Immunostimulating Activity of Polysaccharides from Mycelia of Phellinus linteus Grown under Different Culture Conditions
Polysaccharides were extracted from mycelia of Phellinus linteus grown under different culture conditions. The in vitro immunostimulating activity was measured by plaque-forming cell (PFC) assay. The activity of the polysaccharides was different from that of mycelia from which was extracted. The number of PFC's ranged from 40 to 600 depending on the media. When P. linteus was cultured on a medium with mannose or starch as a sole carbon source, the fungus produced polysaccharide with the highest activity of 960 PFC. Activity was therefore increased by $50%$ compared with polysaccharide which was extracted from mycelia grown on medium with glucose. pH had little effect on the change in activity. All polysaccharides on media with different pH stimulated about 600 PFC. These results suggest that activity could be increased by polysaccharide modification through changes in physiological conditions.
이 논문을 인용한 문헌 (13)
- Kweon, Mee-Hyang ; Jang, Hyo ; Lim, Wang-Jin ; Chang, Hyo-Ihl ; Kim, Chan-Wha ; Yang, Han-Chul ; Hwang, Han-Joon ; Sung, Ha-Chin 1999. "Anti-Complementary Properties of Polysaccharides Isolated from Fruit Bodies of Mushroom Pleurotus ostreatus" Journal of microbiology and biotechnology, 9(4): 450~456
- Park, Sang-Shin ; Hwang, Soo-Myung 1999. "Purification and Characterization of Iron-Containing Superoxide Dismutase from Lentinus edodes" Journal of microbiology and biotechnology, 9(6): 854~860
- Shon, Yun-Hee ; Lee, Jae-Sung ; Lee, Hang-Woo ; Nam, Kyung-Soo 1999. "Antimutagenic Potential of Phellinus igniarius" Journal of microbiology and biotechnology, 9(4): 525~528
- Yun, Bong-Sik ; Lee, In-Kyoung ; Kim, Jong-Pyung ; Yoo, Ick-Dong 2000. "Two p-Terphenyls from Mushroom Paxillus panuoides with Free Radical Scavenging Activity" Journal of microbiology and biotechnology, 10(2): 233~237
- Kweon, Mee-Hyang ; Lim, Wang-Jin ; Yang, Han-Chul ; Sung, Ha-Chin 2000. "Characterization of Two Glucans Activating an Alternative Complement Pathway from the Fruiting Bodies of Mushroom Pleurotus ostreatus" Journal of microbiology and biotechnology, 10(2): 267~271
- Bae, Jun-Tae ; Sinha, Jayanta ; Park, Jong-Pil ; Song, Chi-Hyun ; Yun, Jong-Won 2000. "Optimazation of Submerged Culture Conditions for Exo-Biopolymer Production by Paecilomyces japonica" Journal of microbiology and biotechnology, 10(4): 482~487
- Shon, Yun-Hee ; Kim, So-Yeun ; Lee, Jae-Sung ; Nam, Kyung-Soo 2000. "Enhancement of Phase II and Antioxidant Enzymes in Mice by Soybeans Fermentation with Basidiomycetes" Journal of microbiology and biotechnology, 10(6): 851~857
- Shon, Yun-Hee ; Kim, So-Yeun ; Lee, Jae-Sung ; Kim, Jong-Kook ; Nam, Kyung-Soo 2001. "Antimutagenic Effect of Polysaccharides Extracted from Soybeans Fermented with Basidiomycetes on 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)" Journal of microbiology and biotechnology, 11(2): 346~349
- Shon, Yun-Hee ; Nam, Kyung-Soo 2001. "In Vitro Cancer Chemopreventive Activities of Polysaccharides from Soybeans Fermented with Phellinus igniarius or Agrocybe cylindracea" Journal of microbiology and biotechnology, 11(6): 1071~1076
- 2002. "Optimal Production and Characterization of Fibrinolytic Enzyme from Fomitella fraxinea Mycelia." 한국미생물·생명공학회지 = Korean journal of microbiology and biotechnology, 30(4): 325~331
- Bae, Jae-Sung ; Jang, Kwang-Ho ; Park, Sung-Guk ; Jo, Woo-Sik ; Rhee, Man-Hee ; Kwon, Oh-Deog ; Kim, Young-Hoan ; Kim, Eun-Young ; Park, Seung-Chun 2003. "Acute Oral Toxicity of Extract Derived from Fruiting Body of Phellinus gilvus in Rats" Journal of toxicology and public health : an official journal of the Korean Society of Toxicology, 19(3): 211~215
- 2004. "Optimal Conditions of Mycelial Growth and Exopolysaccharide Production in Submerged Culture of Phellinus baumii" 생명과학회지 = Journal of life science, 14(1): 51~56
- 2004. "A study on the Mycelial Growth of Morchella esculenta" 생명과학회지 = Journal of life science, 14(1): 126~130
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