본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

International journal of oral biology : official journal of the Korean Academy of Oral Biology and the UCLA Dental Research Institute v.35 no.1, 2010년, pp.7 - 12   피인용횟수: 2
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Monitoring of Methicillin-resistant Staphylococcus aureus in Nasal Swabs Obtained from Dental Clinic Healthcare Providers and Medical Environment Nurses

Han, Seung-Ho    (Department of Laboratory Medicine, Veterans Hospital   ); Song, In-Sook    (Department of Laboratory Medicine, Veterans Hospital   ); Kim, Jong-Koan    (Department of Laboratory Medicine, Veterans Hospital   ); Park, Jum-Gi    (Department of Laboratory Medicine, Veterans Hospital   ); Park, Jang-Hwan    (Department of Laboratory Medicine, Veterans Hospital   ); Lee, Myeong-Jae    (Department of Laboratory Medicine, Veterans Hospital   ); Kim, Shin-Moo    (Department Clinical Laboratory Science, Wonkwang Health Science College   ); Kim, Kang-Ju    (Department of Oral Microbiology, School of Dentistry, Wonkwang University  );
  • 초록

    The aims of this study were to investigate the nosocomial infection route of methicillin-resistant Staphylococcus aureus (MRSA) and explore preventative methods for this pathogen that involve blocking its dispersion. We cultured MRSA from nasal cavity swabs collected between June and July 2008 that we obtained from eight dental healthcare providers, 32 nurses and the sputum specimens of two patients from our hospital. In addition, we used VITEK 2 equipment to measure drug sensitivity, and we further performed biochemical testing and pulse-field gel electrophoresis (PFGE) to isolate MRSA colonies. The incidence of these bacteria on the nasal swabs was 25.0% from dental clinic healthcare providers, 13.6% from the internal medicine ward nurses and 30.0% from intensive care unit nurses. Moreover, MRSA was detectable in sputum specimens of ward patients. The antimicrobial agents resistance and partial PFGE types of MRSA showed a similar pattern. We suggest from these analyses that nasal cavity infection by MRSA could occur by cross contamination between healthcare providers and patients which underscores the importance of stringent MRSA management practices.


  • 주제어

    MRSA .   nosocomial infection .   nasal swab.  

  • 참고문헌 (22)

    1. Boerlin P, Kuhnert P, Hussy D, Schaellibaum M. Methods for entification of Staphylococcus aureus isolates in cases of bovine mastitis. J Clin Microbiol. 2003;41:767-771. 
    2. Boutiba-Ben Boubaker I, Ben Abbes R, Ben Abdallah H, Mamlouk K, Mamlouk K, Mahjoubi F, Kammoun A, Hammami A, Ben Redjeb S. Evaluation of a cefoxitin disk diffusion test for the routine detection of methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect. 2004;10:762- 765. 
    3. Chapin K, Musgnug M. Evaluation of three rapid method for the direct identification of Staphylococcus aureus from positive blood cultures J Clin Microbiol. 2003;41:4324-4327. 
    4. Cookson B. Is it time to stop searching for MRSA ? Screening is still important. J Brit Med. 1997;314:664-665. 
    5. Etiene J, Fleurette J, Ninet JF, Favet P, Gruer LD. Staphylococcus endocarditis after dental extraction. Lancet. 1986;2:511-512. 
    6. Etiene J, Brun Y, Fleurette J. Staphylococcus lugdunensis endocarditis. J Clin Pathol. 1989;42:892-893. 
    7. Franklin SR. The hospital environment a crossroads for infection. Arch Envirron Health. 1970;21:678-689. 
    8. Frebourg NB, Nouet D, Lemee L, Martin E, Lemeland JF. Comparion of ATB Staph, rapid ATB Staph, Vitek and E-test method for detection of oxacillin heteroresistance in staphylococci possesing mecA. J Clin Microbiol. 1998;36: 52-57. 
    9. Frency J, Brun Y, Bes M, Meugnier H, Grimont F, Grimon PAD, Newi C, Fleurette J. Staphylococcus lugdunensis sp. and Staphylococcus schleiferi sp. novel two species from human clinical specimens. Int Syst Bacteriol. 1998;38:168- 172. 
    10. Holliday MG, Ford M, Perry JD, Gould FK. Rapid identification of of Staphylococcus aureus by using fluorescent staphylocoagulase assays. J Clin Microbiol. 1999;37:1190- 1192. 
    11. Hemming VG, Overall JC JR, Britt MR. Nosocomial infections in a newbone intensive-care unit. N Engl J Med. 1976;294:1310-1315 
    12. Jeong HJ, Kim WJ, Kim MJ, Park SC. Nosocomial infection surveillance in the intensive care unit. Kor J Infect Dis. 1995;27:105-117. 
    13. Jeven MP, Coe AW, Praker MT. Methicillin resistance in Staphylococcus. Lancet. 1963;1:904-904. 
    14. Kim JS, Kim EC, Ki CS, Lee NY. Nosocomial outbreak of methicillin-resistant Staphylococcus aureus analyzed by molecular epidemiology. 1996;1:63-72. 
    15. Kim SJ. Plasmid profiles and ribotyping of methicillin-resistant Staphylococcus aureus. Department of Clinical Pathology. Graduate School. College of Medicine, Seoul National University. 1991. 
    16. Kim SM. Prevention and management of methicillin-resistant Staphylococcus aureus. Symposium of the Association of Hospital Infection Management. 1998;23-30. 
    17. Knox R, Smith JT. The nature of penicillin resistance in Staphylococci. Lancet. 1961;2:520-522. 
    18. Kundsin RB. Documentation of airborne infection during surgery. Ann N Y Acad Sci. 1980;353:255-261. 
    19. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial disk susceptibility test, 7th ed. Approved standards MA7. National Committee for Clinical Laboratory Standards. Wayne, PA, 2009. 
    20. Nobel WC, Virani Z, Cree RG. Co-transfer of vancomycin and other resistance genes from Enterococcus faecalis NCTC 12201 to Staphylococcus aureus. FEMS Microbiol Lett. 1992; 72:195-198 
    21. Park OH. Study on the isolation of bacteria from door knobs of hospital Kor J Med. 1973;25:637-640. 
    22. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233-2239. 
  • 이 논문을 인용한 문헌 (2)

