본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

韓國營養學會誌 = The Korean journal of nutrition. v.30 no.8, 1997년, pp.976 - 986   피인용횟수: 3

관상동맥질환자에서 병변의 협착정도에 따른 일반영양소 및 개별지방산의 섭취양상
Nutrients and Individual Fatty Acids Intake Patterns in the Coronary Artery Disease Patients with Different Degrees of Stenosis

김수연    (연세대학교 식품영양학과  );
  • 초록

    Coronary artery disease (CAD) such as angina pectoris and myocardial infarction(MI) have been considered the major cause of death for decaddes . THeir incidence and prevalence are still increasing . Numerous studies have been done on the risk factor analysis of CAD in Western countries. Since the diet in Western countries is different from that in Korea it is difficult to assume that the Korean diet has the same effects as its western counterpeart on the development of CAD . THus the gudidelines for the Western CAD patients can no totally be applied to Koreans. This study was conducted to investigate the relationship between diet and CAD in Koreans. Subjects were comprised of patients admitted to the hospital for chest pain with poxxilbe CAD (men 129, women 65) . They were divided into the following three groups according to angiographic results ; angiogrphically normal coronary artery group (control), single vessel disease group(SVD) and multiple vessel disease group (MVD) . Intakes of dietary fatty acids and other nutrients were assessed by the semiquantitative food frequency method. Blood was also obtained from subjects for serum lipid analysis. Serum lipid profiles of men were clearly different form those of women. For men, serum choesterol levels (or LDL or LDL/HDL) seemed to be higher in the MVD group compared to the control and SVD groups, while TG level was significantly higher in the MVD group for women. Both men and women showed significantly higher caloric , fiber and vitamins C and A intakes in the MVD group than in the other two groups. Higher caloric intakes was due to higher intakes of carbohydrate and protein rather than fat intake. In terms of fatty acids intake, there were no significant differences among the three groups . Smoking seemed to have great effect on eating patterns in CAD patients. Smokers and ex-smokers showed significantly higher intakes of most nutrients including individual fatty acids that non-smokers. The results of stepwise regression showed that moderate alcohol intake decreases LDL levels and increases HDL levels and smoking seems to lowe HDL levels in CAD patients.


  • 주제어

    coronary artery disease .   food frequency questionaire .   dietary fatty acids .   dsrum lipid profile.  

  • 참고문헌 (56)

