본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Food science and biotechnology v.14 no.1 = no.61, 2005년, pp.123 - 130   피인용횟수: 22

Antioxidant Activities of Garlic (Allum sativum L.) with Growing Districts

Lee, Eun-Jung   (Department of Food and Nutrition, Hannam UniversityUU0001481  ); Kim, Kwan-Soo   (Department of Food and Nutrition, Hannam UniversityUU0001481  ); Jung, Hye-Young   (R & D Center for Future Technologies, Altwell Inc.  ); Kim, Deuk-Ha   (R & D Center for Future Technologies, Altwell Inc.  ); Jang, Hae-Dong   (Department of Food and Nutrition, Hannam UniversityUU0001481  );
  • 초록

    Hydrogen-donating capacity, scavenging activity of reactive oxygen including superoxide anion radical and hydrogen peroxide, metal-chelating activity, and reducing power of garlic extracts were investigated. All tested garlic extracts exhibited in vitro antioxidant activities, with Uiseong extract showing highest hydrogen-donating and hydrogen peroxide-scavenging activities, and reducing power, followed by Seosan and Samchek extracts, in proportion to total thiosulfinate contents. Higher scavenging activity of superoxide anion radical was observed in Uiseong than Seosan and Samchek extracts. Metal-chelating activity increased in order of Uiseong $Cu^{+2}$ -induced human LDL oxidation. Protective effects on peroxyl and hydroxyl radical-induced DNA strand damages were observed in all tested garlic cloves. These results indicate growing conditions of garlic cloves affect total thiosulfinate content and antioxidant activities.

  • 주제어

    garlic .   antioxidant activity .   LDL oxidation .   DNA strand damage.  

  • 참고문헌 (52)

