

    The effect of milk in low and high cholesterol diet was invesigated on serum cholesterol metabolism and lipid contents of serum, aorta, liver of rats. Weanling male Sprague-Dawley rats were divided into low(0.01% w/w) and high(1.01% w/w) cholesterol-diets groups. Low cholesterol groups subdivided into four groups ; control group was given water and three milk groups were given low heat milk(LM), ultra-high heat milk(HM), and powder milk(PM), respectivily, instead of water. High cholesterol groups were consisted of three groups ; control, LM, and HM groups. After feeding these experimental diets for six weeks, lipid levels were measured in serum and tissure and dried feces were analyzed for neutral and acidic sterols. Results obtained from this study are as follows : 1) Nutrient intakes, body weight gains and aorta weights did not differ among groups, but liver weights were higher in high cholesterol fed rats than low cholesterol fed rats. 2) Serum protein contents were increased independently by intakes of high cholesterol and milk. 3) Serum total cholesterol and triglyceride levels were increased but phospholipid levels and HDL-cholesterol/total-cholesterol ratios were decreased by high cholesterol in diet. And milk supplementation decreased serum total cholesterol and triglyceride levels but increased phospholipid levels and HDL-cholesterol/total-cholesterol ratios. 4) Contents of cholesterol and triglyceride in aorta and liver were elevated by dietary high cholesterol and lowered by consumption of all three types of milk. 5) Levels of cholesterol and triglyceride among serum, aorta and liver were highly correlated (r=0.7-0.9, p


  • 주제어

    low cholesterol diet .   high cholesterol diet .   fecal sterol .   tissue cholesterol .   serum cholesterol.  

  • 이 논문을 인용한 문헌 (1)

    1. 1995. "Effects of Duck Oil on Serum and Organ Lipid Composition in Mature Rats" 한국영양식량학회지, 24(6): 874~879     

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  • 최명숙 (42)

    1. 1994 "A Growth-Stimulating Protein in Cow's Milk" 東아시아食生活學會誌 = Journal of the East Asian Society of Dietary Life 4 (3): 59~65    
    2. 1997 "Simple Iysine sensing system using $CO_{2}$ electrode and enzyme immobilized to CNBr-activated sepharose 4B" 센서학회지 = Journal of the Korean Sensors Society 6 (6): 437~444    
    3. 1998 "토종홍화씨의 급여가 실험동물의 늑골골절 회복중 골조직에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 27 (4): 698~704    
    4. 1998 "한국산 홍화씨분말 보충식이의 급여가 골절된 흰쥐의 골대사지표에 미치는 영향" 韓國營養學會誌 = The Korean journal of nutrition. 31 (6): 1049~1056    
    5. 1999 "한국산과 중국산 홍화종실의 화학적 성분 비교" 한국식품과학회지 = Korean journal of food science and technology 31 (4): 912~918    
    6. 1999 "시험관법에의한 식물열수추출물의 3-Hydroxy-3-Methylglutaryl CoA Reductase 및 Acyl-CoA:Cholesterol Acyltransferase 활성 저해도 측정" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 28 (4): 958~962    
    7. 1999 "홍화종실분말 식이가 고지방-고콜레스테롤섭취 흰쥐의 지질대사에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 28 (3): 625~631    
    8. 2000 "볶음 홍화씨 분말첨가 식빵의 품질특성" 농산물저장유통학회지 = Journal of the Korean society of post-harvest science & technology of agricultural products 7 (1): 80~83    
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