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생약학회지 v.40 no.4 = no.159, 2009년, pp.376 - 381  

상추 7 품종의 Quinic Acid 유도체 분석 및 Peroxynitrite 소거효과
Analysis of Quinic Acid Derivatives on Seven Cultivars of the Lettuce (Lactuca sativa L.) and Peroxynitrite Scavenging Effect

누그로호 아궁    (상지대학교 제약공학과   ); 장석우    (농촌진흥청 고령지농업연구센터   ); 김원배    (농촌진흥청 고령지농업연구센터   ); 이강노    (성균관대학교 약학대학   ); 최재수    (부경대학교 식품생명공학부   ); 박희준    (상지대학교 제약공학과  );
  • 초록

    The compositional analysis and the peroxynitrite ( $ONOO^-$ ) scavenging assay were undertaken to demonstrate beneficial dietary effect of lettuce (Lactuca sativa L., Compositae). Quinic acid derivatives of the seven cultivars were qualitatively and quantitatively analyzed by HPLC to lead to the finding of 3,4-di-O-caffeoyquinic acid and 3-O-p-coumaroylquinic acid and their contents ranged over 2.72-4.47 mg/g and 8.97-23.26 mg/g, respectively. A cultivar Hacheong had the highest quantity of quinic acid derivatives. The peroxynitrite scavenging effect of the five cultivars (Jangsu, Gosina 27, Gopung, Yeolpungjeogchima, and Mipungjeogchugmyeon) were ranged over 7.45-8.26 ${\mu}g$ /ml as $IC_{50}s$ while those of Hacheong and Mihong had less effect ( $IC_{50}$ >10 ${\mu}g$ /ml).

  • 주제어

    Lactuca sativa .   Compositae .   peroxynitrite .   quinic acid .   HPLC.  

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