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Biotechnology and bioprocess engineering v.9 no.6, 2004년, pp.447 - 453   피인용횟수: 3

Effects of Modifiers on the Supercritical $CO_{2}$ Extraction of Glycyrrhizin from Licorice and the Morphology of Licorice Tissue after Extraction

Kim Hyun Seok    (Department of Chemical and Biochemical Engineering, University of Suwon   ); Lee Sang Yun    (Department of Chemical and Biochemical Engineering, University of Suwon   ); Kim Byung Yong    (Department of Food Science and Technology, Kyunghee University   ); Lee Eun Kyu    (Department of Chemical Engineering, Hanyang University   ); Ryu Jong Hoon    (Department of Chemical and Biochemical Engineering, University of Suwon   ); Lim Gio Bin    (Department of Chemical and Biochemical Engineering, University of Suwon  );
  • 초록

    Optimal conditions for the supercritical carbon dioxide $(scCO_{2})$ extraction of glycyr­rhizin from licorice (Glycyrrhiza glabra) were investigated, with an emphasis on the types and levels of modifiers. The morphology of the licorice tissue remaining after the $scCO_{2} $ extraction of glycyrrhizin was examined by scanning electron microscopy, coupled with measurements of ab­solute density. Conventional organic solvent extraction was also carried out for purpose of quantitative comparison. At 50 MPa and $60^{circ}C$ glycyrrhizin could not be extracted with pure $scCO_{2}$ , while a considerable amount of glycyrrhizin was extracted when water was added to $scCO_{2}$ as a modifier. The highest recovery was found to be about $97\%$ when $70\%$ aqueous methanol was added to $scCO_{2}$ at a concentration of $15\%$ . The optimal pressure and temperature for the supercritical fluid extraction of glycyrrhizin were observed to be 30 M Pa and $60^{circ}C$ , respectively. Under these conditions, the percentage recovery of glycyrrhizin attained a maximum value of 102.67\pm$ $1.13\%$ within 60 min. Furthermore, in the case of $scCO_{2}$ modified with $70\%$ aqueous methanol, the licorice tissue obtained after extraction was found to be severely de­graded by excessive swelling, and the absolute density of the licorice residues was observed to be the highest.


  • 주제어

    supercritical carbon dioxide .   extraction .   licorice .   glycyrrhizin.  

  • 참고문헌 (24)

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  • 이 논문을 인용한 문헌 (3)

    1. 2008. "" Biotechnology and bioprocess engineering, 13(6): 671~676     
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    3. Do, Jin-Sun ; Song, Shin-Young ; Cho, Ki-Jung ; Kim, In-Ho 2011. "Separation of Egg White Using HPLC with Change of Mobile Phase and Temperature" Korean chemical engineering research = 화학공학, 49(6): 829~834     

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