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Journal of pharmacopuncture v.13 no.2, 2010년, pp.33 - 49   피인용횟수: 3

열처리 및 발효과정이 인삼 및 산양삼의 ginsenoside 함량에 미치는 영향
Component analysis of cultivated ginseng and mountain ginseng to the change of ginsenoside components in the process of heating and fermentation.

차배천    (상지대학교 보건과학대학 제약공학과   ); 윤휘철    (상지대학교 한의과대학 침구학교실   ); 이대호    (주식회사 지앤브이   ); 박재석    (상지대학교 한의과대학 침구학교실   ); 권기록    (상지대학교 한의과대학 침구학교실  );
  • 초록

    Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, mountain ginseng through component analysis, and to know the change of gin senoside components in the process of heating and fermentation Methods: Comparative analyses of ginsenoside $Rb_1$ , $Rb_2$ , Rc, Rd, Re, Rf, $Rg_1$ , $Rg_3$ , $Rh_1$ , and $Rh_2$ , from the cultivated ginseng 4 and 6 years, and mountain cultivated ginseng were conducted using HPLC (High Performance Liquid Chromatography, hereafter HPLC). And the same analyses were conducted in the process of heating and fermentation using mixed Lactobacillus rhamnosus, Lactobacillus plantarum, Bifidobacterium lactis for 7 days. Results: The change of ginsenosides to the process of red ginseng and fermentation, cultivated ginseng and mountain cultivated ginseng were showed another results. Mountain ginseng showed a lot of change compared with cultivated ginsengs. In the 7 days of fermentation, mountain ginseng showed that ginsenoside $Rg_1$ , $Rb_1$ , $Rb_2$ , Rc, and Rd were decreased and increased ginsenoside Re, Rf, $Rg_3$ and $Rh_1$ were increased compared with cultivated ginseng Conclusions: It seemed that ginsenosides of mountain cultivated ginseng was better resolved than cultivated ginseng because the difference of structure or distribution of ginsenosides in the condition of fermentation.


  • 주제어

    ginsenoside .   cultivated ginseng .   mountain ginseng .   red ginseng .   fermentation.  

  • 이미지/표/수식 (14)

    • HPLC condition for analysis of ginsenosides
    • Equation and R2 value of ginsenosides

    논문관련 이미지

  • 참고문헌 (23)

