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GC/MS를 이용한 담배연기중 Melamine과 Cyanuric Acid 분석
Analysis of Melamine and Cyanuric Acid in Cigarette Mainstream Using GC/MS

곽호근    (충북대학교 농업생명환경대학 특용식물학과   ); 이수현    (충북대학교 농업생명환경대학 특용식물학과   ); 임흥빈    (충북대학교 농업생명환경대학 특용식물학과  );
  • 초록

    In this study, we investigated the existence of melamine and cyanuric acid in cigarette smoke because leaf tobacco contains lots of nitrogen compounds and they are capable of pyrolytic synthesis while smoking. The extraction and derivatization conditions of two compounds were performed according to the procedure of U.S. Food and Drug Administration(FDA). Ky3R4F as reference cigarette was smoked on ISO condition(Puff volumne : 35 ml, duration : 60 sec, Interval : 2 sec). Compared with the results Ky3R4F and standard solution, retention time of two compounds was not corresponded. As a result, we concluded that melamine and cyanuric acid were not existed in cigarette smoke.


  • 주제어

    melamine .   cyanuric acid .   cigarette smoke.  

  • 참고문헌 (23)

    1. Puschner, B., Poppenga, R. H., Lowenstine, L. J., Filigenzi, M. S. and Pesavento, P. A.(2007) Assessment of melamine and cyanuric acid toxicity in cats. J. Vet. Diagn. Invest. 19:616-624 
    2. Guan, N., Fan, Q., Ding, J., Zhao, Y., Lu, J., Ai, Y., Xu, G., Zhu, S., Yao, C., Jiagn, L., Miao, J., Zhang, H., Zhao, D., Liu, X. and Yao, Y. (2009) Melamine-contaminated powdered formula and urolithiasis in young children. N. Engl. J. Med. 360:1067-1074 
    3. WHO.(2009) Toxicological and health aspects of melamine and cyanuric acid:Report of a WHO Expert Meeting in collaboration with FAO supported by Health Canada 
    4. Yokley, R. A., Mayer, L. C., Ruhi Rezaaiyan., Manuli, M. E. and Cheung, M. W. (2000) Analytical method for the determination of cyromazine and melamine residues in soil using LC-UV and GC-MSD. J. Agric. Food Chem. 48:3352-3358 
    5. U. S. Food and Drug Administration.(2009) GC-MS Screen for the presence of melamine, ammeline, ammelide and cyanuric acid 
    6. Li, J., Qi, H. Y. and Shi, Y. P.(2009) Determination of melamine residues in milk products by zirconia hollow fiber sorptive microextraction and gas chromatographymass spectrometry. Journal of Chromatography A. 1216:5467-5471 
    7. Agilent Technologies.(2009) Rapid screening and confirmation of melamine and its analogs in baby formula and soy products using triple quadrupole GC/MS and Backflushing 
    8. Filigenzi, M. S., Puschner, B., Aston, L. S. and Poppenga, R. H.(2008) Diagnostic determination of melamine and related compounds in kidney tissue by liquid chromatography/tandem mass spectrometry. J. Agric. Food Chem. 56:7593-7599 
    9. Yan, N., Zhou, L., Zhu, Z. and Chen, X.(2009) Determnation of melamine in dairy products, fish feed, and fish by Capillary zone elecrtophoresis with diode array detection. J. Agric. Food Chem. 57:807-811 
    10. Dobson, R. L. M., Motlagh, S., Quijano, M., Thomas Cambron, R., Baker, T. R., Pulllen, A. M., Regg, B. T., Bigalow-Kern, A. S., Vennard, T., Fix, A., Reimschuessel, R., Overmann, G., Shan, Y. and Daston, G. P(2008) Identification and characterization of toxicity of contaminants in pet food leading to an outbreak of renal toxicity in cats and dogs. Toxicological sciences. 106:251-262 
    11. Pukkila, J., Peltonen, K. and Savolainen, T.(1987) Determination of melamine in air by high-performance liquid chromatography with ultraviolet detection. Journal of Chromatography A. 411:409-414 
    12. Doull, J., Frawley, J. P., George, W.(1994) List of ingredients added to tobacco in the manufacture of cigarettes by six major American cigarette companies. Tobacco Journal International. 196:32-39 
    13. Perdigao, L. M. A., Champness, N. R. and Benton, P. H.(2006) Surface self-assembly of the cyanuric acid-melamine hydrogen bonded network. Chem. Commun. 5:538-540 
    14. Johes, K. and Patel, K.(2007) Analytical method for the quantitative determination of cyanuric acid as the degradation product of sodium dichloroisocyanurate in urine by liqid chromatography mass spectrometry. Journal od Chromatography B. 853:360-363 
    15. Cantu, R., Evans, O., Kawahara, F. K., Shoemaker, J. A. and Dufour, A. P.(2000) An HPLC method with UV detection, pH control, and Reductive ascorbic acid for cyanuric acid analysis in water. Anal. Chem. 72:5820-5828 
    16. Andersen, W. C., Turnipseed, S. B., Karbiwnyk, C. M., Clack, S. B., Madson, M. R., Gieseker, C. M., Miller, R. A., Rummel, N. G. and Reimschuessel, R. (2008) Determination and confirmation of melamine residues in catfish, trout, tilapoa, salmon, and shrimp by liquid chromatography with tandem mass spectrometry. J. Agric. Food Chem. 56:4340-4347 
    17. Thompson, M. E., Lewin-smith, M. R., Kalasinsky, V. F., Pizzolato, K. M., Fleetwood, M. L., Mcelhaney, M. R. and Johnson, T. O.(2008) Characterization of melamine-containing and Calcium oxalate crystals in three Dogs with suspected pet food-induced nephrotoxicosis. Vet. Pathol. 45:417-426 
    18. Ehling, S., Tefera, S. and Ho. I. P.(2007) Highperformance liquid chromatographic method for the simultaneous detection of the adulteration of cereal flours with melamine and related triazine by-products ammeline, ammelide, and cyanuric acid. Food Additives and Contamination. 24:1319-1325 
    19. Reimschuessel, R., Gieseker, C. M., Miller, R. A., Ward, J., Boehmer, J., Rummel, N., Heller, D. N., Nochetto, C., Hemakanthi de Alwis, G. K., Bataller, N., Aendersen, W. C., Turnipseed, S. B., Karbiwnyk, C. M., Satzger, R. D., Crowe, J. B., Wilder, N. R., Reinhard, M. K., Roberts, J. F.and Witkowski, M. R.(2008) Evaluation of the renal effects of experimental feeding of melamine and cyanuric aicd to fish and pigs. American Journal of Veterinary Research. 69:1217-1228 
    20. He, L., Liu, Y., Lin, M., Awika, J., Ledoux, D. R., Li, H. and Mustapha, A.(2008) A new approch to measure melamine, cyanuric acid and melamine cynurate using surfase enhanced raman spectroscopy coupled with gold nanosubstrates. Sens. & Instrumen. Food Qual. 2:66-71 
    21. Agilent Technologies.(2008) Trace-level analysis of melamine in milk products on agilent 7890A/5975C GC/MSD using a New agilent J&W DB-5ms ultra inert column and sampliq SCX cartridges 
    22. Eric A. E. Garber.(2008) Detection of melamine using commercial enzyme-linked immunosorbent assay technology. Journal of Food Protection. 71:590-594 
    23. Dube, M. F. and C. R. Green.(1982) Methods of collection of smoke for analytical purposes. Rec. Advanc. Tob. Sci. 8:42-102 

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