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Natural product sciences v.10 no.6, 2004년, pp.325 - 329   피인용횟수: 3

In vitro Inhibitory Activities of Essential Oils from Oenanthe javanica DC against Candida and Streptococcus species

Shin, Seung-Won    (Duksung Women's University, College of Pharmacy  );
  • 초록

    The composition of essential oil from O. javanica was analyzed by gas chromatography-mass spectrometry. Using the broth dilution method and disk diffusion test, anti-microbial activities of the oil fraction and its main components were evaluated against various antibiotic-susceptible and resistant strains of pathogenic microorganisms. As a result of GC-MS analysis, 57 compounds, including ${\alpha}-terpinolene$ (28.1%), dl-limonene (16.0%), ${\gamma}-terpinene$ (10.3%), ${\beta}-pinene$ (9.7%) and ${\alpha}-pinene$ (6.0%) were identified in the essential oil fraction. The essential oil fraction of O. javanica and its main components exhibited significant inhibitory activities, particularly against Candida albicans (antibiotic-susceptible strains) and Streptococcus pneumoniae (antibiotic- susceptible and resistant strains). The main components of the O. javanica oil fraction displayed different patterns of activity against the three tested Candida species as exemplified by the differential minimum inhibiting concentration (MIC) values. The disk diffusion test showed that the activities were dose dependent.


  • 주제어

    Oenanthe javanica .   essential oil .   antifungal .   Candida albicans .   Streptococcus pneumoniae.  

  • 참고문헌 (17)

    1. Benincasa, M., Scocchia, M., Poddaa, E., Skerlavajb, B., Dolzanic, L., and Gennaro, R, Antimicrobial activity of Bac7 fragments against drug-resistant clinical isolates. Peptides, article in press (2004) 
    2. Girmenia, C., Venditti, M., and Martino, P, Fluconazole in combination with flucytosine in the treatment of fluconazoleresistant Candida infections. Diagn. Micr. Infec. Dis. 46(3), 227-231 (2003) 
    3. Goldman, G.H., Silva-Ferreira, ME, Reis-Marques, E., Savoldi, M., Perlin, D., Park, S., Martinez, C.G., Goldman, M.H., and Colombo, A.L., Evaluation of fluconazole resistance mechanisms in Candida albicans clinical isolates from HIVinfected patients in Brazil. Diagn. Micr. Infec. Dis. 50, 25-32 (2004). 
    4. Hammer, K, Carson, C.E, and Riley, T.V, In vitro activities of ketoconazole, econazole, miconazole, and Melaleuca altemifolia (tea tree) oil against Malassezia species. Antimicrob. Agents Ch. 44, 467-469 (2000) 
    5. Koneman, E.W., Allen, S.D., Janda, W.M., Schreckenberger, EC., and Winn, W.C., Diagnostic Micrbiology, J.B., Lippincott Company, p. 437 (1992) 
    6. May, T., Dailloux, M., Amiel, C., Laurain C., Canton, P., and Faou, AL., Mycobacterial infections in AIDS patients; Lorraine, France. J. Eur. Acad. Dermatol. 4, 100-103 (1995) 
    7. Perieiro, M., Losada, A., and Torbio, J., Adherence of Candida albicans strains isolated from AIDS patients. Comparison with pathogenic yeasts isolated from patients without HIV infection. Brit. J. Dennatol. 137(1) 76-80 (1997) 
    8. Slevin, M.L., Lowes J.A, Bell, R., Catto-Smith, A.G., Ford, J.M., Malpas, J.S., and Lister; T.A, The role of transtracheal aspiration in the diagnosis of respiratory infection in neutropenic patients with acute Leukaemia. Leukemia Res. 5, 165-168 (1981) 
    9. Giordani, R, Trebaux, J., Masi, M., and Regli, P, Enhanced antifungal activity of ketoconazole by Euphorbia characias latex against Candida albicans. J. Ethnophannacol. 78, 1-5 (2001) 
    10. Shin S., Essential oil compounds from Agastache rugosa as antifungal agents against Trichophyton species. Arch. Pharm. Res. 27, 295-299 (2004) 
    11. Shin S., Anti-Aspergillus activities of plant essential oils and their combination effects with ketoconazole or amphotericin B. Arch. Pharm. Res. 26, 389-393 (2003) 
    12. Eggimann, P; Garbino, J; Pittet, D., Epidemiology of Candida species infections in critically ill non- immunosuppressed patients. lLLncet Infectious Diseases 3,685-702 (2003) 
    13. Rhee, H.J., Koh, M.S., and Choi, OJ., A Study on the Volatile Constituents of the Water Dropwort (Oenanthe javanica DC) according to extraction methods, parts and heating methods. Korean J. Soc. Food Sci. 11, 386-395 (1995) 
    14. Baron, E.J., Peterson, L.R, and Finegold, S.M., Diagnostic Microbiology, Mosby,St Louis, P. 350 (1994) 
    15. Shin, S., and Kang, CA, Antifungal activity of the essential oil of Agastache rugosa Kuntze and its synergism with ketoconazole. Lett. Appl. Microbiol. 36, 111-115 (2003) 
    16. Shahidi-Bonjar, G.H., Inhibition of Clotrimazole-resistant Candida albican.I' by plants used in Iranian folkloric medicine. Fitoterapia 75(1), 74-76 (2004) 
    17. Teale, C.J., Antimicrobial resistance and the food chain. J. of Appl. Microbiol. 92(1), 85-89 (2002) 
  • 이 논문을 인용한 문헌 (3)

    1. Shin, Seung-Won 2005. "In Vitro Inhibitory Activities of Essential Oils from the Aerial Parts of Glehnia littoralis and its Main Components Against Antibiotic-Susceptible and -Resistant Strains of Streptococcus pneumoniae" 약학회지 = Yakhak hoeji, 49(4): 312~316     
    2. 2005. "" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, 28(7): 765~769     
    3. 2008. "" Natural product sciences, 14(2): 138~142     

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