본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

식품산업과 영양 = Food industry and nutrition v.9 no.1, 2004년, pp.36 - 45   피인용횟수: 1

Biological Activity of Bamboo Salt

Shin, Hye-Young   (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, College of Pharmacy Wonkwang UniversityUU0001021  ); Na, Ho-Jeong   (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, College of Pharmacy Wonkwang UniversitUU0001575  ); Moon, Phil-Dong   (Department of Pharmacology, College of Oriental Medicine, Kyung Hee University, College of Pharmacy Wonkwang UniversitUU0001575  ); Seo, Sang-Wan   (College of Pharmacy Wonkwang Universit  ); Shin, Tae-Yong   (College of Pharmacy, Woosuk Universit  ); Hong, Seoung-Heon   (College of Pharmacy Wonkwang Universit  ); Lee, Ki-Nam   (Professional Graduate School, Wonkwang Universit  ); Park, Rae-Kil   (VCRC of Wonkwang Universit  ); Kim, Hyung-Min   (Department of Pharmacology, College of Oriental Medicine, Kyung Hee UniversityUU0001575  );
  • 초록

    Bamboo salt has been used for the purpose of prevention and treatment of various diseases in Korea. Present study was carried out to ascertain the effects of purple bamboo salt upon anti-allergic effect, anti-inflammatory activity and immune-enhance effect as well. Purple bamboo salt significantly inhibited the ear swelling response and histamine release induced by compound 48/80 in mice and rat peritoneal mast cells. Purple bamboo salt (0.01 ∼ lg/kg) also dose-dependently inhibited the passive cutaneous anaphylaxis by oral administration. Purple bamboo salt (1 mg/mL) in hibited phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor (TNF)- ${\alpha}$ , interleukin (IL)-1 ${\beta}$ and IL-6 secretion, by 67.04 ${\pm}$ 0.08%, 68.01 ${\pm}$ 1.85%, 69.48 ${\pm}$ 0.54%, respectively. In addition, purple bamboo salt inhibited the expression of TNF- ${\alpha}$ mRNA in HMC-1 cells. Finally, we investigated the effect of purple bamboo salt in the forced swimming test (FST) and the change of purple bamboo salt-mediated cytokine production from MOLT-4 cells. At the 7th, immobility time was significantly decreased in the purple bamboo salt-administration group (35.4 ${\pm}$ 5.9 s for 1 g/kg) in comparison with the control group (93.2 ${\pm}$ 15.45). After FST, the content of glucose in the blood serum was increased and the levels of blood urea nitrogen, lactic dehydrogenase was decreased in purple bamboo salt-administration group. However, it had no effect on the elevation of CK and TP level. Purple bamboo salt (1 mg/mL) significantly increased the interferon (IFN)- ${\gamma}$ and IL-2 level compared with media control (about 3.7-fold for IFN- ${\gamma}$ , about 3.5-fold for IL-2, p〈0.05) but did not affect the IL-4.


  • 주제어

    purple bamboo salt .   immediate-type allergic reactions .   anti-inflammatory activity .   immune-enhance effect.  

  • 참고문헌 (46)

