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Journal of ginseng research = 高麗人參學會誌 v.34 no.2, 2010년, pp.122 - 131   피인용횟수: 2
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Efficacy of Korean Red Ginseng Supplementation on Eradication Rate and Gastric Volatile Sulfur Compound Levels after Helicobacter pylori Eradication Therapy

Lee, So-Jung    (Department of Gastroenterology, Gachon Graduate School of Medicine Gil Medical Center   ); Park, Ji-Young    (Department of Gastroenterology, Gachon Graduate School of Medicine Gil Medical Center   ); Choi, Ki-Seok    (Laboratory of Translational Medicine, Gachon University Lee Gil Ya Cancer and Diabetes Institute   ); Ock, Chan-Young    (Laboratory of Translational Medicine, Gachon University Lee Gil Ya Cancer and Diabetes Institute   ); Hong, Kyung-Sook    (Laboratory of Translational Medicine, Gachon University Lee Gil Ya Cancer and Diabetes Institute   ); Kim, Yoon-Jae    (Department of Gastroenterology, Gachon Graduate School of Medicine Gil Medical Center   ); Chung, Jun-Won    (Department of Gastroenterology, Gachon Graduate School of Medicine Gil Medical Center   ); Hahm, Ki-Baik    (Department of Gastroenterology, Gachon Graduate School of Medicine Gil Medical Center  );
  • 초록

    This clinical study was performed to evaluate whether supplementation of proton pump inhibitor (PPI)-based triple therapy with Korean red ginseng can enhance Helicobacter pylori (H. pylori) eradication and reduce levels of halitosis-associated volatile sulfur compounds (VSCs) in the stomach. Seventy-six patients were randomized into an eradication regimen-only group (n=45) or an eradication regimen plus 10 weeks of Korean red ginseng supplementation group (n=31). The eradication regimen consisted of PPI b.i.d., clarithromycin 500 mg b.i.d., and amoxicillin 1 g b.i.d.. for seven days. Korean red ginseng supplementation commenced on the last day of the eradication regimen. $^{13}C$ -urea breath test and halimeter measurements were performed prior to protocol repetition. By intention-to-treat analysis, the H. pylori eradication rate in the Korean red ginseng group (77.4%, 24 of 31) was higher than that in the control group (45.0%, 26 of 45). However, by per protocol analysis, the eradication rate in the Korean red ginseng group was significantly higher than that in the control group (92.3%, 24/26 vs. 69.4%, 26/38; p


  • 주제어

    Helicobacter pylori .   Korean red ginseng .   Eradication .   Halimeter .   Supplementation .   Chronic atrophic gastritis.  

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  • 이 논문을 인용한 문헌 (2)

    1. 2010. "" Journal of ginseng research = 高麗人參學會誌, 34(2): 77~88     
    2. Kang, Seong Soo ; Kim, Myung Sook ; Kong, Myung Seok ; Kim, Yoo Hak ; Oh, Taek-Keun ; Lee, Chang Hoon 2014. "Effects of nitrogen fertigation on cucumber growth and nitrate in Soil under plastic film house" 농업과학연구 = CNU Journal of agricultural science, 41(4): 385~390     

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