    1. Free radicals in the physiological control of cell function , Droge, W. , Physiol. Rev. / v.82,pp.47-95,
    2. The characterization of antioxidants , Halliwell, B.;Aeschbach, R.;Loliger, J.;Aruoma, O.I. , Food Chem. Toxicol. / v.33,pp.601-617,
    3. Flavonoid as antioxidants , Pieta, P.G. , J. Nat. Prod. / v.63,pp.1035-1042,
    4. Natural antioxidants from residual sources , Moure, A.;Cruz, J.M.;Franco, D.;Domingues, J.M.;Sineiro, J.;Domfngues, H.;Nunez, M.J.;Parajo, J.C. , Food Chem / v.72,pp.145-171,
    5. The pathogenesis of atherosclerosis: A perspective for the 1990s , Ross, R. , Natrrre / v.362,pp.801-809,
    6. Beyond cholesterol modification of low density lipoprotein that increase its atherogenicity , Steinberg, D.;Parthasarathy, S.;Carew, T.E.;Khoo, J.C.;Witztem, J.L. , New Engl. J. Med. / v.320,pp.3603-3608,
    7. Effect of hydroxytyrosol found in extra virgin olive oil on oxidative DNA damage and low-density lipoprotein oxidation , Aruoma, O.I.;Deiana, M.;Jenner, A.;Haliwell, B.;Kaur, H.;Banni, S.;Corongiu, F.P.;Dessi, M.A.;Aeschbach, R. , J. Agric. Food Chem. / v.46,pp.5181-5187,
    8. Garlic: A review of its medicinal effects and indicated active compounds;Phytomedicines of Europe: their Chemistry and Biological Activity , Lawson, L.D.;Lawson, L.D.(ed.);Bauer, R.(ed.) , / v.,pp.176-209,
    9. Allum sativum (garlic) and cancer prevention , Lau, B.H.S.;Tadi, P.P.;Tosk, J.M. , Nutr. Res. / v.10,pp.937-948,
    10. Differential induction of NAD(P)H quinine oxidoreductase by anticarcinogenic organosulfides from garlic , Singh, S.V.;Pan, S.S.;Srivatava, S.K.;Xia, H.;Hu, X.;Zaren, H.A.;Orchard, J.L. , Biochim. Biophys. Res. Commun. / v.244,pp.917-920,
    11. Immunomodulation and antitumor activities of aged garlic extract , Kyo, E.;Uda, N.;Suzuki, A.;Kakimoto, M.;Ushujima, M.;Kasuga, S.;ltakura, Y. , Phytomedicine / v.5,pp.259-267,
    12. Effects of garlic preparations on superoxide production by phorbol ester activated granulocytes , Siegers, C.P.;Robke, A.;Pentz, R. , Phytomedicine / v.6,pp.13-16,
    13. Antimutagenic effects of ajoene, an organosulfur compound derived from garlic , Ishikawa, K.;Naganawa, R.;Yoshida, H.;Iwata, N.;Fukuda, H.;Fujino, T.;Suzuki, A. , Biosci. Biotechnol. Biochem. / v.60,pp.2086-2088,
    14. Effect of garlic supplementation to cholesterol-rich diet on development of atherosclerosis in rabbits , Mirhadi, S.A.;Singh, S. , Ind. J. Exp. BioI. / v.29,pp.162-168,
    15. Inhibitiors of platelet aggregation generated from mixtures of Allium species and/or SAlk(en)yl-L-cysteine sulfoxide , Morimitsu, Y.;Morioka, Y.;Kawakishi, S. , J. Agric. Food Chem. / v.40,pp.368-372,
    16. Vitro virucidal effects of Allium sativum (garlic) extract and compounds , Weber, N.D.;Anderson, D.O.;North, J.A.;Murray, B.K.;Lawson, L.D.;Hughes, B.G. , Planta. Med. / v.58,pp.417-423,
    17. Physiological activity of Alliin and ethanol extract from Korean garlic (Allium sativum L.) , Lim, S.W.;Kim, T.H. , Korean J. Food Sci. Technol / v.29,pp.348-354,
    18. Antioxidant activity of allicin, an active principle in garlic , Prasad, K.;Laxdal, V.A.;Yu, M.;Raney, B.L. , Mol. Cell. Biochem. / v.148,pp.183-189,
    19. Antioxidant activity of several Allium members , Yin, M.C.;Cheng, W.S. , J. Agric. Food Chem. / v.46,pp.4097-4101,
    20. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins , Rabinkov, A.;Miron, T.;Konstantinovski, I.;Wilchek, M.;Mirelman, D.;Weiner, L. , Biochem. Biophys. Acta / v.1379,pp.233-244,
    21. High correlation between lipid peroxide radical and tumor-promoter effect: suppression of tumor promotion in the Epstein-Barr virus/B-lymphocyte system and scavenging of alkyl peroxide radicals by various vegetables extracts , Maeda, H.;Katsuki, T.;Akaike, T.;Yasutake, R. , Jpn. J. Cancer Res. / v.52,pp.923-928,
    22. Free radicals, antioxidants, and human diseases: where are we now? , Halliwell, B.;Gutteridge, J.M.C.;Corss, E.E.J. , J. Lab. Clin. Med. / v.119,pp.598-620,
    23. The approach to understanding aromatic hydrogencarbon carcinogenesis. The central role of radical cations in metabolic action , Cvalieri, E.L.;Rogan, E.G. , Pharmacol. Ther. / v.55,pp.183-199,
    24. Modulation of platelet function by free radicals and free-radical scavengers , Savemini, D.;Botting, R. , Trends Pharmacol. Sci. / v.14,pp.36-42,
    25. Effects on active oxygen species of alliin and Allium sativum (garlic) powder , Kourounakis, P.N.;Rekka, E.A. , Res. Commun. Chem. Pathol. Pharmacol. / v.74,pp.249-252,
    26. Investigation of the molecular mechanism of the antioxidant activity of some Allium sativum ingredients , Rekka, E.A.;Kourounakis, P.N. , Pharmazie / v.49,pp.539-540,
