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Food science and biotechnology v.19 no.3, 2010년, pp.803 - 808   SCIE 피인용횟수: 1
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Physiological Activities of Ginsenoside-rich Fraction Isolated from Panax ginseng Leaves

Kim, Seong-Yeong    (Department of Food Science and Biotechnology, Kyonggi University   ); Kim, Sang-Hyek    (Department of Food Science and Biotechnology, Kyonggi University   ); Shin, Kwang-Soon    (Department of Food Science and Biotechnology, Kyonggi University   ); Lee, Ho    (Department of Food Science and Biotechnology, Kyonggi University  );
  • 초록

    In order to develop the new physiologically active materials from the leaves of Panax ginseng C.A. Meyer, the ginsenoside-rich fraction (GL-1) was isolated from ginseng leaves and physiological activities were examined. GL-1 contained crude saponin (ginsenosides, 58.00%) and component ginsenoside analysis using high performance liquid chromatography (HPLC) showed that the major ginsenosides of GL-1 were Re, Rg1, Rc, and F2 and their contents were 34.42, 20.73, 18.42, and 8.60%, respectively. ABTS and DPPH radical scavenging activities of GL-1 were 75.14 and 39.28% at $10,000\;{\mu}g/mL$ , respectively. Superoxide anion radical scavenging activity was 70.94% at $1,000\;{\mu}g/mL$ . GL-1 also expressed the considerable anti-complementary activity in dose-dependent manner. Results obtained by crossed immunoelectrophoresis using anti-human C3 and anti-complementary activity in the absence of $Ca^{++}$ ion suggested that complement activation by GL-1 from ginseng leaves occur via both alternative and classical pathways.


  • 주제어

    Panax ginseng .   ginseng leaf .   ginsenoside-rich fraction .   physiological activity .   anti-complementary activity.  

  • 참고문헌 (27)

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  • 이 논문을 인용한 문헌 (1)

    1. 2011. "" Journal of food science and nutrition, 16(4): 321~327     

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