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한국산 겨우살이(Viscum album var. coloratum)로부터 분리한 homo-flavoyadorinin-B의 항산화 활성
An Antioxidant Homo-Flavoyadorinin-B from Korean Mistletoe (Viscum album var. coloratum)

최승영   (경북대학교 응용생물화학부UU0000096  ); 정신교   (경북대학교 식품공학과UU0000096  ); 김숙경   (경북대학교 식품공학과UU0000096  ); 유영춘   (건양대학교 의과대학UU0000053  ); 이경복   (건양대학교 의과대학UU0000053  ); 김종배   (한동대학교 생명 식품공학부UU0001484  ); 김자영   (경북대학교 응용생물화학부UU0000096  ); 송경식   (경북대학교 응용생물화학부UU0000096  );
  • 초록

    An antioxidant was isolated from Korean mistletoe (Viscum album var. coloratum) by consecutive purification using silica gel, Sephadex LH-20, and RP-HPLC. The active principle was identified as homo-flavoyadorinin-B (3',7-dimethoxyluteolin-4'-O-[apiosyl $(1{\rightarrow}2)$ glucoside]) by spectral analyses. It inhibited 74.6% of hydroxyl radical and 30.6% of superoxide anion radical at 0.01 mM; however, th~compound did not show any scavenging activity against hydrogen peroxide radical. At 0.1 mM, above compound scavenged superoxide anion radical about twice as effective as positive controls, BHT and ${\alpha}-tocopherol$ . Radical scavenging activities of homo-flavoyadorinin-B on DPPH, hydroxyl, and hydrogen peroxide radicals were almost same with those of positive controls.

  • 주제어

    Viscum album var.   coloratum .   reactive oxygen species scavenger .   antioxidant .   homo-flavoyadorinin-B.  

  • 참고문헌 (21)

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  • 이 논문을 인용한 문헌 (6)

    1. Kim, Han-Soo 2006. "Effects of the Korean Mistletoe Hot-Water Extract on the Lipid Components and Blood Pressure Level in Spontaneously Hypertensive Rats" 생약학회지, 37(3): 169~176     
    2. Shin, In-Cheol ; Sa, Jae-Hoon ; Shim, Tae-Heum ; Lee, Jin-Ha 2006. "The Physical and Chemical Properties and Cytotoxic Effects of Acer tegmentosum Maxim. Extracts" 한국응용생명화학회지 = Journal of the Korean Society for Applied Biological Chemistry, 49(4): 322~327     
    3. Jeong, Hyun-Jin ; Park, Seon-Bin ; Kim, Sun-A ; Kim, Hyun-Ku 2007. "Total Polyphenol Content and Antioxidative Activity of Wild Grape (Vitis coignetiae) Extracts Depending on Ethanol Concentrations" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 36(12): 1491~1496     
    4. Lee, Jung-Lim ; Ahn, Jae-Hyung ; Hwang, Seong-Gu ; Jung, Yeon-Hwa ; Yang, Hyo-Seon ; Kang, Tae-Bong ; Kim, Jong-Bae ; Yoo, Yung-Choon 2010. "The Immunoadjuvant Activity of The Water-Extract of Korean mistletoe (Viscum album var. coloratum) Fruit" 생약학회지, 41(4): 275~281     
    5. Lee, Jung-Lim ; Jeon, Young-Ha ; Yang, Hyo-Seon ; Lee, Kyung-Bok ; Song, Kyung-Sik ; Kang, Tae-Bong ; Kim, Jong-Bae ; Yoo, Yung-Choon 2010. "The Immunostimulatory Activity of The Water-Extract of Korean Mistletoe Fruit to Activate Murine Peritoneal Macrophages" 생약학회지, 41(2): 122~129     
    6. Kim, Chul-Woo ; Yi, Jae-Seon 2013. "Germination and Seedling Induction of Viscum album var. coloratum (Kom.) Ohwi after Artificial Inoculation on the Branch of Host Plants" Journal of forest science, 29(2): 173~180     

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