본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

특발성 간질성 폐렴의 영상 소견
Radiologic Findings of Idiopathic Interstitial Pneumonia

박재성    (순천향대학교 의과대학 방사선과학교실  );
  • 초록

    특발성 간질성 폐렴은 폐포보다는 폐간질을 주로 침범하는 미만성 염증성 섬유화 병변으로 병변의 분류에 임상적 및 병리학적으로 많은 혼동과 변화를 겪어왔다. 최근에는 미국흉부학회와 유럽호흡기학회의 공동 모임에서 이 질환 군에 해당되는 모든 임상과들이 모여서 7가지의 병변으로 재분류 하였는데, 이는 Idiopathic pulmonary fibrosis, Nonspecific interstitial pneumonia, Cryptogenic organizing pneumonia, Acute interstitial pneumonia, Respiratory bronchiolitis interstitial lung disease, Desquamative interstitial pneumonia, Lymphocytic interstitial pneumonia 등이다. 이에 저자는 최근 분류에 의한 특발성 간질성 폐렴의 7가지 병변을 영상 소견을 중심으로 기술하고자 한다.


  • 참고문헌 (57)

    1. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. Am J Respir Crit Care Med 2000;161:646-64 
    2. Nagai S, Kitaichi M, Hamada K, Nagao T, Hoshino Y, Miki H, et al. Hospital-based historical cohort study of 234 histologically proven Japanese patients with IPF. Sarcoidosis Vasc Diffuse Lung Dis 1999;16:209-14 
    3. Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 2001;134:136-51 
    4. Wells AU, Hansell DM, Rubens MB, Cullinan P, Haslam PL, Black CM, et al. Fibrosing alveolitis in systemic sclerosis: bronchoalveolar lavage findings in relation to computed tomographic appearance. Am J Repir Crit Care Med 1994;150:462-8 
    5. Katzenstein AL, Myers JL. Idiopathic pulmonary fibrosis: clinical relevance of pathologic classification. Am J Respir Crit Care Med 1998;157:1301-15 
    6. Raghu G, Mageto YN, Lockhart D, Scmidt RA, Wood DE, Godwin JD. The accuracy of the clinical diagnosis of new-onset idiopathic pulmonary fibrosis and other interstitial lung disease: a prospective study. Chest 1999:116:1168-74 
    7. Park JS, Lee KS, Kim JS, Park CS, Choi DL, Kim KJ, et al. Nonspecific interstitial pneumonia with fibrosis: radiographic and CT findings in seven patients. Radiology 1995;195:645-8 
    8. Park CS, Chung SW, Lim GI, Uh ST, Kim YH, Park JS, et al. Increased levels of interleukin-6 are associated with lymphocytosis in bronchoalveolar lavage fluids of idiopathic nonspecific interstitial pneumonia. Am J Respir Crit Care Med 2000:162:1162-8 
    9. Hartman TE, Swensen SJ, Hansell DM, Colby TV, Myers JL, Tazelaar HD, et al. Nonspecific interstitial pneumonia: variable appearance at high-resolution chest CT. Radiology 2000;217:701-5 
    10. Costabel U, Teschler H, Guzman J. Bronchiolitis obliterans organizing pneumonia (BOOP): the cytological and immunocytologic profile of bronchoalveolar lavage. Eur Respir J 1992;5:791-7 
    11. Muller NL, Guerry-Force ML, Staples CA, Wright JL, Wiggs B, Coppin C, et al. Differential diagnosis of bronchilitis obliterans with organizing pneumonia and usual interstitial pneumonia: clinical, functional and radiologic findings. Radiology 1987;162:151-6 
    12. Primack SL, Hartman TE, Ikezoe J, Akira M, Sakatani M, Muller NL. Acute interstitial pneumonia: radio-graphic and CT findings in nine patients. Radiology 1993;188:817-20 
    13. King TE Jr. Respiratory bronchiolitis-associated inter-stitial lung disease. Clin Chest Med 1993;14:693-8 
    14. Carrington CB, Gaensler EA, Coutu RE, FitzGerald MX, Gupta RG. Natural history and treated course of usual and desquamative interstitial pneumonia. N Engl J Med 1978;298:801-9 
    15. Yousem SA, Colby TV, Gaensler EA. Respiratory bronchiolitis-associated interstitial lung disease and its relationship to desquamative interstitial pneumonia. Mayo Clin Proc 1989;64:1373-80 
    16. Feigin DS, Friedman PJ. Chest radiography in desquamative interstitial pneumonitis: a review of 37 patients. Am J Roentgenol 1980;134:91-9 
    17. Yousem SA, Colby TV, Carrington CB. Follicular bronchiolitis/bronchiolitis. Hum Pathol 1985;16:700-6 
    18. Julsrud PR, Brown LR, Li CY, Rosenow EC 3rd, Crowe JK. Pulmonary processes of mature-appearing lymphocytes: pseudolymphoma, well-differentiated lymphocytic lymphoma, and lymphocytic interstitial pneumonitis. Radiology 1978;127:289-96 
    19. Lee KS, Kulling P, Hartman TE, Muller NL. Cryptogenic organizing pneumonia: CT findings in 43 patients. Am J Roentgenol 1994;162:543-6 
    20. Akira M, Yamamoto S, Sakatani M. Bronchiolitis obliterans organizing pneumonia manifesting as multiple large nodules or masses. Am J Roentgenol 1998;170:291-5 
    21. Liebow AA, Steer A, Billingsley JG. Desquamative interstitial pneumonia. Am J Med 1965;39:369-404 
    22. Muller NL, Miller RR, Webb WR, Evans KG, Ostrow DN. Fibrosing alveolitis: CT-pathologic correlaton. Radiology 1986;160:585-8 
    23. Groskin S. Chronic interstitial lung disease. In: Heitzmans' the lung: radiologic-pathologic correlation. St Louis: Mosby-Year Book; 1983. p. 235-359 
    24. Cushley MJ, Davison AG, du Bois RM, Egan J, Flower CD, Gibson GJ, et al. The diagnosis, assessment and treatment of diffuse parenchymal lung disease in adults. Thorax 1999;54:S1-14 
    25. Olson J, Colby TV, Elliott CG. Hamman-Rich syndrome revisited. Mayo Clin Proc 1990;65:1538-48 
    26. Katsenstein AL, Fiorelli RF. Nonspecific interstitial pneumonia/fibrosis: histologic features and clinical significance. Am J Surg Pathol 1994;18:136-47 
    27. Primack SL, Hartman TE, Ikezoe J, AkiraM, Sakatani M, Muller NL. Acute interstitial pneumonia: radio-graphic and CT findings in nine patients. Radiology 1993;188:817-20 