    1. Frequently consumed food items of Korean from National Food Survey of Korea , 문현경 , 서울대학교 workshop / v.,pp.,
    2. 이양자;이희자;오경원 , 상용식품의 지방산조성표 / v.,pp.,
    3. Identifying adults at increased risk of coronary disease. How Well do the current cholesterol guidelines work , Grover,S.A.;Coupal,L.;Hu,X.P. , J Am Med Assoc / v.274,pp.801-814,
    4. Triglycerides : A risk factor for coronary heart disease , Davignon,J.;Cohn,J.S. , Atherosclerosis / v.124,pp.S57-S64,
    5. Plasma levels of antioxidant vitamins in relation to ischemic heart disease and cancer , Gey,K.F.;Brubacher,G.B.;Stahelin,H.B. , Am J Clin Nutr / v.45,pp.1368-1377,
    6. Combination treatment with vitamin E and C in experimental myocardial infarction in pigs , Kleir,H.H.;Pich,S.;Lindert,S.;Nelendahl,K.;Nelendahl,K.;Niedmgnn,P.;Kneuzer,H. , Am Hear J / v.118,pp.667-673,
    7. 성인의 개별적인 지방산 섭취양상과 혈청 지질농도와의 관계에 대한 연구 , 오경원;이상인;송경순;남정모;김영옥;이양자 , 한국지질학회지 / v.5,pp.167-181,
    8. Coronary angiographic features in 2234 patients with clinical suspicion of coronary heart disease without modifiable risk factors , Loaldi,A.;Annoni,L.;Apostolo,A.;Grancini,L.;Ravagnani,P.;Guazzi,M. , Japanese Heart J / v.34,pp.11-21,
    9. Effects of the individual saturated fatty acids on serum lipids and lipoprotein concentrations , Mensink,R.P. , Am J Clin Nutr / v.57,pp.711S,
    10. Cholesterol and coronary heart disease. Predicting risks by levels and ratios , Kinosian,B.;Click,H.;Garland,G. , Ann Intern Med / v.121,pp.641-654,
    11. Oat products an lipid lowering : A meta-analysis , Ripsin,C.M.;Keenan,J.M.;Jacobs,J.D.R. , JAMA / v.267,pp.3317-3325,
    12. Beyond cholesterol modification of low-density lipoprotein that increase its atherogenecity , Steinber,D.;Parthasarathy,S.;Carew,T.E.;Khoo,J.C.;Witztum,J.L. , N Engl J Med / v.320,pp.915-924,
    13. 한국인의 고지혈증에 관한 연구(Ⅰ), 정상인 및 고혈압증에 있어서의 고지혈증 , 손이식 , 대한의협 / v.18,pp.345,
    14. 관상동맥질환 환자에서의 식습관이 혈청 지질 농도 및 관상동맥질환에 미치는 영향 , 임현숙;백인경;이호선;이영준;정남식;조승연;김성순 , 한국지질학회지 / v.5,pp.71-83,
    15. Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men , Rimm,E.B.;Ascherio,A.;Giovannucci,E.;Spiegelman,D.;Stampfer,M.J.;Willett,W.C. , JAMA / v.275,pp.447-451,
    16. Ten year incidence of coronary heart disease in the Honolulu heart program : Relationship to nutrient intake , McGree,D.L.;Reed,D.M.;Yano,K. , Am J Epidemiol / v.119,pp.667-676,
    17. 한국 성인의 연령에 따른 혈청 지질 분포형태와 비만도 및 고혈압과의 관계 , 박연희;이종순;이양자 , 한국지질학회지 / v.3,pp.165-180,
    18. Hypercholesterolemia and coronary risk in the elderly. The Framingham Study , Wilson,P.W.F.;Kannel,W.B. , Am J Geriatr Cardiiol / v.2,pp.52-66,
    19. Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease(the PROCAM experience) , Assmann,M.D.;Schulte,H. , Am J Cardiol / v.70,pp.733-737,
    20. Changes in total serum cholesterol and other risk factors of cardiovascular disease in Japan , Okayama,A.;Ueshima,H.;Marmot,M.;Nakamura,M.;Kita,Y.;Yamakawa,M. , Int'l J Epidemiology / v.22,pp.1038-1047,
    21. Diet and heart disease risk factors in adult American men and women : The Framingham offspring-spouse nutrition studies , Posner,B.M.;Cupples,L.A.;Franz,M.M.;Gagnon,D.R. , Int'l J Epidemiol / v.22,pp.1014-1025,
    22. Ten-year retrospective on the antioxidant hypothesis of arteriosclerosis : Threshold plasma levels of antioxidant micronutrients related to minimum cardiovascular risk , Gey,K.F. , J Nutr Biochem / v.6,pp.206-236,
    23. TG, HDL and Coronary Heart Disease , National Institute of Health , Consensus Development Conference, Clinical Courier / v.10,pp.1-8,
    24. Alcohol intake and the risk of cardiovascular disease in middle-aged Japanese men , Iso,H.;Kitamura,A.;Shimamoto,T.;Sankai,T.;Naito,Y.;Sato,S.;Kiyama,M.;Iida,M.;Komachi,Y. , Stroke / v.26,pp.767-773,
    25. Incidence of coronary heart disease and lipoprotein cholesterol levels , Castelli,W.P.;Garrison,R.T.;Wilson,P.W.F. , J Am Med Assoc / v.256,pp.2835-2841,
    26. Effect of Dietary stearic acid on plasma cholesterol and lipoprotein levels , Bonanome,A.;Grundy,S.M. , New Engl J Med / v.318,pp.1244,
    27. Overview : Dietary approaches for reducing cardiovascular disease risks , Dwyer,J. , J Nutr / v.125,pp.656S-665S,
    28. Smoking status and dietary fats , Strickland,D.;Graves,K.;Lando,H. , Preventive Medicine / v.21,pp.228-236,
    29. Coronary heart disease, serum lipids, platelets and dietary fish in two communities in northern Norway , Simonsen,T.;Vartun,A.;Lyngmo,V.;Nordoy,A. , Acta Med Scand / v.222,pp.237-245,
    30. 한국식품공업협회 식품연구소 , 식품섭취 실태조사를 위한 식품 및 음식의 눈대중량 / v.,pp.,
    31. Estimation of the concentration of low density llipoprotein cholesterol in plasma without use of the preparative ultracentrifuge , Friedewald,W.T.;Levy,R.I.;Fredrickson,D.S. , Clin Chem / v.18,pp.499-502,
    32. Diet and incident ischaemic heart disease : The Caerphilly Study , Fehily,A.M.;Yarnell,J.W.G.;Sweetnam,P.M.;Elwood,P.C. , Br J Nutr / v.69,pp.303-314,
    33. Cigarette smoking, polyunsaturated fats and coronary heart disease , Thompson,R.L.;Pyke,S.;Scott,E.A.;Thompson,S.G.;Wood,D.A. , Ann NY Acad Sci / v.686,pp.130-138,
    34. 한국인의 고콜레스테롤혈증과 영양 , 이양자 , 한국지질학회지 / v.1,pp.111-122,
    35. Plasma triglyceride and high density lipoprotein cholesterol as predictors of ischaemic heart disease in British men , Bainton,D.;Miller,N.E.;Bolton,C.H. , Br Heart J / v.68,pp.60-66,
    36. Lipids, risk factors and ischaemic heart disease , Castelli,W.P. , Atherosclerosis / v.124,pp.S1-S9,
    37. Changing trends in dietary habits and cardiovascular disease in Japan : An overview , Goto,Y. , Nutr Rev / v.50,pp.398-401,
    38. 농촌진흥청 농촌 영양개선 연구원 , 식품분석표(제 5 개정판) / v.,pp.,
    39. Triglyceride levels and the risk of coronary artery disease : A view from Australia , Simons,L.A. , Am J Cardiol / v.70,pp.14H-18H,
    40. 대한예방의학회 , 건강통계 자료수집 및 측정의 표준화 연구 / v.,pp.,
    41. 정상 한국인의 혈중지질 분포와 영향을 주는 요인에 관한 연구 , 대한순환기학회 , 대한순환기학회, 혈중 지질공동연구 모임 / v.,pp.,
    42. Atherogenic lipoprotein phenotype : A proposed genetic marker for coronary heart disease risk , Austin,M.A.;King,M.C.;Vranizan,K.M.;Krauss,R.M. , Circulation / v.82,pp.495-506,
    43. Regional obesity and risk of cardiovascular disease : The Framingham study , Kannel,W.B.;Cupples,L.A.;Ramaswami,R.;Stokes,Ⅲ.J.;Kroger,B.E.;Higgins,M. , J Clin Epidemiol / v.44,pp.183-190,
    44. 허혈성심질환에서의 항산화영양소 상태와 혈소판 항산화계효소 활성에 관한 연구 , 최영선;이난희;조성희;배복선;박의현;임정교 , 한국영양학회지 / v.29,pp.223-231,
         
