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Effect of Phenanthrene on Gill Biotransformation in Olive Flounder (Paralichthys olivaceus)

Jee Jung-Hoon    (Institute of Fisheries Sciences, Pukyong National University   ); Kang Ju-Chan    (Department of Aquatic Life Medicine, Pukyong National University  );
  • 초록

    The potential of phenanthrene to induce xenobiotic responses was investigated. Olive flounder (Paralichthys olivaceus) was exposed to different levels of phenanthrene $(0.5,\;1\;and\;{\mu}M)$ for 4 weeks, Gill CYP450 content and EROD (ethoxyresorufin O-deethylation) activity were found to be significant in the flounders treated with the higher concentration of phenanthrene $(>1.0\;{\mu}M)$ , however, there were no significant changes in gill PROD (penthoxyresorufin O-deethylation) activity in all treated group compared to the controls. This study demonstrated that phenanthrene has potential to induce gill cytochrome P450 and EROD enzyme in olive flounder.


  • 주제어

    CYP450 .   EROD .   Gill .   Paralichthys olivaceus .   Phenanthrene.  

  • 참고문헌 (34)

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