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촉지 림프절의 세침흡인 세포검사 - 단일 기관의 1,346예 경험 -
Fine Needle Aspiration Cytology of Palpable Lymph Nodes -A Single Institutional Experience of 1,346 Cases-

신동훈    (부산대학교 의학전문대학원 병리학교실   ); 김지연    (부산대학교 의학전문대학원 병리학교실   ); 강현정    (부산대학교 의학전문대학원 병리학교실   ); 김익두    (부산대학교 의학전문대학원 병리학교실   ); 설미영    (부산대학교 의학전문대학원 병리학교실   ); 최경운    (부산대학교 의학전문대학원 병리학교실  );
  • 초록

    The aim of this study was to evaluate the diagnostic value of fine needle aspiration cytology (FNAC) for the assessment of palpable enlarged lymph nodes. The authors reviewed the results of 1,346 FNACs of palpable enlarged lymph nodes performed at Pusan National University Hospital from 1998 to 2004. Of the 1,346 cases, 1,265 (94.0%) were satisfactory and 81 (6.0%) unsatisfactory. Cytologic diagnoses were judged in 488 cases, based on subsequent histologic diagnoses, clinical follow up, or both. Global results for all malignancies (lymphoid and non-lymphoid neoplasms) based on cases with final diagnoses, showed a sensitivity of 87.4% and a specificity of 98.7%. The overall diagnostic accuracy was 93,2%, and the false negative rate reduced from 12,6% to 7,3% when lymphomatous cases were excluded. The annual data for this period showed that the number of diagnostic lymph node biopsies and the rate of inadequately sampled material markedly decreased. Gene rearrangement studies for IgH and TCR ${\gamma}$ were helful in 30 cases. FNAC is a useful initial diagnostic procedure for the evaluation of palpable enlarged lymph nodes. However, the technique should be assisted by the appropriate ancillary studies and by proper interpretation by a cytopathologist.


  • 주제어

    Fine needle aspiration cytology .   Lymph node .   Palpable.  

  • 참고문헌 (22)

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    19. Thomas JO, Adeyi D, Amanguno H. Fine-needle aspiration in the management of peripheral lymphacienopathy in a developing country. Diagn Cytopathol 1999;21:159-62 
    20. Benhattar J, Delacretaz F, Martin P, Chaubert P, Costa J. Improved polymerase chain reaction detection of clonal T cell lymphoid neoplasms. Diagn Mol Pathol 1995;4:108-12 
    21. Stewart CJ, Duncan JA, Farquharson M, Richmond J. Fine needle aspiration cytology diagnosis of malignant lymphoma and reactive lymphoid hyperplasia. J Clin Pathol 1998;51:197-203 
    22. Kim CH. Fine needle aspiration cytology of lymph node - reactive hyperplasia vs malignant lymphoma. Korean J Cytopathol 2006;17:75-8     

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