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폐쇄성과 비폐쇄성 무정자증 환자에서 신선고환조직 정자와 동결고환조직 정자를 이용한 배발달률과 임신율의 비교 결과
Comparative Results of Embryo Development and Clinical Pregnancy using Sperm Retrieved from Fresh and Frozen-thawed Testicular Tissue from Patients with Obstructive and Non-obstructive Azoospermia

박용석    (관동대학교 의과대학 제일병원 생식생물학 및 불임연구실   ); 최수진    (관동대학교 의과대학 제일병원 생식생물학 및 불임연구실   ); 이선희    (관동대학교 의과대학 제일병원 생식생물학 및 불임연구실   ); 박동욱    (관동대학교 의과대학 제일병원 생식생물학 및 불임연구실   ); 임천규    (관동대학교 의과대학 제일병원 생식생물학 및 불임연구실   ); 전진현    (관동대학교 의과대학 제일병원 생식생물학 및 불임연구실   ); 궁미경    (관동대학교 산부인과   ); 박찬우    (관동대학교 산부인과   ); 송인옥    (관동대학교 산부인과   ); 서주태    (관동대학교 비뇨기과  );
  • 초록

    목 적: 폐쇄성과 비폐쇄성 무정자증 환자에서 신선고환조직 정자와 융해고환조직 정자를 이용한 배발달과 임신결과를 비교 분석하였다. 연구방법: 폐쇄성과 비폐쇄성 무정자증 환자에서 총 222 주기의 TESE-ICSI를 시행하였다. 정자는 신선 또는 융해 고환조직으로부터 회수하였다. 수정은 ICSI 후 16~18시간째 확인하였으며, 배발달률과 임신율을 분석하였다. 결 과: 폐쇄성 무정자증군과 비폐쇄성 무정자증군에서 수정률은 유의하게 차이가 났으나 (75.2% 대 56.7%, p


    Objective: To compare the embryonic development and pregnancy results using sperms retrieved from fresh and frozen-thawed testicular tissue in patients with obstructive (OA) and non-obstructive azoospermia (NOA). Methods: A total two hundred twenty-two cycles of TESE-ICSI were performed in OA and NOA. Sperms were retrieved from fresh and frozen-thawed testicular tissue. ICSI was performed patient's own sperm. Fertilization was assessed 16~18 hrs after ICSI. Embryo development and pregnancy rates were analysed. Results: The fertilization rates were significantly different between OA and NOA patients (75.2% vs. 56.7%, p


  • 주제어

    폐쇄성 무정자증 .   비폐쇄성 무정자증 .   동결보존 .   고환정자 .   배발달.  

  • 참고문헌 (43)

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  • 이 논문을 인용한 문헌 (2)

    1. 2011. "" Clinical and experimental reproductive medicine : CERM, 38(3): 142~147     
    2. 2016. "" Clinical and experimental reproductive medicine : CERM, 43(4): 221~227     

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