    28. MacDonald SL, Rubens MB, Hansell DM, Colby TV, du Bois RM, Nicholson AG, et al. Nonspecific inter-stitial pneumonia and usual interstitial pneumonia:comparative appearances and diagnostic accuracy of high-resolution computed tomography. Radiology 2001;221:600-5 
    29. Kondoh Y, Taniguchi H, Kawabata Y, Yokoi T, Suzuki K, Takagi K. Acute exacerbation in idiopathic pulmonary fibrosis: analysis of clinical and pathologic findings in three cases. Chest 1993;103:1808-12 
    30. King TE Jr, Mortenson RL. Cryptogenic organizing pneumonitis. Chest 1992;102:8S-13S. 
    31. Desai SR, Wells AU, Rubens MB, Evans TW, Hansell DM. Acute respiratory distress syndrome: CT abnormalities at long-term follow-up. Radiology 1999;210:29-35 
    32. Nishimura K, Kitaichi M, Izumi T, Nagai S, Kanaoka M, Itoh H. Usual interstitial pneumonia: histologic correlation with high-resolution CT. Radiology 1992;182-337-42 
    33. Hunninghake GW, Zimmerman MB, Schwarts DA, King TE Jr, Lynch D, Hegele R, et al. Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2001:164:193-6 
    34. Akira M, Hamada H, Sakatani M, Kobayashi C, Nishioka M, Yamamoto S. CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis. Am J Roentgenol 1997;168:79-83 
    35. Kim TS, Lee KS, Chung MP, Park JS, Hwang JH, Kwon OJ, et al. Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings. Am J Roentgenol 1998;171:1645-50 
    36. Strimlan CV, Rosenow EC 3rd, Weiland LH, Brown LR. Lymphocytic interstitial pneumonitis: review of 13 cases. Ann Intern Med 1978;88:616-21 
    37. Johkoh T, Muller NL, Pickford HA, Hartman TE, Ichikado K, Akira M, et al. Lymphocytic interstitial pneumonia: thin-section CT findings in 22 patients. Radiology 1999;212:567-72 
    38. The BAL Cooperative Group Steering Committee. Bronchoalveolar lavage constituents in healthy Individuals, idiopathic pulmonary fibrosis, and selected comparison groups. Am Rev Respir Dis 190;141:S169-202 
    39. Katzenstein AL, Myers JL, Mazur MT. Acute interstitial pneumonia: a clinicopathlogic, ultrastructural, and cell kinetic study. Am J Surg Pathol 1986;10:256-67 
    40. Cordier JF, Loire R, Brune J. Idiopathic bronchiolitis obliterans organizing pneumonia: definition of characteristic clinical profiles in a series of 16 patients. Chest 1989;96:999-1004 
    41. Liebow AA, Carrington CB. The interstitial pneumonias. In: Simon M, Potchen EJ, LeMay M, editors. Frontiers of pulmonary radiology, 1st ed. New York: Grune & Stratton; 1969. p. 102-41 
    42. Turner-Warwick M. Burrows B, Johnson A. Cryptogenic fibrosing alveolitis: clinical features and their influence on survival. Thorax 1980;35:171-80 
    43. Hartman TE, Primack SL, Swensen SJ, Hansell D, McGuinness G, Muller NL. Desquamative interstitial pneumonia: thin-section CT findings in 22 patients. Radiology 1993;187:787-90 
    44. Kradin RL, Young RH, Kradin LA, Mark EJ. Immunoblastic lymphoma arising in chronic lymphoid hyperplasia of the pulmonary interstitium. Cancer 1982;50:1339-43 
    45. Gruden JF, Webb WR. CT findings in a proved case of respiratory bronchiolitis. Am J Roentgenol 1993; 161:44-6 
    46. American Thoracic Society, European Respiratory Society. American Thoracic Society and the European Respiratory Society International Multidisciplinary Consensus Classification of Idiopathic Interstitial Pneumonia. Am J Respir Crit Care Med 2002;165:277-304 
    47. Nishimura K, Itoh H. High-resolution computed tomographic features of bronchiolitis obliterans organizing pneumonia. Chest 1992;102:26S-31S 
    48. Tubbs RR, Benjamin SP, Reich NE, McCormack LJ, van Ordstrand HS. Desquamative interstitial pneumonitis: cellular phase of fibrosing alveolitis. Chest 1977;72:159-65 
    49. Hartman TE, Primack SL, Kang EY, Swensen SJ, Hansell DM, McGuinness G, et al. Disease progression in usual interstitial pneumonia compared with desquamative interstitial pneumonia: assessment with serial CT. Chest 1996;110:378-82 
    50. Ichikawa Y, Kinoshita M, Koga T, Oizumi K, Fujimoto K, Hayabuchi N. Lung cyst formation in lymphocytic interstitial pneumonia: CT features. J Comput Assist Tomogr 1994;18:745-8 
    51. Kitaichi M. Pathologic features and the classification of interstitial pneumonia of unknown etiology. Bull Chest Dis Res Inst Kyoto Univ 1990;23:1-18 
    52. Park JS, Brown KK, Tuder RM, Hale VA, King TE Jr, Lynch DA. Respiratory bronchiolitis-associated interstitial lung disease: radiologic features with clinical and pathologic correlation. J Comput Assist Tomogr 2002;26:13-20 
    53. Staples CA, Muller NL, Vedal S, Abboud R, Ostrow D, Miller RR. Usual interstitial pneumonia: cor- relation of CT with clinical, functional, and radiologic findings, Radiology 1987;162:377-81 
    54. Izumi T, Kitaichi M, Nishimura K, Nagai S. Bronchiolitis obliterans organizing pneumonia. Chest 1992;102:715-9 
    55. Muller NL, Staples CA, Miller RR. Bronchiolitis obli- terans organizing pneumonia: CT features in 14 patients. Am J Roentgenol 1990;154:983-7 
    56. Akira M, Sakatani M, Ueda E. Idiopathic pulmonary fibrosis: progression of honeycombing at thin-section CT. Radiology 1993;189:687-91 
    57. Heyneman LE, Ward S, Lynch DA, Remy-Jardin M, Johkoh T, Muller NL. Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? Am J Roentgenol 1999;173:1617-22 