    27. Antioxidant functions of selected Allium thiosulfinates and S-alk(en)yl-L-cysteine sulfoxides , Xiao, H.;Parkin, K.L. , J. Agric. Food Chem. / v.50,pp.2488-23493,
    28. Effects of extraction conditions on the functional properties of garlic extracts , Byun, P.H.;Kim, W.J.;Yoon, S.K. , Korean J. Food Sci. Technol. / v.33,pp.507-513,
    29. A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates , Miron, T.;Shin, I.;Feigenblat, G.;Weiner, I.;Mirelman, D.;Wilchek, M.;Rabinkov, A. , Anal. Biochem. / v.307,pp.76-83,
    30. Antioxidative properties of histidine-containing peptides designed from peptide fragments found in the digests of a soybean protein , Chen, H.M.;Muramoto, K.;Yamauchi, F.;Fujimoto, K.;Nokihara, K. , J. Agric. Food Chem. / v.46,pp.49-53,
    31. Convenient assays for superoxide dismutase;CRC handbook of free radicals and antioxidants in biomedicine , Leopold, F.;Reinhard, B.;Regina, B.;Edmund, I.;Fritz, O.;Mquel, J.(ed.) , / v.,pp.287-293,
    32. Scavenging effect of methanolic extracts of peanut hulls on free radical and active oxygen species , Yen, G.C.;Duh, P.D. , J. Agric. Food Chem. / v.42,pp.629-632,
    33. Role of ferritine as a lipid oxidation catalyst in muscle food , Decker, E.A.;Welch, B. , J. Agric. Food Chem. / v.38,pp.674-677,
    34. Antioxidant activity of enzymatic hydrolysates from whelk (Buccinum middendorffiverkrii) internal organ , Son, M.R.;Park, J.H.;Lee, S.C. , Food Sci. Biotechnol. / v.12,pp.683-686,
    35. Evaluation of antioxidant activity of epigallocatechin gallate in biphasic model systems in vitro , Hu, C.;Kittts, D.D. , Mol. Cell. Biochem. / v.218,pp.147-155,
    36. Antioxidant activity of a Rhus vemiciflua Stokes ethanol extract , Lim, K.T.;Hu, C.;Kitts, D.D. , Food Chem. Toxicol. / v.39,pp.229-237,
    37. Antioxidant activity of extracts from Acacia confuse bark and heartwood , Chang, S.T.;Wu, J.H.;Wang, S.Y.;Kang, P.I.;Yang, N.S.;Shyur, L.F. , J. Agric. Food Chem. / v.49,pp.3420-3424,
    38. Quantitative determination of allicin in garlic: supercritical fluid extraction and standard addition of alliin , Rybak, M.E.;Calvey, E.M.;Hamly, J.M. , J. Agric. Food Chem. / v.52,pp.682-687,
    39. Bioactive compounds of garlic and garlic products;ACS Symposium Series 534, Human Medicinal Agents from Plants , Lawson, L.D.;Kinghorn, A.D.(ed.);Balandrin, M.F.(ed.) , / v.,pp.306-330,
    40. Nonenzymatic antioxidant of four organosulfur compounds derived from garlic , Yin, N.C.;Hwang, S.W.;Chan, K.C. , J. Agric. Food Chem. / v.50,pp.6143-6147,
    41. The mechanism of antioxidant action in vitro;Food antioxidants , Gordon, M.R.;Hudson, B.J.F.(ed.) , / v.,pp.1-18,
    42. Will the good fairies prove us that vitamin E lessens human degenerative disease? , Diplock, A.T. , Free Radic. Res. / v.27,pp.511-532,
    43. Antioxidant and prooxidant activities of elderberry (Sambucus nigra) extraction in low-density lipoprotein oxidation , Abuja, M.P.;Murkovic, M.;Pfannhauser, M. , J. Agric. Food Chem. / v.46,pp.4091-4096,
    44. Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships , Cao, G.;Sofic, E.;Prior, R.L. , Free Radic. BioI. Med. / v.22,pp.749-760,
    45. Effects of flavonoids on the oxidation of low-density lipoprotein;Flavonoids in health and disease , Leake, D.S.;Rice-Evans, C.(ed.);Packer, L.(ed.) , / v.,pp.253-276,
    46. Measurement of oxidizability of blood plasma , Kontush, A.;Beisiegel, U. , Methods Enzymol. / v.299,pp.35-49,
    47. Antioxidant effects of phenolic rye (Secaie cereaie L.) extracts, monomeric hydroxycinnamates, and ferulic acid dehydrodimers on human low density lipoproteins , Andreason, M.;Landbo, A.K.;Christensen, L.P.;Hansen, A.;Meyer, A.S. , J. Agric. Food Chem. / v.49,pp.4090-4096,
    48. Antioxidative activity of sulfur-containing compounds in Allium species for human lowdensity lipoprotein (LDL) oxidation in vitro , Higuchi, O.;Tateshita, K.;Nishimura, H. , J. Agric. Food Chem. / v.51,pp.7208-7214,
    49. Antioxidative and antiglycative effects of six organosulfur compounds in low-density lipoprotein and plasma , Huang, C.N.;Homg, J.S.;Yin, M.C. , J. Agric. Food Chem. / v.52,pp.3674-3678,
    50. Antioxidant activity of anthocyanins and their aglycones , Kahkonen, M.P.;Heinonen, M. , J. Agric. Food Chem. / v.51,pp.328-633,
    51. Factors affecting DNA damage caused by lipid hydroperoxides and aldehydes , Yang, M.R.;Schaich, K.M. , Free Radic. BioI. Med. / v.20,pp.225-236,
    52. Antioxidant activity and protective effect on DNA cleavage ofresveratrol , Acquavita, R.;Campisi, A.;Sorrenti, V.;Di Giacomo, C.;Barcellona, M.L.;Avitabile, M.;Vanella, A. , J. Food Sci. / v.67,pp.137-141,
  • 이 논문을 인용한 문헌 (22)