    1. A study on the effects of cetylpyridinim chloride and bamboo salt containing mouth rinse on the number of streptococcus mutans and plaque index , Kim JB;Paik DI;Moon HS;Jin BH;Park DY , J Kor Acad Dent Health / v.17,pp.176-186,
    2. The reducing effects on dental plaque formation and gingiritis of toothpastes containing bamboo salt and several herb medicines , Min BS;Choi HY;Choi YJ;Hong JP;Chun YH;Kang NH , J Kor Dent Ass / v.33,pp.65-71,
    3. Pharmacological evaluation of bamboo salt , Yang JS;Kim OH;Chung SY;Yoo TM;Roh YN;Yi SY;Chung MW;Ahn MR;Choi HJ;Rheu HM , J Appl Pharm / v.7,pp.178-184,
    4. Protective effect of an aged garlic-bamboo salt mixture on the rat with the alcohol-salicylate induced gastropathy , Huh K;Kim YH;Jin DQ , Yakhak Hoeji / v.45,pp.258-268,
    5. Wasserman SI;Marquardt DL , Anaphylaxis in allergy:Principles and Practice(3rd ed.) / v.,pp.1365,
    6. Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea , Hua XY;Back SM;Tam EK , America Journal of Physiology / v.270,pp.L985-991,
    7. Suppression of L-histidine decarboxylase mRNA expression by methyleugenol , Shin BK;Lee EH;Kim HM , Biochemical and Biophysical Research Communications / v.232,pp.188-191,
    8. Extracellular ATP activates mast cells via a mechanism that is different from the activation induced by the cross-linking of Fc receptors , Sudo N;Tanaka K;Koga Y;Okumura Y;Kubo C;Nomoto K , Journal of Immunology / v.156,pp.3970-3979,
    9. Mast cells:function, differentiation and activation , Pearce FL , Current Opinion in Immunology / v.1,pp.630-636,
    10. Shini-san inhibits mast cell-dependent immediate-type allergic reactions , Kim HM;Lee YH;Chae HJ;Kim HR;Baek SH;Lim KS;Hwang CY , American J of Chinese Medicine / v.27,pp.377-386,
    11. Tongkyutang inhibits mast cell-dependent allergic reactions and inflammatory cytokines secretion , Na HJ;Jeong HJ;Bae H;Kim YB;Park ST;Yun YG;Kim HM , Clinica Chimica Acta / v.319,pp.35-41,
    12. Ixeris dentata green sap inhibits both compound 48/80-induced anaphylaxis-like response and IgE-mediated anaphylactic response in murine model , Yi JM;Hong SH;Lee HJ;Won JH;Kim JM;Jeong DM;Baek SH;Lim JP;Kim HM , Biological and Pharmaceutical Bulletin / v.25,pp.5-9,
    13. Allergen-induced histamine release in intact human skin in vivo assessed by skin microdialysis technique:Characterization of factors influencing histamine releasability , Petersen LJ;Mosbech H;Skov P , J Allergy Clin Immunol / v.97,pp.672-679,
    14. Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation , Segal DM;Taurog J;Metzger H , Proc Natl Acad Sci USA / v.74,pp.2993-2997,
    15. The receptor with high affinity for immunoglobulin E , Metzger H;Alcaraz G;Hohman R;Kinet JP;Pribluda V;Quarto R , Annu Rev Immunol / v.4,pp.419-470,
    16. Structure/function relationships in the mast cell high-affinity receptor for IgE(Fc ${\varepsilon}$ RI):Role of cytoplasmic domains , Alber G;Miller L;Jelsema C;Varin-Bland N;Metzger H , J Biol Chem / v.266,pp.22613-22620,
    17. A new method for extraction of extravasated dye in the skin and the influence of fastine stress on passive cutaneous allergy in guinea pigs and rats , Katayama S;Shionoya H;Ohtake S , Microbiol Immunol / v.22,pp.89-101,
    18. $^{125}I$-fibrin deposition in IgE dependent immediate hypersensitivity reaction in mouse skin. Demonstration of the role of mast cells using mast cell-deficient mice locally reconstituted with cultured mast cells , Wershil BK;Merkori YA;Murakame T;Galli SJ , J Immunol / v.139,pp.2605-2614,
    19. New concepts about the mast cell , Galli SJ , N Engl J Med / v.328,pp.257-265,
    20. Behavioral despair in mice:a primary screening test for antidepressants , Porsolt RD;Bertin A;Jalfre M , Arch Int Pharmacodyn Ther / v.229,pp.327-336,
    21. Evidence that imipramine activates 5-HT1C receptor function , Borsini F;Cesana R;Vidi A;Mennini T , Eur J Pharmacol / v.203,pp.359-363,
    22. Effect of chronic treatment with the antidepressant tianeptine on the hypothalamo-pituitary-adrenal axis , Delbende C;Tranchand Bunel D;Tarozzo G;Grino M;Oliver C;Mocaer E;Vaudry H , Eur J Pharmacol / v.251,pp.245-251,
    23. Forced swim test-induced endocrine and immune changes in the rat:effect of subacute desipramine treatment , Connor TJ;Kelly JP;Leonard BE , Pharmacol Biochem Behav / v.59,pp.171-177,
    24. Multifactorial method for assessing the physical work capacity of mice , Dubovik BV;Bogomazov SD , Farmakol Tosikol / v.50,pp.116-121,
    25. Pharmacological study on Agkistrodon blomhoffii blomhoffii BOIE. V. anti-fatigue effect of the 50% ethanol extract in acute weight-loaded forced swimming-treated rats , Moriura T;Matsuda H;Kubo M , Biol Pharm Bull / v.19,pp.62-66,
    26. Constituents and pharmacological effects of Eucommia and Siberian ginseng , Deyama T;Nishibe S;Nakazawa Y , Acta Pharmacol Sinica / v.12,pp.1057-1070,
    27. Anti-stress and anti-fatigue effect of fermented rice bran , Kim KM;Yu KW;Kang DH;Suh HJ , Phytother Res / v.16,pp.700-702,
    28. Exogenous glutathione increases endurance to muscle effort in mice , Novelli GP;Falsini S;Bracciotti G , Pharmacol Res / v.2,pp.149-155,
    29. Effects of Gentiana lutea ssp. symphyandra on the central nervous system in mice , Ozturk N;Husnu Can Baser K;Aydin S;Ozturk Y;Calis I , Phytother Res / v.7,pp.627-631,
    30. Serum biochemical values in sled dogs before and after competing in long-distance races , Burr JR;Reinhart GA;Swenson RA;Swaim SE;Vaughn DM;Bradley DM , J Am Vet Med Assoc / v.211,pp.175-179,
    31. Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolohged exercise , Coombes JS;McNaughton LR , J Sports Med Phys Fitness / v.40,pp.240-246,
    32. Sports and type I diabetes:personal experience , Dorchy H , Rev Med Brux / v.23,pp.A211-217,
    33. TH1 and TH2 cells:different patterns of lymphokine secretion lead to different functional properties , Mosmann TR;Coffman RL , Annu Rev Immunol / v.7,pp.145-173,
    34. T cell effector subsets:extending the Th1/Th2 paradigm , Chtanova T;Mackay CR , Adv Immunol / v.78,pp.233-266,
    35. Interleukin-12-secreting fibroblasts are more efficient than free recombinant interleukin-12 in inducing the persistent resistance to Mycobacterium avium complex infection , Kang BY;Chung SW;Lim YS;Kim EJ;Kim SH;Hwang SY;Kim TS , Immunology / v.97,pp.474-480,
    36. Adjuvants and the promotion of Th1-type cytokines in tumor immunotherapy , Dredge K;Marriott JB;Todryk SM;Dalgleish AG , Cancer Immunol Immunother / v.51,pp.521-531,
    37. T-helper type 2 cell-directed therapy for asthma , Cohn L;Ray A , Pharmacol Ther / v.88,pp.187-196,
    38. Functional diversity of helper T lymphocytes , Abbas AK;Murphy KM;Sher A , Nature / v.383,pp.787-793,
    39. Supernormal histamine release and normal cytotoxic activity of Beige rat mast cells with giant granules , Jippo Kanemoto T;Kasugai T;Yamatodani A;Ushio H;Mochizuki T;Tohya K;Kimura M;Nishimura M;Kitamura Y , International Archives Allergy and Immunology / v.100,pp.99-106,
    40. Native heparin from rat peritoneal mast cells , Yurt RW;Leid RW;Austen KF , J of Biological Chemistry / v.252,pp.518-521,
    41. A new method for extraction of extravasated dye in the skin and the influence of fastine stress on passive cutaneous allergy in guinea pigs and rats , Katayama S;Shionoya H;Ohtake S , Microbiol Immunol / v.22,pp.89-101,
    42. Inflammatory and atherosclerotic interactions in the depleted uremic patients , Stenvinkel P , Blood Purif / v.19,pp.53-61,
    43. Intracellular calcium release induced by histamine releasers and its inhibition by some antiallergic drugs , Tasaka K;Mio M;Okamoto M , Ann Allergy / v.56,pp.464-469,
    44. Cancer vaccines , Dalgleish AG , Br J Cancer / v.82,pp.1619-1624,
    45. Regulatory effect of cytokine production in asthma patients by SOOJICHIM (Koryo Hand Acupuncture Therapy) , Jeong HJ;Kim BS;Kim KS;Kim HM , Immunopharmaol Immunotoxicol / v.24,pp.265-274,
    46. Reduced IL-2 but elevated IL-4, IL-6 and IgE serum levels in patients with cerebral infarction during the acute stage , Kim HM;Shin HY;Jeong HJ(et al.) , J Mol Neurosci / v.14,pp.191-196,
  • 이 논문을 인용한 문헌 (1)

