본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

생약학회지 v.26 no.3, 1995년, pp.265 - 272  

Inhibitory Effects of Herbal Medicines on Hyaluronidase Activity

Kim, Young-Soo   (College of Pharmacy, Chungbuk National UniversityUU0001309  ); Noh, Young-Kyun   (College of Pharmacy, Chungbuk National UniversityUU0001309  ); Lee, Gyeong-Im   (College of Pharmacy, Chungbuk National UniversityUU0001309  ); Kim, Young-Ki   (College of Pharmacy, Chungbuk National UniversityUU0001309  ); Lee, Kyong-Soon   (College of Pharmacy, Chungbuk National UniversityUU0001309  ); Min, Kyung-Rak   (College of Pharmacy, Chungbuk National UniversityUU0001309  );
  • 초록

    Inhibitory effects of 130 medicinal plants on hyaluronidase activity were analyzed. The medicinal plants are clinically used as herbal medicines for korean traditional prescriptions. Six out of the 130 herbal medicines exhibited more than 50% of inhibition on hyaluronidase activity by their total methanol extracts with 5mg/ml as a final concentration. The active total methanol extracts were prepared from cortex of Acantbopanax gracilistylus, lignum of Caesalpinia sappan, radix of Glycyrrhiza uralensis, radicis cortex of Morus alba, herba of Prunella vulgaris, and radix of Sanguisorba officinalis. These active total methanol extracts were sequentially fractionated with dichloromethane, ethyl acetate, n-butanol, and then water. Among the solvent-fractionated extracts, the butanol fractions of Acantbopanax gracilistylus and Glycyrrhiza uralensis with 1 mg/ml as the final concentration exhibited more than 50% of inhibition on hyaluronidase activity, and the other fractions with the same concentration did less than 20% of inhibition.


  • 주제어

    Hyaluronidase activity .   Acanthopanax gracilistylus .   Caesalpinia sappan .   Glycyrrhiza uralensis .   Morus alba .   Prunella vulgaris .   Sanguisorba officinalis.  

 저자의 다른 논문

  • Kim , Young-Soo (52)

    1. 1989 "5-Lipoxygenase의 활성과 Leukotriene $B_4$ 생합성 억제물질" 약학회지 = Yakhak hoeji 33 (6): 319~323    
    2. 1990 "흰쥐의 다리종양에서 발현된 케이라스 암유전자" 한국생화학회지 23 (2): 185~189    
    3. 1991 "Pseudomonas putida의 Catechol 2,3-dioxygenase 유전자의 클로닝" Korean journal of microbiology = 미생물학회지 29 (3): 155~159    
    4. 1992 "Molecular Cloning and M13 Subcloning of Genes Encoding Catechol Dioxygenases" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 15 (1): 48~51    
    5. 1992 "Cloning and Overexpression of Methylcatechol 2, 3-Dioxygenase Gene from Toluene-Degrading Pseudomonas putida mt-2(pWWO)" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 15 (4): 360~364    
    6. 1995 "Effect of Temperature on Persistence of Recombinant Plasmid pCU103 in Different Waters" The journal of microbiology 33 (3): 178~183    
    7. 1996 "Inhibitory Effects of Triterpenoids on Interleukin-8/CINC-1 Induction in LPS-Stimulated Rat Peritoneal Macrophages" Natural product sciences 2 (1): 48~55    
    8. 1996 "Inhibitory Effects of Herbal Extracts on Cyclooxygenase Activity of Prostaglandin $H_2$ Synthase from Sheep Seminal Vesicle" Natural product sciences 2 (1): 56~74    
    9. 1996 "Extracellular DNAs Released form the Genetically Engineered E. coli CU103 During Growth in Different Liquid Media" The journal of microbiology 34 (2): 144~150    
    10. 1996 "Cloning and Expression of Pseudomonas cepacia catB Gene in Pseudomonas putida" The journal of microbiology 34 (4): 334~340    
  • Lee, Gyeong-Im (2)

  • Kim, Young-Ki (2)

  • 이경순 (67)

  • 민경락 (18)

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • NDSL :
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기