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The journal of microbiology v.35 no.2, 1997년, pp.92 - 96  

Characterization of a new staphylococcal site-specific recombinase sin and genetic organization of its flanking region

Yong, Jun-Hyong    (Kangwon National University   ); Kim, Young-Sun    (Kangwon National University   ); Byeon, Woo-Hyeon    (Kangwon National University  );
  • 초록

    A new site-specific recombinase sin, as a component of a putatie transposon has been cloned and its base sequence has been determined. The proposed sin shows a hish degree of homology with pI9789-sin and pSK1-sin. There is a large (16 bp) inverted repeat downstream of proposed sin and the postulate dhelix-turn-helix motif is located at the extreme C-terminus of the poposed Sin. The transposase gene (tnpA) and .betha.-lactamase gene (blaZ) are located upstream of sin and arsenate reductase gene (arsC) and arsenic efflux pump protein gene (ars B) are downstream. This genetic arrangement seems to be a part of a new putative transposon because there is no known transposon with a gene arrangement of tnpA-blaZ-sin-arsC.


  • 주제어

    DNA invertase .   sin .   site-specific recombinase .   staphylococcal transposon.  

  • 참고문헌 (19)

    1. Rearrangement in the staphylococcal β-lactamase encoding plasmid, pIP1066, including a DNA inversion that generates two alternative transposon , Derbise, A.;K.G. Dyke;N. el Solh , Mol. Microbiol. / v.17,pp.769-779,
    2. Structural and functional requirements for IS 50-specific recombination , Chung, J.H. , Ph. D. thesis. Seoul National University / v.,pp.,
    3. Characterization of sin, a potential recombinase-encoding gene from Staphylococcus aureus , Paulsen, I.T.;M.T. Gillespie;T.G. Littlejohn;O. Hanvivatvong;S. Rowland;K.G.H. Dyke;R. A. Skurray , Gene. / v.141,pp.109-114,
    4. Regulation and expression of arsenic resistance operon From Staphylococcus aureus plasmid pI258 , Ji, G.;S. Silver , J. Bacteriol. / v.174,pp.3684-3694,
    5. Genes involved in the regulation of β-lactamase production in Enterococci and Staphylococci , Zscheck, K.K.;B.E. Murray , Anti. Agent. Chem. / v.37,pp.1966-1970,
    6. Tn552, a novel transposable element from Staphylococcus aureus , Rowland, S.J.;K.G.H. Dyke , Mol. Micro. / v.4,pp.961-975,
    7. Plasmid-borne cadmium resistance genes in Listeria monocytogenes are present on Tn5422, a novel transposon closely related to Tn917 , Lebrun, M.;A. Audurier;P. Cossart , J. Bacteriol. / v.176,pp.3049-3061,
    8. Tn552 transposase purification and in vitro activities , Rowland, S.J.;D.J. Sherratt;W.M. Stark;M.R. Boocock , EMBO J. / v.14,pp.196-205,
    9. Genetic organization of an inducible β-lactamase gene isolated from chromosomal DNA of Staphylococcus aureus , Kim, Y.S.;K.I. Min;W.-H. Byeon , Kor. Jour. Microbiol. / v.32,pp.20-27,
         
    10. Protoplast transformation of Staphylococcus carnosus by plasmid DNA , Gotz, F.;B. Kreutz;K.H. Schleifer , Mol. Gen. Genet. / v.189,pp.340-342,
    11. Interaction of the chromosomal Tn551 with two thermosensitive derivatives, pS1 and pδD, of plasmid pI9789 in Staphylococcus aureus , Sohail, M.;M. Oldridge;K.G. Dyke , FEMS Mocrobiol Lett. / v.127,pp.165-170,
    12. DNA sequence organization of IS10-right of Tn10 and comparison with IS-left , Halling, S.M.;R.W. Simons;J.C. Way;R.B. Walsh;N. Klckner , Pro. Natl. Acad. Sci. / v.79,pp.2608-2612,
    13. Site-specific recA-independent recombination between bacterial plasmid: involvement of palindromes at the recombinational loci , Kopecko, D.J.;S.N. Cohen , Pro. Natl. Acad. Sci. / v.72,pp.1373-1377,
    14. Sequence analysis of the β-lactamase repressor from Staphylococcus aureus and hybridization studies β-lactamase-producing isolates of Escherichia faecalis , Smith, M.C.;E.M. Barbara , Anti. Agent. Chem. / v.36,pp.2265-2269,
    15. Characterization of the staphylococcal β-lactamase transposon Tn552 , Rowland, S.J.;K. G.H. Dyke , EMBO. J. / v.8,pp.2761-2773,
    16. Sequencing with chain termination inhibitors , Sanger, F.;S. Nicklen;A.R. Coulson , Pro. Natl. Acad. Sci. / v.74,pp.5463-5467,
    17. Transposition of R factor genes to bacteriophage λ , Berg, D.E.;J. Davies;B. Allet;J.D. Rochaix , Proc. Natl. Acad. Sci. / v.72,pp.3628-3632,
    18. Bacterial Transposons , Bennett, P.;J. Scaife(ed.);D. Leach(ed.);A. Galizzi(ed.) , Getics of Bacteria / v.,pp.97-115,
    19. Nucleotide sequence analysis of IS256 from the Staphylococcus aureus gentamycin-tobramycin-kanamycin-resistance transposon Tn4001 , Byrne, M.E.;Rouch, D.A.;R.A. Skurray , Gene / v.81,pp.361-367,

 저자의 다른 논문

  • 김영선 (3)

    1. 1985 "Staphylococcus aureus의 항생제 내성 plasmid에 관한 연구" Korean journal of microbiology = 미생물학회지 23 (4): 282~290    
    2. 1986 "Staphylococcus aureus에서 분리된 plasmid상의 항생물질 저항성 인자에 관한 연구 : Chloramphenicol 저항성 인자의 클로닝" Korean journal of microbiology = 미생물학회지 24 (4): 341~351    
    3. 1994 "Staphylococcus aureus에서 분리된 유발성 ${\beta}$-Lactamase 유전자의 유전적 구성" Korean journal of microbiology = 미생물학회지 32 (1): 20~27    
  • Byeon, Woo-Hyeon (11)

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