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Food science and biotechnology v.19 no.3, 2010년, pp.777 - 784   SCIE 피인용횟수: 1
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Physicochemical Characteristics, Antimicrobial Activity, ACE Inhibitory Activity of Chitosan-salt, and Its Antihypertensive Effect

Kim, Hag-Lyeol    (Department of Food Engineering, Solar Salt & Halophyte R&D Center, Mokpo National University   ); Park, Soo-Mi    (Department of Food Engineering, Solar Salt & Halophyte R&D Center, Mokpo National University   ); Cho, Geon-Sik    (Biotech Co., Ltd.   ); Kim, Kye-Yeop    (Dongshin University   ); Kim, In-Cheol    (Department of Food Engineering, Solar Salt & Halophyte R&D Center, Mokpo National University  );
  • 초록

    This study was performed to investigate the physicochemical characteristics after producing chitosan-salt by adding chitosan to salt. $Cl^-$ value of chitosan-salt was same with that of the control group and that meant the salinity of the chitosan-salt was not different with that of the salt. While salt generally increases angiotensin converting enzyme (ACE) activity, chitosan-salt inhibited the ACE activity. For all microorganisms 3% chitosan-salt was the most effective in antimicrobial activity. When systolic blood pressure (SBP) of Sprague-dawley rats (SDR) was examined for 5 weeks to evaluate in vivo effects of chitosan-salt, all groups did not show significant difference between supplement period and group. In addition, plasma total cholesterol (TC) and triglyceride (TG) concentration were not different in all groups. This result was considered to be use of normotensive SDR so changes of SBP were investigated with spontaneous hypertensive rat (SHR). normal diet supplement group (NDSG) administered with captopril showed the largest decrease of SBP (p


  • 주제어

    chitosan-salt .   physicochemical characteristics .   antimicrobial activity .   angiotensin converting enzyme (ACE) inhibitory activity .   hypertension.  

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  • 이 논문을 인용한 문헌 (1)

    1. Kyung, Myungok ; Lim, Ji Ye ; Lee, Kyungsun ; Jung, Sangwon ; Choe, Keunbum ; Yang, Chang-Kun ; Kim, Yuri 2014. "Effects of short-term supplementation of erythritol-salt on urinary electrolyte excretion in rats" Journal of nutrition and health, 47(2): 99~105     

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