    45. Hypocholesterolemic effects of a dietary fiber supplement , Hunninghake,D.B.;Miller,V.T.;Larosa,J.C. , Am J Clin Nutr / v.59,pp.1050-1054,
    46. Secular trends in diet and risk factors for cardiovascular disease : The Framingham Study , Posner,B.M.;Franz,M.M.;Quatromoni,P.A.;Gagnon,D.R.;Sytkowski,P.A.;D'agostino,R.B.;Cupples,L.A. , J Am Diet Assoc / v.95,pp.171-179,
    47. Effects of serum lipid levels on restenosis after coronary angioplasty , Reis,G.J.;Kuntz,R.E.;Silverman,D.I.;Pasternak,R.C. , Am J Cardiol / v.68,pp.1431-1447,
    48. Summary estimates of cholesterol used to predict coronary heart disease , Castelli,W.P.;Abbott,R.D.;McNamara,P.M. , Circulation / v.67,pp.4-10,
    49. An Epidemiological study of cardiovascular and cardiopulmonary disease risk factors in four populations in the People's Republic of China , PRC-USA. Research group , Circulation / v.85,pp.1083-1096,
    50. 보건사회부 , 국민영양조사보고서 / v.,pp.,
    51. Cadiovascular disease : Specialized diagnostic procedures , Wyngaarden,J.B.;Smith,L.H. , Cecil Text book of Medicine(17th ed.) / v.,pp.186,
    52. High density lipoprotein as a protective factor against coronary heart disease , Gordon,T.;Castelli,W.P.;Hjortland,M.C.;Kannel,W.B.;Dawber,T.R. , Am J Med / v.2,pp.707-713,
    53. 통계청 , 사망통계연보 / v.,pp.,
    54. 일부 농촌지역 노인들의 영양상태에 관한 연구 , 서정숙;이은화;모수미 , 한국영양식량학회지 / v.11,pp.7-13,
    55. Dose recent alcohol comsumption reduce the risk of acute myocardial infarction and coronary death in regular drinkers? , Rodney,J.;Scragg,R.;Beaglehole,R. , Am J Epidemio / v.136,pp.819-824,
    56. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology , Gey,K.F.;Puska,P.;Jordan,P.;Moser,U. , Am J Clin Nutr / v.53,pp.326S-334S,
  • 이 논문을 인용한 문헌 (3)

