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게르마늄 및 게르마늄 분말 용해수로 재배한 콩나물의 위암세포 성장억제 작용
The Growth Inhibition against Gastric Cancer Cell in Germanium or Soybean Sprouts Cultured with Germanium

김은정   (부산대학교 식품영양학과 및 김치연구소UU0000613  ); 이경임   (양산대학 호텔조리과UU0000924  ); 박건영   (부산대학교 식품영양학과 및 김치연구소UU0000613  );
  • 초록

    The growth inhibitory effect of germanium, or soybean sprouts cultured with germanium, on cancer cells was determined in the cultured gastric cancer cell line, AGS. The growth of AGS was significantly inhibited by the addition of 0.01-1% organic germanium (Ge-132) and germanium stone powder in MTT cytotoxicity assays. The juice from germanium treated soybean sprouts (GTS) inhibited the growth of AGS gastric cancer cells by 78-88% at concentrations of 2.5 or 5 ${\mu}\ell$ . The juice from Seomoktae GTS revealed an especially higher growth inhibitory effect than that from the control soybean sprouts (germanium non-treated soybean sprouts, GNTS) in AGS. The results suggest that soybean sprouts cultured with germanium may exert an anticancer effect against gastric cancer cells.


  • 주제어

    germanium .   soybean sprouts .   gastric cancer cell .   anticancer effect.  

  • 참고문헌 (19)

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  • 이 논문을 인용한 문헌 (7)

    1. 2007. "" Journal of food science and nutrition, 12(1): 16~22     
    2. Jeong, Oh-Hyun ; Kim, Ahn-Keun ; Yang, Ki-Sook ; Pyo, Myoung-Yun 2008. "Effects of Carboxylethylgermanium Sesquioxide on the Cyclophosphamide-induced Immunotoxicity in Mice" 환경독성학회지 = Journal of environmental toxicology, 23(4): 301~306     
    3. Lee, Soo-Jin ; Lee, Kyeoung-Im ; Moon, Suk-Hee ; Park, Kun-Young 2008. "Antimutagenic Effects on Methanol Extracts of Doenjang Made with Various Kinds of Water or Salt" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 37(6): 691~695     
    4. Han, Eun-Ju ; Kim, Joong-Man 2011. "Quality Characteristics of Yanggaeng Prepared with Different Amounts of Ginger Powder" 東아시아食生活學會誌 = Journal of the East Asian Society of Dietary Life, 21(3): 360~366     
    5. Sung, Hea Mi ; Kim, Sook Jeong ; Kim, Kyoung Mi ; Yun, Su Kyoung ; Jung, Hyun Jung ; Kim, Tae Yong ; Wee, Ji Hyang 2014. "Antioxidant Activity of Soy-sprout Extracts Prepared by Enzyme and Ultra High Pressure" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 43(8): 1228~1235     
    6. Kim, Kyoung Mi ; Jung, Hyun Jung ; Sung, Hea Mi ; Wee, Ji-Hyang ; Kim, Tae Yong ; Kim, Ki Myong 2014. "Study of the Antioxidant and Alcohol-degrading Enzyme Activities of Soybean Sprout Sugar Solutions" 한국식품과학회지 = Korean journal of food science and technology, 46(5): 581~587     
    7. Sung, Hea Mi ; Jung, Hyun Jung ; Yun, Su Kyoung ; Kim, Tae Yong ; Kim, Ki Myong ; Wee, Ji-Hyang 2014. "Effect of a Soy-Sprout Beverage Prepared with High-Concentrated Oxygen Water on Alcohol Metabolism in Rats" 한국식품과학회지 = Korean journal of food science and technology, 46(5): 616~621     

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