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韓國營養學會誌 = The Korean journal of nutrition. v.35 no.7, 2002년, pp.729 - 736   피인용횟수: 1

Xylan으로부터 단리한 Glucuronic Acid가 유산소 운동 후 흰쥐 백근의 항산화계에 미치는 영향
Effect of Glucuronic Acid Derivertives Isolated from Xylan on Antioxidative Defense System in Rat White Gastrocnemius after Aerobic Exercise

김관유   (안산공과대학 식품공학과UU0000907  ); 이순재   (대구가톨릭대학교 식품영양학과UU0000343  );
  • 초록

    The purpose of this study was to investigate the effects of glucuronic acid (isolated from xylan) on antioxidative defense system in rat after aerobic exercise. The glucuronic acid was isolated from xylan. Sprague-Dawley male rats weighing 150 $\pm$ 10 g were randomly assigned to one normal group and three exercise training groups. Exercise training groups were classified to T (glucuronic acid free diet), TU (250 mg glucuronic acid/kg bw) and 2TU (500 mg glucuronic acid/kg bw) according to the level of glucuronic acid supplementation before exercise training. The experimental rats in exercise training groups (T, TU and 2TU) were exercised on glucuronic acid supplementation or rats in normal group (N) were confined in cage for 4 weeks. And rats were sacrificed with an overdose of pentobarbital injection just after running. Body weight, food intakes and food efficiency ratio (FER) were lower in the exercise training group than in the normal group. White gastrocnemius xanthine oxidase (XOD) activity in the T group was 85% greater than that of the normal group, whereas in the TU and 2TU groups it did not differ from the normal group. White gastrocnemius superoxide dismutase (SOD) activity in T group, that was decreased by 22% compared with that of N group, but those of TU and 2TU groups were increased by 38% and 42%, respectively, compared with that of T group. White gastrocnemius glutathione peroxidase (GSHpx) activity in T group, that was decreased by 42% compared with that of N group, but those of TU and 2TU groups were increased by 67% and 68%, respectively, compared with that of T group. Glutathione S-transferase (GST) activity of white gastrocnemius in N group was not significantly different from that in the T and TU groups, but 2TU group were increased by 12%. Contents of thiobarbituric acid reactive substance (TBARS) in T group was increased by 54%, compared with that of normal group but those of TU group and 2TU group were lower 44% and 36% than that of T group. In conclusion, the effects of glucuronic acids in exercise training rats would appear to reduce peroxidation of tissue as an antioxidative defense mechanism.

  • 주제어

    glucuronic acid .   exercise .   antioxidative system .   white gastrocnemius.  

  • 참고문헌 (42)

