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Journal of bacteriology and virology : JBV v.37 no.3, 2007년, pp.169 - 175   피인용횟수: 2

대전지역 설사환자 분변 유래 Group A Rotavirus의 P 및 G 유전자형 분포
Epidemiological Surveillance of P and G Genotypes of Group A Rotavirus Detected from Diarrheic Patients in Daejeon Region

박선경    (대전광역시보건환경연구원   ); 허영선    (대전광역시보건환경연구원   ); 빙선혜    (대전광역시보건환경연구원   ); 천두성    (질병관리본부   ); 초가기    (충남대학교 수의과대학   ); 전무형    (충남대학교 수의과대학  );
  • 초록

    During 3 years surveillance (January 2001 through December 2003) for acute gastroenteritis in human in Daejeon region, 432 out of 4,869 stool samples were selected as rotavirus-positive specimens by means of antigen-capture enzyme-linked immunosorbent assay (ELISA). The P (VP4) and G (VP7) genotypes for 432 stool samples were investigated by reverse transcription polymerase chain reaction (RT-PCR) and nested multiplex PCR. The most prevalent P subtype was P[8] (44.9%), followed by P[4] (25.7%) and P[6] (17.1%). No cases for P[10] and P[9] subtypes were found through the study. In G subtyping, G1 (53.2%) was the most frequently found G type, followed by G2 (23.1 %), G3 (9.5%), G4 (6.7%), and G9 (0.9%). The order of detection rates for G2, G3 and G4 was variable by years. The most common G- and P- type combination found in this study was G1P[8] (33.1%), followed by G2P[4] (20.4%), G1P[6] (10.0%), G3P[8] (7.2%) and G4P[6] (4.2%). The mixed types of G and P were observed most frequently in P[8] (1.4%) and G1 (3.2%), respectively. This is the first molecular epidemiological study for Group A rotavirus in Daejeon region. The results might be useful data for evaluating the epidemiological status of rotaviral diarrhea in the region.


  • 주제어

    Rotavirus .   Acute gastroenteritis .   P and G genotypes .   Nested multiplex PCR.  

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  • 이 논문을 인용한 문헌 (2)

    1. Lee, Kang-Bum ; Kim, Jin-Won ; Lee, Sun-Wha ; Cheon, Doo-Sung ; Jee, Young-Mee ; Kang, Shien-Young 2007. "Isolation and Characterization of G9 Human Rotaviruses" Journal of bacteriology and virology : JBV, 37(4): 231~240     
    2. 2009. "" Journal of bacteriology and virology : JBV, 39(1): 21~28     

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