 저자의 다른 논문

  • 박재성 (22)

    1. 1991 "공허안(empty sella): MRI상 발생 빈도와 그 의의" 대한방사선의학회지 = Journal of the Korean Radiological Society 27 (6): 773~777    
    2. 1995 "폐섬유화정에서 고해상 CT의 추적평가 및 폐기능 검사와 기관지 폐포 세척액과의 상관관계" 대한방사선의학회지 = Journal of the Korean Radiological Society 33 (2): 215~220    
    3. 1995 "다발성 근염에 동반된 Diffuse Alveolar Damage 1예" 결핵 및 호흡기 질환 = Tuberculosis and respiratory diseases 42 (3): 400~406    
    4. 1996 "미만성 침윤성 폐질환의 진단: HRCT와 단순흉부X선사진의 비교" 결핵 및 호흡기 질환 = Tuberculosis and respiratory diseases 43 (3): 388~402    
    5. 1997 "기관지 천식 환자에서 치료 반응의 차이에 따른 폐 기능 및 고해상 CT 소견의 고찰" 결핵 및 호흡기 질환 = Tuberculosis and respiratory diseases 44 (5): 1051~1062    
    6. 1998 "폐자궁내막증(Pulmonary endometriosis)의 방사선학적 소견" 대한방사선의학회지 = Journal of the Korean Radiological Society 39 (6): 1107~1111    
    7. 2005 "기관지 천식의 영상 소견" Tuberculosis and respiratory diseases : TRD = 결핵 및 호흡기 질환 59 (6): 591~599    
    8. 2005 "기관과 대장에 발생한 원발성 mucosa-associated lymphoid tissue 림프종 1예" Tuberculosis and respiratory diseases : TRD = 결핵 및 호흡기 질환 59 (2): 193~197    
    9. 2006 "6 - Sigma 경영혁신기법 시행에 따른 방사선과 내부고객만족도의 변화" 한국의료QA학회지 = Journal of Korean Society of Quality Assurance in Health Care 12 (1): 78~90    
    10. 2006 "입원 소아환자에서 정맥주사 시 통증 및 불안을 경감시키기 위한 중재연구" 한국의료QA학회지 = Journal of Korean Society of Quality Assurance in Health Care 12 (1): 92~102    

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • NDSL :
  • 대한결핵 및 호흡기학회 : 저널
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기