본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Korean journal of pediatrics v.50 no.4, 2007년, pp.335 - 339   피인용횟수: 4

알레르기비염 및 부비동염과 천식의 연관성
Allergic rhinitis, sinusitis and asthma - evidence for respiratory system integration -

김현희   (가톨릭대학교 의과대학 소아과학교실  );
  • 초록

    The link between upper airway disease (allergic rhinitis and sinusitis) and lower airway disease (asthma) has long been of interest to physicians. Many epidemiological and pharmacological studies have provided a better understanding of pathophysiologic interrelationship between allergic rhinitis and asthma. The vast majority of patients with asthma have allergic rhinitis, and rhinitis is a major independent risk factor for asthma in cross-sectional and longitudinal studies. The association between sinusitis and asthma has long been appreciated. Through the recent evidences, allergic rhinitis, sinusitis, and asthma may not be considered as different diseases but rather as the expression in different parts of the respiratory tract of same pathological process in nature. Various mechanisms have been proposed to explain the relationship between asthma and upper airway diseases, but the underlying mechanisms are not completely discovered. The implications for the one-airway hypothesis are important not only academically but also clinically for diagnostic and therapeutic purposes.


  • 주제어

    Allergic rhinitis .   Sinusitis .   Asthma.  

  • 참고문헌 (30)

    1. Kapsali T, Horowitz E, Diemer F, Togias A. Rhinitis is ubiquitous in allergic asthmatics. J Allergy Clin Immunol 1997;99:S138 
    2. Leynaert B, Neukvich F, Demoly P, Bousquet J. Epidemiologic evidence for asthma and rhinitis comorbidity. J Allergy Clin Immunol 2000;106:S201-5 
    3. Ozcan M, Ortaponuk H, Naldoken S. Pulmonary aspiration of nasal secretions in patients with chronic sinusitis and asthma. Arch Otolaryngol Head Neck Surg 2003;129:1006-9 
    4. Crystal-Peters J, Neslusan C, Crown WH, Torres A. Treating allergic rhinitis in patients with comorbid asthma: The risk of asthma-related hospitalizations and emergency department visits. J Allergy Clin Immunol 2002;109:57-62 
    5. Friedman R, Ackerman M, Wald E. Athma and bacterial sinusitis in children. J Allergy Clin Immunol 1984;74:185-94 
    6. Ikeda K, Tanno N, Tomura G. Endoscopic sinus surgery improves pulmonary function in patients with asthma associated with chronic sinusitis. Ann Otol Rhinol Laryngol 1999;108:355-9 
    7. Grossman J. One airway, one disease. Chest 1997;11:11S-16S 
    8. Simons FER. Allergic rhinobronchitis: The asthma-allergic rhinitis link. J Allergy Clin Immunol 1999;104:534-40 
    9. Welsh PW, Stricker WE, Chu CP. Efficacy of beclomethasone nasal solution, flunisolide and cromolyn in relieving symptoms of ragweed allergy. Mayo Clin Proc 1987;62:125-34 
    10. Palmer JN, Conley DB, Dong RG. Efficacy of endoscopic sinus surgery in the management of patients with asthma and chronic sinusitis. Am J Rhinol 2001;15:49-53 
    11. Smith JM. Epidemiology and natural history of asthma, allergic rhinitis, and atopic dermatitis (eczema), Middleton E Jr, Reed CE, Ellis EF, Adkinson NF Jr, Yunginger JW, editors. Allergy Principles and Practice. St Louis, CV Mosby, 1988; 891-929 
    12. Borish L. Sinusitis and asthma: entering realm of evidencebased medicine. J Allergy Clin Immunol 2002;109:606-8 
    13. Denburg JA, Sehmi R, Saito H. Systemic aspects of allergic disease: bone marrow response. J Allergy Clin Immunol 2000;106:S242-6 
    14. Kay AB. Concepts of allergy and hypersensitivity. In Kay AB, ed. Allergy and Allergic Disease. Oxford, UK: Blackwell Science Ltd., 1997:23-35 
    15. Adams RJ, Fuhlbrigge AL, Finkelstein JA, Weiss S. Intranasal steroids and the risk of emergency department visits for asthma. J Allergy Clin Immunol 2002;109:636-42 
    16. ten Brinke A, Grootendorst DC, Schmidt JT. Chronic sinusitis in severe asthma is related to spectrum eosinophilia. J Allergy Clin Immunol 2002;109:621-6 
    17. Togia AG. Systemic immunologic and inflammatory aspects of allergic rhinitis. J Allergy Clin Immunol 2000;106:S247-50 
    18. ISAAC Steering committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 1998;351:1225-332 
    19. Rschelofsky G, Katz RM, Siegel SC. Chronic sinus disease with associated reactive airway disease in children. Pediatrics 1984;73:526-9 
    20. Devalia JL, Bayram H, Ruszna C. Mechanism of pollutioninduced airway disease: in vitro studies in the upper and lower airways. Allergy 1997;52:45-51 
    21. Jarjour NN, Gern JE, Kelly EA, Swenson CA, Dick CR, Busse WW. The effect of an experimental rhinoirus 16 infection on bronchial lavage neutrophils. J Allergy Clin Immunol 2000;105:1169-77 
    22. Kaufman J, Wright GW. The effect of nasal and nasopharyngeal irritation on airway resistance in man. Am Rev Respir Dis 1969;100:626-30 
    23. Bucca C, Rolla J, Brussino L. Are asthma-like symptoms due to bronchial or extrathoracic airway dysfunction? Lancet 1995;346:791-5 
    24. Bresciani M, Paradis L, DesRoches A. Rhinosinusitis in severe asthma. J Allergy Clin Immunol 2001;107:73-80 
    25. Settipane RJ, Hagy GW, Settipane GA. Long-term risk factors for developing asthma and allergic rhinitis: a 23- year follow-up study of college students. Allergy Proc 1994;15:21-5 
    26. Ramsdale EH, Morris MM, Roberts RS, Hargreave FE. Asymptomatic bronchial hyperresponsiveness in rhinitis. J Allergy Clin Immunol 1985;75:573-7 
    27. Denburg J, Sehmi R, Saito H, Jeong PS, Inman MD, O'byrne PM. Systemic aspects of allergic disease: Bone marrow response. J Allergy Clin Immunol 2000;106:S242-6 
    28. Moller C, Dreborg S, Ferdousi HA, Halken S, Host A, Jacobson L et al. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis( the PAT-Study). J Allergy Clin Immunol 2002;109:251-6 
    29. Greisner WA III, Settipane RJ, Settipane GA. Co-existence of asthma and allergic rhinitis: A 23-year follow-up study of college students. Allergy Asthma Proc 1998;19:185-8 
    30. Griffin MP, McFadden ER, Ingram RH. Airway cooling in asthmatic and nonasthmatic subjects during nasal and oral breathing. J Allergy Clin Immunol 1982;69:354-9 
  • 이 논문을 인용한 문헌 (4)

