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Journal of microbiology and biotechnology v.20 no.6, 2010년, pp.985 - 987   SCIE 피인용횟수: 2
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Biotransformation of Bioactive (-)-Mellein by a Marine Isolate of Bacterium Stappia sp.

Feng, Zhile    (Department of Chemistry, Pukyong National University   ); Nenkep, Viviane N.    (Department of Chemistry, Pukyong National University   ); Yun, Keum-Ja    (Department of Chemistry, Pukyong National University   ); Zhang, Dahai    (Department of Chemistry, Pukyong National University   ); Choi, Hong-Dae    (Department of Chemistry, Dongeui University   ); Kang, Jung-Sook    (College of Dentistry, Pusan National University   ); Son, Byeng-Wha    (Department of Chemistry, Pukyong National University  );
  • 초록

    The biological transformation of the bioactive dihydroisocoumarin, (-)-mellein, isolated from the marinederived fungus Cladosporium sp., was studied. The preparativescale culture of (-)-mellein with a marine isolate of a bacterium Stappia sp. resulted in the isolation of its oxidized metabolite, (3R,4S)-4-hydroxymellein. The stereostructure of the metabolite obtained was assigned on the basis of detailed physicochemical data analyses.


  • 주제어

    Biotransformation .   dihydroisocoumarin .   (-)-mellein .   (3R,4S)-4-hydroxymellein .   Stappia sp.  

  • 참고문헌 (13)

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    7. Li, X., S. M. Lee, H. D. Choi, J. S. Kang, and B. W. Son. 2003. Microbial transformation of terreusinone, an ultraviolet-A (UV-A) protecting dipyrroloquinone, by Streptomyces sp. Chem. Pharm. Bull. 51: 1458-1459. 
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    12. Yang, G., V. N. Nenkep, X. N. Siwe, A. S. Leutou, Z. Feng, D. Zhang, H. D. Choi, J. S. Kang, and B. W. Son. 2009. An acetophenone derivative, clavatol, and a benzodiazepine alkaloid, circumdatin A, from the marine-derived fungus Cladosporium. Nat. Prod. Sci. 15: 130-133.     
    13. Leutou, A. S., G. Yang, V. N. Nenkep, X. N. Siwe, Z. Feng, T. T. Khong, H. D. Choi, J. S. Kang, and B. W. Son. 2009. Microbial transformation of a monoterpene, geraniol, by the marine-derived fungus Hypocrea sp. J. Microbiol. Biotechnol. 19: 1150-1152.     
  • 이 논문을 인용한 문헌 (2)

    1. 2014. "" Bulletin of the Korean Chemical Society, 35(9): 2870~2872     
    2. 2016. "" Natural product sciences, 22(3): 216~219     

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