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韓國營養學會誌 = The Korean journal of nutrition. v.30 no.10, 1997년, pp.1153 - 1159   피인용횟수: 1

비타민 E 보강식이가 KK 마우스에서 지질과산화물과 신장 항산화계 효소 활성도에 미치는 영향
Effects of Vitamin E Supplementation on Lipid Persoxides and Renal Antioxidative Enzyme Activities in KK Mice

안현숙    (서울대학교 식품영양학과  );
  • 초록

    We investigated the effects of vitamin E supplementation on lipid peroxidation and on the activities of antioxidative enzymes in kidney of KK mice of various age and duration of diabetes. Weaned KK mice were fed high fat a diet containing 20% corn oil(wt/wt), and were sacrificed at 4, 6, and 9 months of age. The high vitamin E diet consisted of the high fat diet supplemented with an excessive amount of dl- $\alpha$ -tocopheryl acetate (2080 IU/kg diet) . In the diabetic groups, we found an increase in lipofuscin and decrease in antioxidative enzyme activities with aging. Treatment with vitamin E did not modify the level of fasting blood glucose. However, a significant decrease in lipofuscin and increase in antioxidative enzyme acitvities were observed in diabetic mice.


  • 주제어

    high vitamin E supplementation .   KK mice .   antioxidative enzymes .   lipid peroxidation of kidney.  

  • 참고문헌 (30)

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  • 이 논문을 인용한 문헌 (1)

    1. 1999. "Effects of Antioxidant Vitamins Supplementation on Antioxidative Status and Plasma Lipid Profile in Korean NIDDM Patients" 韓國營養學會誌 = The Korean journal of nutrition., 32(7): 775~780     

 저자의 다른 논문

  • 안현숙 (4)

    1. 1992 "식이 중 지방과 탄수화물 비율이 쥐 간이 Glucokinase의 활성도에 미치는 영향" 韓國營養學會誌 = The Korean journal of nutrition. 25 (2): 109~115    
    2. 1997 "비타민 E 보강식이가 당뇨 KK마우스에서 당화단백질 생성에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 26 (5): 914~919    
    3. 1998 "비타민 E 보강식이가 KK마우스에서 간조직의 항산화계 효소 활성도에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 27 (1): 149~156    
    4. 1998 "당뇨 KK마우스에서 비타민 E 보강식이가 신장 당화단백질 생성에 미치는 영향" 韓國營養學會誌 = The Korean journal of nutrition. 31 (6): 1024~1030    

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