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대한간호학회지= Journal of Korean academy of nursing v.33 no.2, 2003년, pp.170 - 178   피인용횟수: 2

비타민 C 보충이 제 2형 당뇨병 환자의 혈당 및 항산화상태에 미치는 효과
Effect of Vitamin C Supplementation on Blood Sugar and Antioxidative Status in Types II Diabetes Mellitus Patients

박형숙   (부산대학교 의과대학 간호학과UU0000613  ); 이윤미   (인제대학교 의과대학 간호학과UU0001067  );
  • 초록

    Purpose: This study was to determine the effect of oral vitamin C supplements on blood sugar and antioxidative status in Types II diabetes mellitus patients. Method: Data for the study were collected from June 24 to August 31, 2001. Participants(31) took 1g/day vitamin C for 4 weeks, after a 1 - week taking no Vitamin C, followed by Vitamin C 3g/day for 4 weeks. A baseline blood sample was obtained following a 12hour overnight fast and at the end of each 4week Vitamin C administration. Blood samples were taken for plasma vitamin C concentration, fasting blood sugar, HbA1c, superoxide scavenging activity and hydrogen peroxide scavenging activity. The data were analyzed by SPSS for repeated measures ANOVA. Result: Plasma vitamin C concentration was significantly increased over dose(F=3.316, p=.043). Fasting blood sugar and HbA1c was significantly decreased over dose(F=13.192, p=.000; F=11.995, p=.000). Superoxide scavenging activity and hydrogen peroxide scavenging activity was significantly increased over dose(F=486.138, p=.000; F=177.704, p= .000). Conclusion: The results suggest that megadose vitamin C supplementation may have a beneficial effect in diabetes mellitus patients on both glycemic control and antioxidant status. Thus dietary measures to increase plasma vitamin C may be an important health strategy for reducing the compliance of diabetic patients


  • 주제어

    제 2형 당뇨병 .   비타민 C .   혈당 .   항산화상태.  

  • 참고문헌 (30)

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  • 이 논문을 인용한 문헌 (2)

    1. Hwang, Mi-Ri ; Soh, Ju-Ryoun ; Lim, Hyeon-Sook 2009. "Effects of Folic Acid and Ascorbate Supplementation on Plasma Homocysteine and Oxidative Stress in Patients with Type 2 Diabetes Mellitus" 韓國營養學會誌 = The Korean journal of nutrition., 42(2): 107~118     
    2. Oh, Se In ; Kwak, Chung Shil ; Lee, Mee Sook 2016. "The Comparative Analysis of Health Risk Factor according to HbA1c Level of Elderly Women Dwelling in Jeonla Province - Blood Health Status, Food Habit and Nutrient Intake -" 한국식품영양학회지 = The Korean journal of food and nutrition, 29(3): 392~403     

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