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Natural product sciences v.11 no.2, 2005년, pp.97 - 102   피인용횟수: 6

The Chemical Constituents and their Antioxidant Activity of the Stem of Rhododendron mucronulatum

Lee, Jin-Hoon    (College of Pharmacy, Kangwon National University   ); Jeon, Wan-Joo    (Department of Pharmacology, College of Medicine, Kangwon National University   ); Yoo, Eun-Sook    (Department of Pharmacology, College of Medicine, Cheju National University   ); Kim, Chang-Min    (College of Pharmacy, Kangwon National University   ); Kwon, Yong-Soo    (College of Pharmacy, Kangwon National University  );
  • 초록

    From the n-BuOH soluble traction of the 70% aqueous acetone extract of Rhododendron mucronulatum stem, twelve compounds were isolated. On the basis of spectral data, they were identified as scopoletin (1), (+)-taxifolin (2), quercetin (3), (-)-catechin (4), (+)-epicatechin (5), scopolin (6), lyoniside (7), ssioriside (8), fraxin (9), $(+)-lyoniresinol-3{\alpha}-O-{\beta}-D-glucopyranoside$ (10), $(+)-taxifolin-3-O-{\alpha}-L-arabinopyranoside$ (11), and astragalin (12), respectively. All isolated compounds were tested antioxidant activity against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical. Compounds 2 and 3 showed the potent antioxidant activity, and compounds 5, 8, and 11 showed moderate activity.


  • 주제어

    Rhododendron mucronulatum .   Ericaceae .   flavonoids .   lignans .   coumarins .   antioxidant activity.  

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  • 이 논문을 인용한 문헌 (6)

    1. Kim, Gi-Beom ; Shin, Kwan-Seog ; Kim, Chang-Min ; Kwon, Yong-Soo 2006. "Flavonoids from the Leaves of Rhododendron schlipenbachii" 생약학회지, 37(3): 177~183     
    2. Hong, He-Sun ; Jeon, Seung-Ho ; Kwon, Yong-Soo 2007. "Cytotoxic constituents from the stem of Rhododendron mucronulatum" 생약학회지, 38(3): 227~233     
    3. Kim, Seong-Jin ; Lee, Jeong-Joo ; Lee, Sa-Im ; Park, Hee-Wook ; Lee, Jae-Hyeok ; Park, Jeong-Suk ; Kim, Sung-Hoon ; Baek, Nam-In ; Kwon, Young-Ee ; Yang, Jae-Heon ; Chae, Byeong-Suk ; Lim, Jong-Pil ; Shin, Tae-Yong ; Jeon, Hoon ; Eun, Jae-Soon ; Kim, Dae-Keun 2007. "Lignan Glycosides of Vaccinium oldhami Miquel" 생약학회지, 38(3): 296~298     
    4. 2009. "" Journal of the Korean Society for Applied Biological Chemistry, 52(5): 493~497     
    5. 2011. "" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, 34(9): 1459~1466     
    6. Kim, Jong Yeob ; Kim, Chang Su ; You, Dong Hyun ; Kim, Dong Won ; Choi, Dong Chil ; Kim, Jeong Man ; Oh, Nam Ki ; Park, Chun Geun ; Ahn, Young Sup ; Lee, Kang Soo 2014. "Cuttings for Mass Propagation Affecting the Impact of Increasing Reproductive Efficiency of Schisandra chinensis" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 22(3): 231~236     

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