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오매 에탄올 추출물의 항산화 활성 및 항암 활성 연구
Study on Antioxidant and Cytotoxic Activities in Ethanol Extract from Prunus mume

전연희   (경북대학교 식품영양학과UU0000096  ); 권지은   (경북대학교 식품영양학과UU0000096  ); 김미라   (경북대학교 식품영양학과, 장수생활과학연구소UU0000096  );
  • 초록

    Prunus mume is well known contain many functional materials that play beneficial roles in the human body. Studies have found that many organic acids and polyphenol compounds exist in Prunus mume. In this study, content of total polyphenols and flavonoids, antioxidative activity and cytotoxicity of ethanol extract from Prunus mume were measured Contents of total polyphenolic and total flavonoid compounds in ethanol extract from Prunus mume were 16.92 mg/g and 59.95 mg/g, respectively. The $IC_{50}$ of ethanol extract from Prunus mume were $237.72 {\mu}g$ /assay and $239.58 {\mu}g$ /assay by DPPH and ABTS radical cation scavenging test, respectively. Additionally, ferric ion reducing antioxidant power (FRAP) value of ethanol extract from Prunus mume was 0.94 mM ( $FeSO_4$ eq.) by $800 {\mu}g$ /assay. Cytotoxicity of Prunus mume against five kinds of cancer cell lines increased as the extract concentration increased Especially, cytotoxicity of the ethanol extract against A-549 (lung cancer line) was higher than that against any other cancer cell line by both MTT and SRB assay. These results show that ethanol extract of Prunus mume has considerably high antioxidative and cytotoxic activities.


  • 주제어

    Prunus mume .   antioxidative activity .   cytotoxic activity.  

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  • 이 논문을 인용한 문헌 (3)

    1. Bae, Yu-Kyung ; Choe, Tae-Boo 2011. "Antioxidant and Cell Activity Using Extracts of Mume Fructus" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 19(5): 388~394     
    2. Kim, Won Baek ; Park, So Hae ; Hwang, Hye Sun ; Woo, Jung Yoon ; Lee, Hye Ryun ; Hwang, Dae Youn ; Choi, Ji Hye ; Lee, Heeseob 2012. "Antioxidative Activities and Whitening Effects of Solvent Fraction from Prunus davidiana (Carriere) Franch. Fruit" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 41(10): 1363~1370     
    3. Rho, Kyu-A ; Kim, Gyeong-Ji ; Ji, Hyun-A ; Lim, Han-Sol ; Chung, Kang-Hyun ; Lee, Kwon-Jai ; Song, Byeong Chun ; An, Jeung Hee 2015. "Antitumor and Free Radical-Scavenging Activities of Various Extract Fractions of Fruits and Leaves from Prunus mume" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 44(8): 1137~1143     

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