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Asian-Australasian journal of animal sciences v.18 no.4, 2005년, pp.458 - 462   피인용횟수: 1

Association between PCR-RFLP Polymorphism of the Fifth Intron in Lipoprotein Lipase Gene and Productive Traits in Pig Resource Family

Zhang, B.Z.    (Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agriculture University   ); Lei, M.G.    (Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agriculture University   ); Deng, C.Y.    (Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agriculture University   ); Xiong, Y.H.    (Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agriculture University   ); Zuo, B.    (Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agriculture University   ); Li, F.E.    (Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agriculture University  );
  • 초록

    The study was aimed at detecting polymorphism of the fifth intron in lipoprotein lipase (LPL) gene and analyzing association between the polymorphism and productive traits. A pair of primers was designed for amplifying the fifth intron. Sequence analysis indicated that a G1171C substitution existed in Large White breed. The mutation was detected by PCR-AfaI-RFLP. Polymorphism analysis in a pig resource family showed that there existed significant effects on carcass and meat quality traits. Thoraxwaist fat thickness of BB genotype was significantly higher (14.2%, p


  • 주제어

    Association .   Productive Traits .   Polymorphism .   Lipoprotein Lipase Gene .   Pigs.  

  • 참고문헌 (17)

    1. Chamberlain, J. C., J. A. Thorn, K. Oka and Galton. 1989. DNA polymorphisms at the lipoprotein lipase gene: associations in normal and hypertriglyceridaemic subjects. Atherosclerosis 79:85-91. 
    2. Harbitz, I., M. Langset and A. G. Ege. 1999. The porcine hormonesensitive lipase gene: sequence, structure, polymorphisms and linkage mapping. Anim. Gene. 30:10-15. 
    3. Hokanson, J. E., J. D. Brunzell, G. P. Jarvik and E. M. Wijsman. 1999. Linkage of low-density lipoprotein size to the lipoprotein lipase gene in heterozygous lipoprotein lipase deficiency. J. Human Gene. 64:608-618. 
    4. Wu, Z. F. 1998. Molecular analyzing of porcine lipoprotein lipase and hormone-sensitive lipase gene. Ph.D. Thesis, Hua zhong Agricultire University, Wuhan. 
    5. Zhang, H., H. Henderson and S. E. Gagne. 1996. Common sequence variants of lipoprotein lipase: standardized studies of in vitro expression and catalytic function. Biochim. Biophys. Acta. 1302:159-166. 
    6. Zuo, B., Y. Z. Xiong, Y. H. Su, C. Y. Deng, R. Zheng and S. W. Jiang. 2003. Mapping quantitative trait loci meat quality on pig chrosomone 3, 4 and 7. Asian-Aust. J. Anim. Sci. 16:320-324. 
    7. Hokanson, J. E. 1997. Lipoproteinlipase gene variants and risk of coronary disease: a quantitative analysis of population-based studies. J. Clinical Lab. Res. 27:24-34. 
    8. Minkema, D., G. Eikelenboom and P. Eldik. 1976. Inheritance of MH-susceptibility in pigs. In: Proceedings of the 3rd International Conference on Production Disease in Farm Animals. pp. 203-207. 
    9. Ahn, Y. I., C. Kamboh and R. F. Hamman. 1993. Two DNA polymorphisms in the lipoprotetin lipase gene and their association with factors related to cardiovascular diease. J. Lipid Res. 34:421-428. 
    10. Archibald, A. L. 1994. Livestock genetics: fat pigs can blame their genes. Current Biology 4:728-30. 
    11. Padma, B., P. Kumar, V. Choudhary, S. K. Dhara, A. Mishra, T. K. Bhattacharya, B. Bhushan and A. Sharma. 2004. Nucleotide sequencing and PCR-RFLP of insulin-like growth factor binding protein-3 gene in Riverine Buffalo (Bubalus bubalis). Asian-Aust. J. Anim. Sci. 17(7):910-913. 
    12. Simpson, S. P. and A. J. Webb. 1989. Growth and carcass performance of British Landrace pigs heterozygous at the halothane locus. Anim. Prod. 49:503-509. 
    13. Dichek, H. L., S. S. Fojo and O. U. Beg. 1991. Identification of two separate allelic mutations in the lipoprotein lipase gene of a patient with the familial hyperchylomicronemia syndrome. J. Biochem. Chem. 266(1):473-477. 
    14. Gu, F. and I. Harbitz. 1992. Mapping of the porcine lipoprotein lipase (LPL) gene to chromosome $14^{q12-q14}$ by in situ hybridization. Cytogenet Cell Genet 59(1):63-64. 
    15. Sambrook, J., E. F. Fritsch and T. Maniatis. 1989. Molecular cloning: A laboratory manual. Ed 2nd, Vol 3. Cold Spring Harbor Laboratory Press. New York. 
    16. Xiong, Y. Z. and C. Y. Deng. 1999. Technical testing rule of lean pig. Chinese Agricultural Press, Beijing. 
    17. Liu, B. H. 1998. Statistical genomics: linkage, mapping, and QTL analysis. CRC Press, LLC. 
  • 이 논문을 인용한 문헌 (1)

    1. 2007. "" Asian-Australasian journal of animal sciences, 20(11): 1651~1654     

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