    1. 2010. "" International journal of oral biology : official journal of the Korean Academy of Oral Biology and the UCLA Dental Research Institute, 35(4): 185~190     
    2. 2015. "" Journal of periodontal & implant science, 45(6): 223~228     

 저자의 다른 논문

  • 김신무 (23)

    1. 1999 "혈청이 마우스 간 세포주 BNL CL.2의 Nitric Oxide 생성에 미치는 영향" The Journal of biomedical laboratory sciences = 대한의생명과학회지 5 (1): 85~93    
    2. 2002 "대산의 분획별 추출물에서 항균활성 검색" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine 16 (6): 1184~1189    
    3. 2003 "Antibacterial Activity of Curcuma longa against Methicillin-resistant Staphylococcus aureus" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine 17 (2): 574~579    
    4. 2004 "Prevalence and Characterization of Vancomycin-Resistant Enterococci in Chicken Intestinles and Humans of Korea" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 27 (2): 246~253    
    5. 2004 "혈액에서 Sucrose 양성 Vibrio vulnificus 분리 1예" 대한임상검사학회지 = Korean journal of clinical laboratory science 36 (2): 69~75    
    6. 2005 "임상 검체에서 분리된 Bacillus cereus의 성상, 장독소 생성 및 항균제 감수성" 대한임상검사학회지 = Korean journal of clinical laboratory science 37 (1): 27~34    
    7. 2006 "Sucrose 발효 및 비발효 Vibrio vulnificus 균주의 생물학적 및 유전학적 성상 비교" Journal of bacteriology and virology : JBV 36 (4): 221~228    
    8. 2006 "치아 근관 감염 검체에서 검은 색소 형성 Prevotella species와 Porphyromonas species의 동정" 대한임상검사학회지 = Korean journal of clinical laboratory science 38 (1): 45~53    
    9. 2006 "만성 신부전증 환자에서 미토콘드리아 활성과 청력손실과의 연관성" 대한임상검사학회지 = Korean journal of clinical laboratory science 38 (3): 218~223    
    10. 2007 "환아의 혈액과 변에서 분리된 Shigella flexneri의 생화학적 성상, 항균제 감수성 및 Pulsed-Field Gel Electrophoresis 분석" 대한임상검사학회지 = Korean journal of clinical laboratory science 39 (3): 183~189    
  • 김강주 (33)

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 이용한 콘텐츠
이 논문과 함께 출판된 논문 + 더보기