    1. Physical activity, diet, and health: Independent and interactive effects , Wood PD , Med Sci Sports Exerc / v.26,pp.838-834,
    2. Free radical chemistry : relationship to exercise , Jenkins RR , Sports Med / v.5,pp.156-170,
    3. Effect of garlic intake on the antifatigue recovery during prolonged exercise , Baek YH , J Korean Soc Food Nutr / v.24,pp.970-977,
    4. Effects of isolated from xylan on Antioxidative defense system and muscle fatigue recovry after aerobic exercise , Choi HM;Lee SC;Ryu SP;Rhee IK;Joo GJ;Rhee SJ , Korean J Nutrition / v.34,pp.872-880,
    5. Modern nutrition in halth and disease , Goodhart RH;Shils ME , 6th leu and Felbriger philadelphia / v.,pp.1045,
    6. Vitamin E status and response to exercise training , Tiidus PM;Houston ME , Sports Med / v.20,pp.12-23,
    7. Lipofuscine pigment accumulation in the nervous system of aging mice , Samorajski T;Ordy JM;Rudy Reimer P , Anat Res / v.160,pp.555-574,
    8. 高脂肪飼科をしたラットにおける運動負荷の影響とグルクロノラクトンの效果 , 失橋實之(外 六人) , 疲勞と休養の科學 / v.6,pp.45-57,
    9. Exercise-induced oxidative stress , Alwssio HM , Med Sci Sports Exerc / v.25,pp.218-224,
    10. Exercise and oxidative stress: Role of the cellular antioxidant systems , Ji LL , Gerontology / v.37,pp.317-325,
    11. Involvvement of the superoxide anion radical in antioxidation of pyrogallol and a convenient assay for superoxide dismutase , Marklund S;Marklund G , Eur J Biochem / v.47,pp.467-469,
    12. Selenium lipid peroxidase in cerebrovascular disorders determined by a new colormetric method , Satoh K , Clinica Chemica Acta / v.90,pp.37-43,
    13. Antioxidant Activity of Ethanol - Extracts of Defatted Soybean, Sesame, and Perilla Flours in a Soybean Oil - Water Emulsion System , Kim EH;Kim DH , Korean J Food Sci Technol / v.13,pp.283-289,
    14. Free radicals and tissue damage produced by exercise , Davies KJ;Quintanilha AT;Brooks GA;Packer L , Biochem Biophys Res Communi / v.107,pp.1198-1205,
    15. 筋運動におけるグルクロノラクトンの效果 , 野村晋一;失橋實之 , 疲勞と休養の科學 / v.5,pp.63-75,
    16. Antioxidative effect of tea extracts from green tea, oolong tea and black tea , Yeo SG;Ahn CW;Lee YW;Lee TG;Park YH;Kim SB , J Korean Soc Food Nutr / v.24,pp.299-304,
    17. Antioxidant enzyme response to exercise and aging , Ji LL , Med Sci Sports Exerc / v.25,pp.225-231,
    18. The effects of cumiss supplimentation on the changes of blood antioxidant and endurance in athletes , Roh SK;Kim CH , J Korea Exerc Nutr / v.3,pp.75-83,
    19. Effect of exercise training of antioxidant system in brain regions in rat , Somani SM;Ravi R;Rybak LP , Pharm Biochem Behavi / v.50,pp.635-639,
    20. Characterization of alternative molecular forms of xanthine oxidase in the mouse , Duke EJ;Joyce P;Ryan JP , J Biochem / v.131,pp.187-190,
    21. ラットの因憊走と筋病勞に對するグルクロノラクトンの效果 , 野村晋一;失橋實之 , 疲勞と休養の科學 / v.5,pp.49-62,
    22. Reactive oxygen in skeletal muscle. Intracellular oxidant kinetics and fatigue in vitro , Reid MB;Haack KE;Frankchek KM;Valberg PA;Kobzik L;West MS , J Appl Physio / v.73,pp.1797-1804,
    23. Glutathione peroxidase; Activity in selenium deficiency rat liver , Lawrence RA;Bruk RF , Biochem Biophy Res Commun / v.71,pp.952-958,
    24. Dietary supplementation of vitamin E protects heart tissue exercise induced oxidant stress , Kumar CT;Reddy VK;Prasad M;Thyagaraju K;Reddanna P , Mol Cell Biochem / v.111,pp.109-115,
    25. Skeletal muscle oxidative capacity, antioxidant enzymes and exercise training , Laughlin MH;Simpson T;Sexton WL;Brown OR;Smith JK;Korthuis RJ , J Appl Physico / v.68,pp.2337-2343,
    26. The regulation of liver xanthine oxidase , Stripe F;Della Corte , J Bio Chem / v.244,pp.3855-3863,
    27. Protein measurement with the folin phenol reagent , Lowry OH;Rosenbrough NJ;Farr AL;Randalll RJ , J Biol Chem / v.193,pp.265-275,
    28. Endurance training reduces the susceptibility of mouse skeletal muscle to lipid peroxidation in vitro , Salminen A;Vihko V , Acta Physiologica Scandinavica / v.117,pp.109-113,
    29. Response of human endothelial cell antioxidant enzymes to hyperoxia , Jornot L;Junod AF , Am J Respir Cell Mol Biol / v.6,pp.107-115,
    30. Superoxide and singlet oxygen catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity , Bus JS;Aust SD;Gibson JE , Biophys Res Commun / v.58,pp.749-753,
    31. Depletion of hepatic glutathione by ethanol occurs independently of ethanol metabolism , Speisky H;Kera Y;Penttla KE;Israel Y;Lindros KO , Alcol Clin Exp Res / v.12,pp.224-232,
    32. Exercise and Oxidative stress , Shin MS;Kim WS;Kim YS;Kim SS , The Korean Journal of Exercise Nutrition / v.2,pp.1-23,
    33. Reactive oxygen species in living system: Source, biochemistry and role in human disease , Halliwell B , Am J Med / v.91,pp.14-22,
    34. Hepatic lipid peroxidation and antioxidant enzyme responses to long-term voluntary physical-activity and aging , Parkhouse WS;Willis PE;Zhang J , Age / v.18,pp.11-17,
    35. Effect of antioxidants on the volatiles of loasted seame seeds , Soliman MA;Elsawy AA;Fadel HM;Osman F , J Agric Food Chem / v.33,pp.523-527,
    36. Glutathione S-transferase: the first enzymatic steps in mercapturic acid formation , Habig WH;Pabst MJ;Jakoby WB , J Biol Chem / v.249,pp.7130-7139,
    37. Antioxidantive activities of allium species , Shigezo N;Naohiki Y;Yoshio Y , Nippon Shokunin Kogro Gakkaish / v.28,pp.291-298,
    38. Antioxidants, tissue damage and endurance in trained and untrained young male rats , Venditti P;S Di Meo , Arch Biochem Biopys / v.331,pp.63-68,
    39. Antioxidant nutrients atherosclerosis and coronary heart disease , Michael FO , Br J Heart / v.73,pp.28-32,
    40. The biology of oxygen radicals, the superoxide radical is an agent of oxygen toxicity: superoxide dismutase provied an important defense , Fridovich I , Science / v.201,pp.875-880,
    41. Adaptations of glutathione antioxidant system to endurance training are tissue and muscle fiber specific , Leewenburgh C;Hollander J;Leichtweis S;Griffiths M;Gore M;Gore M;Ji LL , Am J Physio / v.272,pp.363-369,
    42. Antioxidant enzyme activities and lipid peroxidation levels in exercised and hypertensive rat tissues , Hong H;Johnson P , Inter J Biochem Cell Bio / v.27,pp.923-931,
  • 이 논문을 인용한 문헌 (1)

    1. 2002. "Effects of Green Tea on Hepatic Antioxidative Defense System and Muscle Fatigue Recovery in Rat after Aerobic Exercise" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 31(6): 1058~1064     

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