    1. Nam Ki Yeul. The comparative understanding between red ginseng and white ginsengs, processed ginsengs. j. ginseng res. 2005; 29(1): 1-18.     
    2. Matsuda H. Study on efficacy of processed ginseng, red ginseng. Natural Medicines. 1999; 53: 217-222. 
    3. Kitagawa L, Yoshikawa M, Yoshihara M, Hayashi T. and Taniyama, T. Chemical studies of crude drugs (1). Constituents of ginseng radix rubra. 1983; 103(6): 612-622. 
    4. Han BH, Pakr MH, and Han YN. Degradation of ginseng under mild acidic condition. Planta Med. 1982; 44: 146-149. 
    5. Suzuki Y, Ko SR, Choi KJ, Uchida K, Lee YG and Kim YH. Enzymatic glycosylation and hydrosis of ginseng saponins. Proc. 7th Symp. 1998; 373-374. 
    6. Hasegawa H, Sung JH, Matsumiya S and Uchiyama M. Main ginseng saponin metabolites formed intestinal Prevotella oris in hydrolyzing ginseng saponins. Planta Med. 1997; 63(5): 436-440. 
    7. Kong BM, Park MJ, Min JW, Kim HB, Kim SH, Kim SY and Yang DC. Physico-chemical characteristics of white fermented and red ginseng extracts. J. ginseng Res. 2008; 32(3): 238-243.     
    8. Wang W, Zhao Y, Rayburn ER, Hill DL, Wang H and Zhang R. In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng. Cancer Chemoth Pharmacol. 2007; 59: 589-601. 
    9. LY Wu J. Inhibitory effect of 20(S)-ginsenoside Rg3 on growth and metasis of Lewis pulmonary carcinoma. Zhonggliu Fangzhi Yanjiu. 2006; 33: 311-313. 
    10. David GP and David DK. Ginsenosides 20(S)-protopanaxadiol and Rh2 reduce cell proliferation and increase sub-G1 cells in two cultured intestinal cell lines, Int-407 and Caco-2. Can. J Physiol. Pharmacol. 2004; 82: 183-190. 
    11. Park SJ, Kim DH, Paek NS and Kim SS. Preparation and quality characteristics of the fermentation product of ginseng by lactic acid bacteria. J. Ginseng Res. 2006; 30(2): 88-94.     
    12. Brekhman. II. Panax ginseng, Gosudarst Isdat et Med, Lit. Leningard, 1957; 1-5. 
    13. Shibata, S., Tanaka, O., Soma, K., lita, Y., Ando, T. and Nakamura, H. Studies on saponins and sapogenins of ginseng. The structure of panaxatriol. Tetrahedron Lett., 1965; 3: 207-213. 
    14. Nam Ki Yeul. Contemporary Korean Ginseng. Korean Ginseng & Tobacco Research Institute. 1996; 1-54. 
    15. Park JD. Rescent studies on the chemical constituents of Korean Ginseng. Korean J. Ginseng Sci. 1996: 20(4): 389-415.     
    16. Jeong CS, Hyun JE and Kim YS. Anti-oxidative effect of ginsenoside Rb1 on the H치, ethanol-induced gastric tissue in rats. Kor. J Pharmacogn. 2002; 33(3): 252-256.     
    17. Choi KJ. The constituent of material ginseng and management of quality. Korean J Ginseng Sci. 1991; 15(3): 247-256.     
    18. Hideo H, Seong JH, Yasatosi M, Masamori W and Hur JD. Metabolites of ginseng saponin by enterobacteria and anti cancer substance include it's useful constituent. Korea Plant. 1998; No 10-164266-0000. 
    19. Choi SS, Lee JK, Han KJ, Lee HK, Lee J and Suh HW. Effects of ginsenoside Rd on nitric oxide system induced by lipopolysaccharide plus $TNF-<\alpha}$ in C6 rat glioma cells. Arch Pharm. Res. 2003; 26: 375-382.     
    20. Yokozawa T and Liu ZW. The role of ginsenoside Rd in cisplatin-induces acute renal failure. Ren. Fail. 2000; 22: 115-127. 
    21. Goldin BR. Health benefits of probitics. Br. J. Nutr. 1998; 80: 203-207. 
    22. Fuller R. Probiotics in man and animals. J. Applied Bacteriology. 1989; 66: 365-378. 
    23. Jeong HS, Lim CS, Cha BC, Choi SH, Kwon KR. Component analysis of cultivated ginseng, cultivated wild ginseng, and wild ginseng and the change of ginsenoside components in the process of red ginseng. J. of KPI. 2010; 13(1). 63-77.     
  • 이 논문을 인용한 문헌 (3)

    1. Kim, Min-Woo ; Song, Yun-Kyung ; Lim, Hyung-Ho 2011. "The Analysis of Study Trends of Wild ginseng, Bovis Calculus, Ursi Fel, Moschus and The Study on Applied Possibility as Obesity medications" 한방비만학회지 = Journal of Korean Medicine for Obesity Research, 11(2): 41~68     
    2. Shin, Eun Ji ; Cho, Chang-Won ; Kim, Young-Eon ; Han, Daeseok ; Hong, Hee-Do ; Rhee, Young Kyoung 2012. "Evaluation of Functional Properties of the Tissue Cultured Wild Ginseng Fermented by Lactobacillus sp." 韓國食生活文化學會誌 = Journal of the Korean Society of Food Culture, 27(6): 743~750     
    3. Seo, Hyobin ; Kim, Pan-Gi ; Ryu, Sungpil 2015. "The Study of Mountain Ginseng-added High Fat Diet on Anti-Apoptosis of Skeletal Muscle" 韓國林學會誌 = Journal of Korean Forest Society, 104(3): 383~389     

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