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상피세포에 대한 Weissella cibaria 유산균의 부착력에 영향을 미치는 인자
Adhesion of Weissella cibaria to the Epithelial Cells and Factors Affecting its Adhesion

강미선    (전남대학교 의과대학 미생물학교실   ); Piao, MeiShan    (전남대학교 의과대학 미생물학교실   ); 신부안    (전남대학교 의과대학 미생물학교실   ); 이현철    (전남대학교 의과대학 미생물학교실   ); 오종석    (전남대학교 의과대학 미생물학교실  );
  • 초록

    We evaluated the ability of lactic acid bacteria, Weissella cibaria, isolated from the oral cavity to adhere to epithelial cells. W cibaria efficiently adhered to KB cells and HeLa cells. In addition, W. cibaria efficiently adhered to Fusobacterium nucleatum. But the adhesiveness of W. cibaria disappeared upon exposure to LiCl or pronase, suggesting that the S-layer proteins of W. cibaria mediated the adhesiveness. The molecular mass of the S-layer proteins extracted from W cibaria was approximately 50 kDa. When W. cibaria strains were washed with 0.45% saline, the bacteria were efficiently adhered to the epithelial cells. In conclusion, W. cibaria has the ability to adhere to epithelial cells through the S-layer proteins.


  • 주제어

    Adhesion .   Weissella cibaria .   KB cell .   HeLa cell .   Fusobacterium mucleatum.  

  • 참고문헌 (27)

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