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임신 랫드에 투여한 GnRH와 HCG가 태아에 미치는 영향
Effects of the Administration of GnRH and HCG on the Fetus in Pregnant Rats

남현욱   (경북대학교 수의과대학UU0000096  ); 김영홍   (경북대학교 수의과대학UU0000096  ); 이근우   (경북대학교 수의과대학UU0000096  ); 손창호   (전남대학교 수의과대학UU0001112  );
  • 초록

    The effect of GnRH and/or hCG on the implantation, pregnancy, and the concentration of plasma estradiol and progesterone were studied in pregnant rats. GnRH 50, or 100ug and/or hCG 50 or 100 IU were administered once on day 2 or 9 of gestation, respectively. Rats were autopsied on days 8 or 16. Administration of GnRH on day 2 did not induce the prevention of implantation and termination of pregnancy but was able to induce termination of pregnancy administering on day 9. Administration of hCG induced delayed implantation on day 2 and termination of pregnancy on day 2 and 9. Administration of GnRH concomitant with hCG had no effect on prevention of implantation on day 2 but induced termination of pregnancy with a very increased fetal resorption on day 2 and with a moderate increased fetal resorption on day 9. Administration of GnRH concomitant with hCG on day 2 induced more increased termination of pregnancy compared to injection of GnRH or HCG and opposite result was observed on day 9. Plasma estradiol and progesterone concentrations by administering GnRH and/or hCG had no effect on the termination of pregnancy the pregnant rats.


  • 주제어

    GnRH .   hCG .   estrogen .   progesterone .   implantation .   termination of pregnancy.  

  • 참고문헌 (41)

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  • 이 논문을 인용한 문헌 (1)

    1. Park, Chang-Ho ; Lee, Gee-Dong ; Kim, Jung-Ok ; Kim, Kil-Soo ; Lee, Won-Young ; Hong, Joo-Heon 2008. "Effect of Bulnesia sarmienti Water Extracts on Lipid Metabolism in Neonatally Streptozotocin- Induced Diabetic Rats." 생명과학회지 = Journal of life science, 18(7): 999~1004     

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