    1. 1999. "Daily Kimchi Consumption and Its Hypolipidemic Effect in Middle-Aged Men" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 28(5): 1144~1150     
    2. 1999. "Serum Fatty Acids in Patients with Angiographically-Documented Coronary Artery Disease" 韓國營養學會誌 = The Korean journal of nutrition., 32(2): 166~174     
    3. 2001. "A Study on Dietary Intake Pattern and Risk Factors of Atherosclersis in Korean healthy Adults by Dietary Survey" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 30(1): 168~174     

 저자의 다른 논문

  • 김수연 (18)

    1. 1996 "한국인의 지방산 섭취현황 및 개선방향" 식품산업과 영양 = Food industry and nutrition 1 (2): 19~22    
    2. 1999 "관상동맥질환자의 혈청 지방산 조성에 관한 연구" 韓國營養學會誌 = The Korean journal of nutrition. 32 (2): 166~174    
    3. 2001 "식이지방산 조성 및 비타민 E의 보충이 제 2 세대 흰 쥐 뇌조직의 항산화 체계에 미치는 영향" 韓國營養學會誌 = The Korean journal of nutrition. 34 (1): 14~22    
    4. 2002 "일부여대생의 혈장 호모시스테인 함량과 비타민 $B_6, B_12$ 및 엽산 영양상태" 韓國營養學會誌 = The Korean journal of nutrition. 35 (1): 37~44    
    5. 2002 "지방산 및 비타민 E 보충 식이가 제2세대 흰쥐 간조직과 혈청의 항산화체계에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 31 (2): 257~262    
    6. 2002 "한국인 백내장환자의 항산화 체계에 관한 연구" 韓國營養學會誌 = The Korean journal of nutrition. 35 (2): 229~236    
    7. 2002 "Correlations between the Fatty Acid Composition of Serum Phospholipids and Blood Pressure" Nutritional sciences 5 (2): 68~74    
    8. 2002 "Effects of Fatty Acids and Vitamin E Supplementation on Behavioral Development of the Second Generation Rat" Nutraceuticals and food 7 (3): 265~272    
    9. 2003 "콩 단백 성분 및 연령이 암컷 흰쥐의 혈장 지질 농도와 인지질 지방산 패턴에 미치는 영향" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 32 (2): 269~277    
    10. 2005 "케일녹즙 분말식이가 흰쥐의 혈중 지질, 엽산 및 호모시스테인 수준에 미치는 효과" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition 34 (8): 1175~1181    

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • NDSL :
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기