    1. 2006. "" Food science and biotechnology, 15(1): 158~161     
    2. 2006. "" Food science and biotechnology, 15(3): 329~338     
    3. 2006. "" Food science and biotechnology, 15(3): 482~484     
    4. 2006. "" Food science and biotechnology, 15(4): 511~515     
    5. 2007. "" Food science and biotechnology, 16(6): 963~966     
    6. 2007. "" Food science and biotechnology, 16(5): 796~801     
    7. 2007. "" Food science and biotechnology, 16(5): 822~827     
    8. 2007. "" Food science and biotechnology, 16(5): 858~862     
    9. 2007. "" Food science and biotechnology, 16(2): 223~227     
    10. 2008. "" Journal of food science and nutrition, 13(4): 327~333     
    11. 2008. "" Journal of food science and nutrition, 13(4): 334~339     
    12. Chung, Ji-Young ; Kim, Chang-Soon 2008. "Antioxidant Activities of Domestic Garlic (Allium sativum L.) Stems from Different Areas" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 37(8): 972~978     
    13. 2008. "" Food science and biotechnology, 17(1): 38~45     
    14. Chung, Ji-Young ; Kim, Chang-Soon 2009. "Antioxidant Activities of Domestic Garlic (Allium sativum L.) Stems and Garlic Bulbs according to Cooking Methods" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 38(2): 188~194     
    15. 2009. "" Food science and biotechnology, 18(1): 143~149     
    16. 2009. "" Food science and biotechnology, 18(1): 239~244     
    17. 2009. "" Biomolecules & therapeutics, 17(2): 199~204     
    18. 2009. "" Food science and biotechnology, 18(5): 1279~1283     
    19. 2010. "" Biomolecules & therapeutics, 18(4): 433~441     
    20. Lee, Youn-Ri ; Woo, Koan-Sik ; Hwang, In-Guk ; Kim, Hyun-Young ; Lee, Sang-Hoon ; Lee, Jun-Soo ; Jeong, Heon-Sang 2012. "Physicochemical Properties and Antioxidant Activities of Garlic (Allium sativum L.) with Different Heat and Pressure Treatments" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 41(2): 278~282     
    21. Jung, Kyungae ; Park, Chan-Sung 2013. "Antioxidative and Antimicrobial Activities of Juice from Garlic, Ginger, and Onion" 한국식품저장유통학회지 = Korean journal of food preservation, 20(1): 134~139     
    22. Yoon, Hwan-Sik ; Kang, Min-Jung ; Hwang, Cho-Rong ; Sim, Hye-Jin ; Kim, Gyeong-Min ; Shin, Jung-Hye 2014. "Physicochemical characteristics of garlic (Allium sativum L.) shoots from different areas in Namhae" 한국식품저장유통학회지 = Korean journal of food preservation, 21(3): 321~327     

 저자의 다른 논문

  • Kim, Kwan-Soo (1)

    1. 2004 "Effects of Chitosan and Lactic Acid on Enzymatic Activities and Bioactive Compounds during Germination of Black Rice" Journal of food science and nutrition 9 (3): 199~205    
  • Jang, Hae-Dong (16)

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역


  • NDSL :

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기