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Natural product sciences v.4 no.2, 1998년, pp.58 - 61  

Aphrodisiac Evaluation in Sexually Naive Male Mice after Chronic Administration of Eurycoma longifolia Jack

Ang, Hooi Hoon   (School of Pharmaceutical Sciences, University of Science Malaysia  ); Sim, Meng-Kwoon   (Department of Pharmacology, Faculty of Medicine, National University of SingaporeUU0014180  );
  • 초록

    Eurycoma longifolia Jack was evaluated for aphrodisiac property on sexually naive male mice using the electrical copulation cage. Optimum condition was provided for this study and the male mice were treated with 500 mg/kg of either chloroform, methanol, water or n-butanol fractions from E. longifolia Jack. However, the mice in the yohimbine and control groups received 30 mg/kg and 3 ml/kg of yohimbine and normal saline respectively. The male mice were then conditioned to seek either an estrous female, sexually vigorous male or no mouse, a measurement of right, wrong or no choice respectively. Besides this, hesitation time which was the time spent before the sexually naive male mice crossed the electrical grid (maintained at 0.12 mA) was also determined. Results showed that E. longifolia Jack possesses aphrodisiac property on the sexually naive male mice as shown by the slow and transient reduction in hesitation time and also a similar manner in the increase in the % of sexually naive male mice scoring right choice throughout the investigation period. Hence, this further supports the folkuse of this plant as aphrodisiac.


  • 주제어

    Eurycoma longifolia Jack .   Simaroubaceace .   aphrodisiac .   electrical grid .   hesitation time .   preference of choice.  

 저자의 다른 논문

  • Sim, Meng-Kwoon (2)

    1. 1997 "Effects of Eurycoma longifolia Jack on Sexual Beahviour of Male Rats" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 20 (6): 656~659    
    2. 1998 "Eurycoma longifolia Increases Sexual Motivation in Sexually Naive Male Rats" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 21 (6): 779~781    

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