    1. Jung, Jin-Ki ; Jung, Hye-Mi ; Seo, Woon-Gyo ; Park, Yong-Ki 2010. "Anti-allergic effect of Osterici Radix water extract in human mast cells" 大韓本草學會誌 = The Korea journal of herbology, 25(3): 35~41     
    2. Kang, Seok-Yong ; Hong, Seung-Ug ; Park, Yong-Ki 2012. "Effects of KOB, a polyherbal medicine for allergic rhinitis and its main herb, Astragali Radix on allergic responses in OVA-induced Allergic rhinitis mice" 大韓本草學會誌 = The Korea journal of herbology, 27(4): 1~7     
    3. Jung, Jin-Ki ; Park, Yong-Ki 2012. "Effects of Saposhnikoviae Radix on allergic responses in OVA-induced Allergic rhinitis mice" 大韓本草學會誌 = The Korea journal of herbology, 27(5): 85~91     
    4. Ha, Hyocheol ; Oh, Sarang ; Lee, Jihye ; Jung, Ji Wook 2014. "The Study of Cytokine Inhibitory Effect using Careswell" 大韓本草學會誌 = The Korea journal of herbology, 29(3): 79~85     

 저자의 다른 논문

  • 김현희 (20)

    1. 2001 "불명열로 오인된 아급성 괴사성 림프선염 1례" 소아감염 = Korean journal of pediatric infectious diseases 8 (2): 253~259    
    2. 2002 "선천성 단발성 간농양 1례" 소아과 = Journal of the Korean pediatric society 45 (11): 1426~1429    
    3. 2002 "질자궁수종 신생아 2례" 소아과 = Journal of the Korean pediatric society 45 (2): 278~283    
    4. 2003 "가와사키병 환아의 혈장내 G-CSF와 GM-CSF 농도 및 과립구에서의 이들 수용체의 발현 변화" 소아과 = Journal of the Korean pediatric society 46 (4): 376~381    
    5. 2003 "알레르기 염증 기전에서 호염기구의 역할" 소아과 = Journal of the Korean pediatric society 46 (6): 528~535    
    6. 2003 "백혈구 증가증 환아의 혈장내 G-CSF와 GM-CSF의 농도 및 과립구에서의 이들 수용체의 발현" 소아과 = Journal of the Korean pediatric society 46 (3): 271~276    
    7. 2005 "Young-Simpson 증후군 증례" Korean journal of pediatrics 48 (9): 1016~1018    
    8. 2005 "A Case of Glanzmann's Thrombasthenia with β3 Subunit Missense Mutation" 대한유전성대사질환학회지 = Journal of the Korean Society of Inherited Metabolic Disease 5 (1): 126~132    
    9. 2008 "비특이 반응성 간염에서 AST와 ALT 수치 상승과 회복" Korean journal of pediatrics 51 (4): 396~400    
    10. 2014 "신생아에서 혈뇨와 폐렴이 동반된 선천 매독 1례" 소아감염 = Korean journal of pediatric infectious diseases 21 (1): 65~70    

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
유료다운로드
  • 원문이 없습니다.

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기