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Journal of ginseng research = 高麗人參學會誌 v.28 no.4 = no.76, 2004년, pp.173 - 182   피인용횟수: 4

Korean Red Ginseng Significantly Slows CD4 T Cell Depletion over 10 Years in HIV-1 Infected Patients: Association with HLA

Cho, Young-Keol    (Department of Microbiology, University of Ulsan College of Medicine   ); Sung, Heungsup    (Department of Microbiology, University of Ulsan College of Medicine   ); Kim, Tai Kyu    (Department of Microbiology, College of Medicine, The Catholic University of Korea   ); Lim, Ji Youn    (Department of Microbiology, University of Ulsan College of Medicine   ); Jung, You Sun    (Department of Microbiology, University of Ulsan College of Medicine   ); Kang, Sang-Moo    (Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine  );
  • 초록

    We have shown that long-term intake of Korean red ginseng (KRG) delays disease progression in HIV-I infected patients. In the present study to investigate whether this slow progression was associated with protective human leukocyte antigen (HLA) alleles as well as with KRG-intake, we have performed clinical analysis of 31 HIV-1 infected patients who have been living for more than 10 years without any antiretroviral therapy. Average amount of KRG-intake over $130\;{\pm}16$ months was $4,797\;{\pm}4,921\;g$ and the annual decrease in CD4 T cell (AD) was $30\;{\pm}29{\mu}L$ . We observed significant correlations among amount of KRG-intake, AD(r=-0.53, P $AD(14/{\mu}L)$ in the 16 patients who had taken higher amounts of KRG was significantly less than that $(49/{\mu}L)$ in the 15 patients with a little or no KRG-intake (P


  • 주제어

    Korean red ginseng .   HLA .   HIV-1 RNA .   CD4 T cells .   Correlation.  

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  • 이 논문을 인용한 문헌 (4)

    1. 2010. "" Journal of applied biological chemistry, 53(4): 202~206     
    2. 2010. "" Journal of ginseng research = 高麗人參學會誌, 34(3): 219~226     
    3. 2011. "" Journal of ginseng research = 高麗人參學會誌, 35(4): 413~420     
    4. 2016. "" Journal of ginseng research = 高麗人參學會誌, 40(4): 309~314     

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