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Nutraceuticals and food v.7 no.3, 2002년, pp.282 - 286   피인용횟수: 1

Plasma Concentrations of Fe, Cu, Mn, and Cr of Maternal and Umbilical Cord Blood during Pregnancy

Lee, Jong-Im   (Department of Food and Nutrition, Chonnam National University, Home Ecology Research InstituteUU0001112  ); Lim, Hyeon-Sook   (Department of Food and Nutrition, Chonnam National University, Home Ecology Research InstituteUU0001112  ); Cho, Young-Sook   (Division of Food Science, Sunchon National UniversityUU0000840  );
  • 초록

    Anemia is prevalent among pregnant women in Korea, and Fe deficiency anemia is a major nutritional problem throughout the world. Because studies of Cu, Mn, and Cr levels excluding Fe are rare, we were interested in changes in the nutritional status of these trace minerals and their relationship to hematogenesis. Accordingly, we determined the changes in plasma Fe, Cu, Mn, and Cr concentrations of maternal and umbilical cord blood during pregnancy, and evaluated the relationships between them at different time points during pregnancy. A total of 81 women participated in the study: 26 subjects in the first trimester, 23 in the second, and 32 in the third trimester. Plasma Fe levels were lower significantly (p $\mu\textrm{g}$ /dL) in each trimester were 86.6 $\pm$ 13.8, 111.6 $\pm$ 27.9, and 114.0 $\pm$ 29.7, respectively; with significant increases (p $\pm$ 89.0, 234.0 $\pm$ 140.0, and 240.3 $\pm$ 166.0, respectively and tended to increase, though not significantly, as the pregnancies progressed. The plasma concentrations of Cr (pg/dL) in each trimester were 3.7 $\pm$ 2.0, 3.1 $\pm$ 1.0, and 2.4 $\pm$ 1.2, respectively; and was significantly lower (p $\pm$ 74.6 $\mu\textrm{g}$ /dL, Cu was 57.5 $\pm$ 10.9 $\mu\textrm{g}$ /dL, Mn was 482.4 $\pm$ 111.1 pg/dL, and Cr was 9.3 $\pm$ 2.8 pg/dL. Plasma concentrations of Fe, Cu, Mn, and Cr of cord blood were 300 %, 50 %, 200 %, and 370% as compared to those of maternal blood in the third trimester. These results suggest that an active transport mechanism for the transport of Fe, Mn, and Cr from mother to fetus may exist, whereas, for Cu, the placenta appears to have a blocking effect on the transport from mother to baby.


  • 주제어

    Cu .   Mn .   Cr .   cord blood.  

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  • 이 논문을 인용한 문헌 (1)

    1. Kim, Hye-Ra ; Lim, Hyeon-Sook 2008. "Iron Intake During Pregnancy on Serum Concentrations of Trace Minerals in Mothers and Neonates" 韓國營養學會誌 = The Korean journal of nutrition., 41(3): 242~253     

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