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분화 갑상선암의 수술 및 예후에 대한 고찰
Surgery and Prognostic Consideration in Differentiated Thyroid Cancer(DTC)

변경도    (인제대학교 의과대학 부산백병원 외과학교실   ); 하태권    (인제대학교 의과대학 부산백병원 외과학교실   ); 유성목    (인제대학교 의과대학 부산백병원 외과학교실   ); 김태현    (인제대학교 의과대학 부산백병원 외과학교실   ); 김상효    (인제대학교 의과대학 부산백병원 외과학교실  );
  • 초록

    Purpose : For the past 10 years, the incidence of thyroid cancer has been rapidly increased in female population showing current incidence of 12,000 new thyroid cancer patients annually in Korea. Though differentiated thyroid cancer is known to show favorable prognosis and excellent long-term survival from slow growth and late distant metastasis, we re-evaluated prognostic factors of recurrence and mortality following surgical procedures based on our cases. Material and Methods : 954 Patients of DTC surgically treated at Department of Surgery, Inje University Busan Paik Hospital between 1980 and 2004 were reviewed in the aspects of the surgical procedures, clinical staging, risk factors, recurrence and their outcome through median follow-up period of 10.5 years. Results : Recurrence in remnant thyroid, cervical nodes, and distant metastasis were observed in 84 paients(8.8%), and 31 patients were confirmed to be died of locoregional recurrence of cancer and distant metasasis. Regarding the risk factors to recurrence, tumor size, extrathyroidal extension, nodal metastasis, and capsular invasion were significant predictors(p


  • 주제어

    분화 갑상선암 .   재발 .   생존율.  

  • 참고문헌 (25)

    1. Korea Central Cancer Registry. 2002 Annual Report of the korea central cancer Registry;2003 
    2. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun M. Cancer statistics, CA Cancer J Clin. 2007;57:43-66 
    3. Clark JR, Lai P, Hall F, Borglund A, Eski S, Freeman JL. Variables predicting distant metastases in thyroid cancer. Laryngoscope. 2005;115:661-667 
    4. Ashok R, Shaha MD. Implications of prognostic factors and risk groups in the management of differentiated thyroid cancer. Laryngoscope. 2004;114:393-402 
    5. Baudin E, Travagli JP, Ropers J, Mancusi F, Bruno-Bossio G, Gaillon B. Microcarcinoma of the thyroid gland: The Gustar Roussy Institute experience. Cancer. 1998;83:553-559 
    6. Shah JP, Loree TR, Dharker DD, Strong EW, Begg C, Vlamis V. Prognostic factors in differentiated carcinoma of the thyroid gland. Am J Surg. 1992;164:658 
    7. Sobin LH, Wittekind C. Head and Neck Tumors. In: TNM classification of malignant tumors, sixth edition. John Wiley & Sons, New York. 2002:52-56 
    8. Pellegriti G, Scolio C, Lumera G, Regalbuto C, Vigneri R. Clinical behavior and outcome of papillary thyroid cancers smaller than 1.5cm in diameter: Study of 299 cases. J Clin Endoclinol Metab. 2004;89:3713-3720 
    9. Hay ID, Grant CS, Varn Heerden JA, Goellner JR, Ebersold JR, Bergstralh EJ. Papillary thyroid microcarcinoma: A study of 535 cases observed in a 50-year period. Surgery. 1992;112:1130-1147 
    10. Machens A. Hinze R, Thomusch O, Dralle H. Pattern of modal metastasis for primary and reoperative thyroid cancer. World J Surg. 2002;26:22-28 
    11. Sherman SI. Thyroid carcinoma. Lancet. 2003;361:501-511 
    12. Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, et al. Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2006;16:109-142 
    13. Hay ID, Grant CS, Taylor WF, McConahy WM. Ipsilateral lobectomy versus bilateral lobar resection in papillary carcinoma: A retrospective analysis surgery of surgical outcome using a novel prognostic scoring system. Surgery. 1987;102:1088-1095 
    14. McConahey WM, Hay ID, Woolner LB, Van Heerden JA, Taylor WF. Papillary thyroid cancer treated at the Mayo Clinic, 1946 through 1970: Initial manefestations, pathologic findings, theraphy and outcome. Mayo clin proc. 1986;61:978-996 
    15. Haigh PI, Urbach DR, Rotstein LE. Extent of thyroidectomy is not a major determinant of survival in low-or high-risk papillary thyroid cancer. Ann Surg Oncol. 2005;12(1):81-89 
    16. Appetecchia M, Scarcello G, Pucci E, Procaccin A. Outcome after treatment of papillary thyroid microcarcinoma. J Exp Clin Cancer Res. 2002;21(2):159-164 
    17. Caron NR, Clark OH. Papillary thyroid cancer.surgical management of lymph node meatastasis. Curr Treat Options Oncol. 2005; 6:311-322 
    18. Martin JS, Schlumberger MJ. Papillary and follicular thyroid carcinoma. N Eng J Med. 1998;338:297-306 
    19. Chew MH, Chan G, Siddigui MMA, Tai BC, Sivanandan R, Soo LC, et al. Risk-Stratified Management of well-differentiated Thyroid cancers: A Review of Experience from a Single Institution, 1990-2003 World J Surg. 2008;32:386-394 
    20. Cady B, Rossi R. An expanded view of risk group definition in differentiated thyroid carcinoma. Surgery. 1988;104:947-953 
    21. Sosa Ja, Udelsman R. Total thyroidectomy for differentiated thyroid cancer. J Surg Oncol. 2006;94(8):701-707 
    22. Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States 1973-2002. JAMA. 2008;295:2164-2167 
    23. Sakorafas GH, Sampains D, Safioleas M. Cervical lymph node dissection in papillary thyroid cancer: Current trends, persisting controversies, and unclarified uncertainties. Surg Oncol, 2009: 1-14 
    24. DeGroot LJ, Kaplan EL, Mccormick M, Straus FH. Natural history, treatment, and course of papillary thyroid carcinoma. J Clin Endocrinol Metab. 1990;71:414-424 
    25. Pacini F, Schlumberger M, Dralle H, Elisei R, smit JW, Wiersinga W. European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. Eur J Endocrinol. 2006;154:787-803 

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