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일정 전기자극하의 근력 상승 - 전기 자극 파형의 펄스 진폭과 펄스폭에 대한 의존성
Muscle Force Potentiation During Constant Electrical Stimulation - Dependence on Pulse-Amplitude and Pulse-Duration of Electrical Stimulation

김지원   (건국대 의료생명대 의학공학부UU0000050  ); 강민영   (건국대 의료생명대 의학공학부UU0000050  ); 엄광문   (건국대 의료생명대 의학공학부UU0000050  );
  • 초록

    The purpose of this work is to investigate the fundamental properties of the gradual muscle force potentiation. We investigated the dependence of force potentiation on both the pulse-amplitude and the pulse-duration with different ramp-up time. The experimental results showed that the force increment ratio (FIR) during constant electrical stimulation decreased with pulse-amplitude and also with pulse-duration. The FIR was greater with short ramp-up time in both the pulse-amplitude and pulse-width modulation. The feasible mechanism might be that the myosin light chain phosphorylation induces the force potentiation and it occurs only in the fast type muscle fibers which are recruited first. These observations indicate that muscle potentiation must be understood well for the accurate control of muscle force.


  • 주제어

    Functional Electrical Stimulation .   Muscle Force Potentiation .   Stimulation Current .   Pulse-Duration.  

  • 참고문헌 (16)

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    2. G. Eorm, T. Watanabe, N. Hoshmiya. G. Khang, 'Gradual potentiation of isometric muscle force during constant electrical stimulation,' Medical & Biomedical Engineering & Computing , pp. 137-142, 2000 
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    4. B.O. Kim, Personal communication, Choongnam Univ., Korea, 2000 
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    11. C.K. Thomas, G. Nelson, L. Than, I. Zijdewind. 'Motor unit activation order during electrically evoked contractions of paralyzed or partially paralyzed muscles,' Muscle Nerve, Vol. 25, pp. 797 - 804, 2002 
    12. B. B. Adlhikari, J. Somerset, J.T. Stull, and P.G. Fajer, 'Dynamic modulation of the requlatory domain of myosin heads by pH, ionic strength, and RLC Phosphorylation in synthetic mysin filaments,' Biochemistry, Vol. 38, pp. 3127-3132, 1999 
    13. H.L. Sweeney, B.F. Bowman and J.T. Stull, 'Myosin light chain phosphorylation in vertebrate striated muscle: regulation and function,' American J.Physiol. Cell Physiol., Vol. 264, pp. C1085 - C1095, 1993 
    14. R.L. Moore, and J.T. Stull, 'Myosin light chain phosphorylation in fast and slow skeletal muscles in situ,' Am. J.Physiol., Vol. 247, pp. 462 - 471, 1984 
    15. E. Patrick. P. Crago,. Hunter Peckham, B. Geoffrey, Thrope. 'Modulation of Muscle Force by Recruitment During Intramuscular Stimulation,' IEEE Trans. Biomed Eng., vol. BME-27, No.12, pp.679 - 684 December, 1980 
    16. E.M. Houston, J. H. Green, T. James. Stull, ' Myosin light chain phosphorylation and isometric twitch potentication in intact human muscle,' Pflugers Archiv, Vol. 403, pp. 348 - 352, 1985 

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