    1. 2009. "" Journal of the Korean Society for Applied Biological Chemistry, 52(3): 264~269     

 저자의 다른 논문

  • Shin, Hye-Young (8)

    1. 2003 "Anti-allergic Effect of Aqueous Extract of Stachys riederi var.japonica Miq.in vivo and in vitro" Natural product sciences 9 (1): 44~48    
    2. 2003 "Effect of Bamboo salt-pro on carries-inducing properties of Streptococcus mutans" Oriental pharmacy and experimental medicine 3 (1): 40~45    
    3. 2003 "Immune-enhancement effect of JaSaengHwan" Oriental pharmacy and experimental medicine 3 (1): 34~39    
    4. 2003 "Effect of Terminalia chebula fruit on anaphylaxis by anal therapy" Oriental pharmacy and experimental medicine 3 (2): 56~62    
    5. 2004 "Anti-allergic Effects of Artemisia iwayomogi on Animal Models of Allergic Reactions" Natural product sciences 10 (1): 24~28    
    6. 2007 "Immunostimulatory effect of Korean traditional medicine Acanthopanacis Cortex" Natural product sciences 13 (4): 283~288    
    7. 2007 "The Anti-allergic Effect of Vinegar Treated Small Black Soybean (Glycine max Merr.) is Mediated Through Inhibition of Histamine Release and Inflammatory Cytokine Secretion" Natural product sciences 13 (4): 337~341    
    8. 2007 "시라자 추출물을 함유하는 면역질환의 치료 및 예방을 위한 면역증강용 조성물" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine 21 (3): 700~704    
  • Moon, Phil-Dong (6)

  • Kim, Hyung-Min (32)

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • NDSL :
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 이용한 콘텐츠
이 논문과 함께 출판된 논문 + 더보기