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제주 손바닥 선인장의 초음파 추출을 통한 면역활성 증진
Enhancement of Immune Activities of Opuntia ficus-indica L. Miller by Ultrasonification Extraction Process

권민철   (강원대학교 BT특성화학부(대학)UU0000037  ); 한재건   (강원대학교 BT특성화학부(대학)UU0000037  ); 정향숙   (강원대학교 BT특성화학부(대학)UU0000037  ); Qadir, Syed Abdul    (강원대학교 BT특성화학부(대학)   ); 최영범   (정우식품CC0039714  ); 고정림   (정우식품CC0039714  ); 임태일   (태림상사(주)CC0017634  ); 이현용   (강원대학교 생명공학연구소UU0000037  );
  • 초록

    Immune activities of Opuntia ficus indica L. Miller were investigated through aqueous extracts associated with ultrasonification process at $60^{\circ}C$ , and showed the highest promotion of human B and T cell growth, up to 52% and 41%, respectively, compared to the control. The secretion of TNF- ${\alpha}$ and IL-60 was also enhanced by the addition $(0.5mg/m{\ell})$ of the extracts, up to 48%. NK cell activation was significantly improved up to 1.3 times higher than the case of adding other extracts. It was also found that extracts from O. ficus indica could yield higher nitric oxide production from macrophage than Lipopolysaccaharides (LPS). It can be concluded that, in general, the extracts treated with ultrasonification has higher Immune acitivities than others, possibly by higher yielding immune-modulatory than conventional extraction process. The optimum condition for the extraction of O. ficus-indicais water extraction associated with ultrasonification.


  • 주제어

    Opuntia ficus indica L.   Miller .   Immune Activity .   Ultrasonification.  

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  • 이 논문을 인용한 문헌 (5)

    1. Jeong, Myoung-Hoon ; Ha, Ji-Hye ; Oh, Sung-Ho ; Kim, Seung-Seop ; Jin, Ling ; Lee, Hak-Ju ; Kang, Ha-Young ; Prak, Uk-Yeon ; Lee, Hyeon-Yong 2009. "Improvement of Biological activities of Acer mono and Acer okamotoanum Saps by Nano-encapsulation Process" 韓國林學會誌 = Journal of Korean Forest Society, 98(4): 399~408     
    2. Choi, Jae-Eul ; Li, Xiangguo ; Han, Young-Hwan ; Lee, Ki-Teak 2009. "Changes of Saponin Contents of Leaves, Stems and Flower-buds of Panax ginseng C. A. Meyer by Harvesting Days" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 17(4): 251~256     
    3. Ha, Ji-Hye ; Kwon, Min-Chul ; Kim, Seung-Seop ; Jeong, Myoung-Hoon ; Hwang, Baik ; Lee, Hyeon-Yong 2010. "Enhancement of Skin-Whitening and UV-Protective Effects of Centella asiatica L. Urban by Utrasonification Process" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 18(2): 79~85     
    4. Park, Si-Hyang ; Choung, Se-Young ; Choi, Yeung-Joon 2011. "Immune Regulating Effect of Polysaccharide Fraction from Sea Hare (Aplysia kurodai)" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 40(3): 372~378     
    5. Jeong, Yun Sook ; Lee, Sang Hoon ; Song, Jin ; Hwang, Kyung-A ; Noh, Geon Min ; Jang, Da Eun ; Hwang, In Guk 2016. "Phytochemical Contents and Antioxidant Activities of Opuntia ficus-indica var. saboten" 한국식품영양학회지 = The Korean journal of food and nutrition, 29(5): 767~776     

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  • 한재건 (5)

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